David Gárate

ORCID: 0000-0003-3622-755X
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About
Contact & Profiles
Research Areas
  • Acne and Rosacea Treatments and Effects
  • Dermatology and Skin Diseases
  • Hair Growth and Disorders
  • Dermatologic Treatments and Research
  • melanin and skin pigmentation
  • Oral Health Pathology and Treatment
  • Chemotherapy-related skin toxicity
  • Immunotherapy and Immune Responses
  • Skin Protection and Aging
  • Autoimmune and Inflammatory Disorders
  • Retinoids in leukemia and cellular processes
  • Immune Response and Inflammation
  • Dialysis and Renal Disease Management
  • Autoimmune Bullous Skin Diseases
  • Skin Diseases and Diabetes
  • T-cell and B-cell Immunology
  • Burn Injury Management and Outcomes
  • Psoriasis: Treatment and Pathogenesis
  • Drug-Induced Adverse Reactions
  • Allergic Rhinitis and Sensitization
  • Cancer Immunotherapy and Biomarkers
  • IL-33, ST2, and ILC Pathways
  • Wound Healing and Treatments
  • Health Literacy and Information Accessibility
  • Cerebral Venous Sinus Thrombosis

John Sealy Hospital
2023-2025

The University of Texas Medical Branch at Galveston
2023-2025

Baylor College of Medicine
2023

University of Chile
2010-2013

Instituto de Neurociencia Biomédica
2013

Millennium Institute on Immunology and Immunotherapy
2013

Student mental health concerns can manifest in several forms. Medical students juggling a multitude of trials (i.e., intense academic rigor, financial debt, sleep deprivation, lack control, continual exposure to sickness and death, training mistreatment) help explain the higher prevalence psychological disorders within this population. Furthermore, these difficulties are not static; certain challenges move into forefront as face key transition points schooling. Primary examples include entry...

10.1080/08998280.2023.2187207 article EN Baylor University Medical Center Proceedings 2023-03-16

Abstract Background Generation of tolerogenic dendritic cells (TolDCs) for therapy is challenging due to its implications the design protocols suitable clinical applications, which means not only using safe products, but also working at defining specific biomarkers TolDCs identification, developing shorter DCs differentiation methods and obtaining with a stable phenotype. We describe here, short-term protocol generation, are characterized in terms phenotypic markers, cytokines secretion...

10.1186/1479-5876-11-128 article EN cc-by Journal of Translational Medicine 2013-05-24

Abstract Objective Dendritic cells (DCs) modulated with lipopolysaccharide (LPS) are able to reduce inflammation when therapeutically administered into mice collagen‐induced arthritis (CIA). The aim of this study was uncover the mechanisms that define tolerogenic effect short‐term LPS‐modulated DCs on CIA. Methods Bone marrow–derived were stimulated for 4 hours LPS and characterized their expression maturation markers cytokine secretion profiles. Stimulated treated SB203580 or SB431542...

10.1002/art.37702 article EN Arthritis & Rheumatism 2012-09-13

Data sharing is not applicable to this article as no new data were created or analyzed in study. Table S1. S2. Please note: The publisher responsible for the content functionality of any supporting information supplied by authors. Any queries (other than missing content) should be directed corresponding author article.

10.1111/all.16199 article EN Allergy 2024-06-16

Background. Pharmacologically modulated dendritic cells (DCs) have been shown to restore tolerance in type II collagen-(CII-) induced arthritis (CIA). We examined the effect of dexamethasone (DXM) administration as a preconditioning agent, followed by an injection lipopolysaccharide-(LPS-) stimulated and CII-loaded DCs on CIA course. Methods. After induction, mice pretreated with DXM were injected 4-hour LPS-stimulated loaded CII (DXM/4hLPS/CII/DCs). Results. Mice DXM/4hLPS/CII/DCs displayed...

10.1155/2013/296031 article EN cc-by Clinical and Developmental Immunology 2013-01-01

This cohort study investigates whether calcitonin gene-related peptide inhibition is associated with reduced rates of developing acne or rosacea in patients who experience migraines.

10.1001/jamadermatol.2024.2182 article EN JAMA Dermatology 2024-08-01
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