A5088746993- Extracellular vesicles in disease
- Hydrogen's biological and therapeutic effects
- Polymer Nanocomposite Synthesis and Irradiation
- Viral Infections and Vectors
- RNA Interference and Gene Delivery
- Phytochemicals and Antioxidant Activities
- Genital Health and Disease
- Reproductive Biology and Fertility
- Autism Spectrum Disorder Research
- Colorectal Cancer Treatments and Studies
- Effects of Radiation Exposure
- Colorectal Cancer Screening and Detection
- Electrospun Nanofibers in Biomedical Applications
- Tissue Engineering and Regenerative Medicine
- Vitamin C and Antioxidants Research
- Hepatitis B Virus Studies
- Epigenetics and DNA Methylation
- Quantum Dots Synthesis And Properties
- Liver physiology and pathology
- Essential Oils and Antimicrobial Activity
- Liver Disease Diagnosis and Treatment
- Nuclear Receptors and Signaling
- Phytochemistry and Biological Activities
- MicroRNA in disease regulation
- Nanoparticles: synthesis and applications
Erciyes University
2019-2023
This study investigates in-vitro activities of phytochemicals in Callistemon citrinus against multi-resistant foodborne pathogens, alpha-glucosidase enzyme and MCF-7 cancer cell line. Assays were prepared with lyophilized extracts to determine antioxidant capacity, inhibition α-glucosidase growth bacteria. Annexin-V detection kit was used for apoptosis FT-IR spectroscopy confirm structural functional groups phytochemicals. Cytotoxicity the cells monitored xCELLigence Real-Time Cell Analyser....
Background and Objective: The study aims to evaluate the histopathological changes, enzymatic alterations, DNA damage in rat lungs induced by whole-body gamma irradiation as well evaluation of protective effect pycnogenol. Materials Methods: A hundred adult male rats were equally divided into ten groups including control, four antioxidants, γ-irradiation, antioxidant + γ-irradiations. This began day before radiation treatment continued for 3 days. pycnogenol was dissolved 5% dimethyl...
Objective: It is known that many genes are associated with colon cancer. We aimed to investigate the effect of gene mutations on metastasis and overall survival in metastatic non cancers. Methods: A total 50 patients (n=25) diagnosed cancer between 2010 2018 were included study. APC, MUTYH, RAD50, MEN1, ATM, PALB2, NSH2, BRCA1, BRCA2, MLH1, BRIP1, TP53, PTEN, BARD1, MSH6, PMS2, NBN, FAM175A evaluated using next generation sequencing method. The evaluated. Results: mean age without distant...
Aim: We aimed to evaluate the relationship between learning-memory difficulties and NEURL1 RGS14 genes in patients with autism spectrum disorders (ASD).Method: Forty children ASD (20 ASD, 20 high functioning (HFA)) healthy controls were enrolled this study. gene expressions blood samples of volunteers assessed by quantitative Real-Time PCR (qRT-PCR). The clinical demographical findings determined examined relation expressions.Results: According our findings, expression was decreased both...
Eksozomlar endozomdan köken almış, immün modülasyonda önemli role sahip, hücrelerarası etkileşimi sağlayan, nano boyutta biyomoleküllerdir. tetraspanninler, proteinler, Annexin ve Rab proteinleri gibi çok çeşitli zar proteinlerine sahiptirler bu içeriklere sahip olmaları ile enfeksiyon, sinir sistemi, kanser nörodejeneratif hastalıkların tedavi teşhisinde kullanılmaya adaydır. Hemen hemen bütün vücut sıvılarından salınan eksozomların hem homojen de sayıda izole edilebilmesi teşhis için...
Meme kanseri, en yaygın küresel malignitedir ve kansere bağlı ölümlerin ikinci önde gelen nedenidir. kanserinin erken teşhis edilmesi, farklı tedavi yöntemleri ile başarı oranını yükseltmektedir. Ancak ilerleyen evrelerde ise hem oranı düşmektedir de güncel yöntemlerinden kemoterapi veya radyoterapinin uygulanmasının hastaya yan etkileri olabilmektedir. Bu nedenle kişiye özel, etkinin olmadığı modellerini bulmak gerekir. Eksozomlar doğal nanopartiküller olup, aynı zamanda hücreler arası...
Aim: In this study, it was aimed to reveal a more effective model depending on the dose and time by evaluating histopathological properties biochemical parameters, such as alanine aminotransferase (ALT), aspartate (AST), albumin, triglyceride, cholesterol in carbon tetrachloride thioacetamide (CCl4 TAA) models. Method: Rats were divided into three groups for each intraperitoneally (i.p.) injected with CCl4 (0.5 ml/kg, 1.0 2.0 ml/kg) TAA (100 mg/kg, 200 mg/ kg, 300 mg/kg) 4, 6 8 weeks, times...
Abstract Introduction P-element induced wimpy testis-like 2 (Piwil2) is in the Piwi gene family. Piwil2 has important roles self-renewal mechanism of stem cell induction and progression numerous types human malignancies such as lung, breast, colon, prostate, cervical cancers. Glutathione S -transferase (GST) acts detoxification cancer metabolism. This study aimed to investigate effects protein on MCF10A MCF-7 at GST activity levels. Materials/Methods MCF-7/Piwil2 MCF10A/Piwil2, transfected...