- Reconstructive Surgery and Microvascular Techniques
- Head and Neck Cancer Studies
- Reconstructive Facial Surgery Techniques
- Tracheal and airway disorders
- Head and Neck Surgical Oncology
- Dysphagia Assessment and Management
- Surgical site infection prevention
- Esophageal and GI Pathology
- Trauma Management and Diagnosis
- Cleft Lip and Palate Research
- Sarcoma Diagnosis and Treatment
- Nerve Injury and Rehabilitation
- Bone fractures and treatments
- Cancer Diagnosis and Treatment
- Facial Trauma and Fracture Management
- Esophageal Cancer Research and Treatment
- Salivary Gland Tumors Diagnosis and Treatment
- Bone Tumor Diagnosis and Treatments
- Oral and Maxillofacial Pathology
- Voice and Speech Disorders
- Vascular Procedures and Complications
- Lung Cancer Diagnosis and Treatment
- Orthopedic Surgery and Rehabilitation
- Tumors and Oncological Cases
- Oral health in cancer treatment
Hokkaido University of Science
2025
Hokkaido Pharmaceutical University
2024
Iwate Medical University
2017-2024
National Cancer Center Hospital East
2011-2023
Jikei University School of Medicine
2017
Kyushu University
2017
National Cancer Center
2001-2016
Creative Commons
2014
Tokyo National Hospital
2013-2014
Sapporo City General Hospital
2013
The authors examined donor-site complications and morbidity in 37 patients after reconstruction with free or pedicled anterolateral thigh flaps. Intraoperative assessment included damage to the vastus lateralis muscle whether main pedicle of rectus femoris had been killed. Postoperative donor site wound healing, range motion, strength, gait, sensation. Patients were surveyed a questionnaire about fatigue their activities daily life appearance site. All 32 who underwent primary skin closure...
The authors examined donor-site complications and morbidity in 37 patients after reconstruction with free or pedicled anterolateral thigh flaps. Intraoperative assessment included damage to the vastus lateralis muscle whether main pedicle of rectus femoris had been killed. Postoperative donor site wound healing, range motion, strength, gait, sensation. Patients were surveyed a questionnaire about fatigue their activities daily life appearance site. All 32 who underwent primary skin closure...
Abstract Objectives/Hypothesis For reconstruction after subtotal or total glossectomy, both preserving the larynx and maintaining postoperative swallowing speech functions can greatly improve quality of life; however, functional results are often unstable. Our experiences suggest that insufficient flap volume in oral area prolapse preserved affect function. The objective was to investigate relations shape reconstructed tongue functions. Study Design classified on basis magnetic resonance...
Activated cancer-associated fibroblasts (CAFs) and that have undergone the epithelial-mesenchymal transition (EMT) in cancer stroma contribute to tumor progression metastasis. However, no reports investigated CAF phenotype its clinicopathological relevance cutaneous malignant tumors, including basal cell carcinoma (BCC), squamous (SCC), melanoma (MM). Here, we tumors based on their histology immunohistochemical expression of CAF-related markers, adipocyte enhancer-binding protein 1 (AEBP1),...
The free or pedicled anterolateral thigh flap was introduced for the reconstruction of large abdominal wall defects. This is superior to tensor fasciae latae musculocutaneous in several respects. These include wide, reliable skin territory (which can reach level knee) and long pedicle. Therefore, a with blood circulation easily be positioned above umbilicus. In addition, has greater freedom orientation used repair larger defects than flap. Seven patients whom had been reconstructed flaps...
The free or pedicled anterolateral thigh flap was introduced for the reconstruction of large abdominal wall defects. This is superior to tensor fasciae latae musculocutaneous in several respects. These include wide, reliable skin territory (which can reach level knee) and long pedicle. Therefore, a with blood circulation easily be positioned above umbilicus. In addition, has greater freedom orientation used repair larger defects than flap. Seven patients whom had been reconstructed flaps...
Abstract Objectives The aim of the present study was to clarify clinicopathological characteristics, reconstruction methods after resection, and prognosis cervical esophageal squamous cell carcinoma. Methods Seventy‐four with carcinomas esophagus not previously treated who underwent esophagectomy or total without laryngectomy were retrospectively analyzed. Results operative morbidity in‐hospital mortality rates 34% (25 patients) 4% (3 patients), respectively. Alimentary continuity achieved...
The transcription factor brain and muscle Arnt-like protein-1 (BMAL1) is a clock protein involved in various diseases, including atherosclerosis cancer. However, BMAL1's involvement kidney fibrosis the underlying mechanisms remain largely unknown, gap addressed this study. Analysis through Masson's trichrome Sirius red staining revealed that all groups exposed to unilateral ureteral obstruction showed increased BMAL1 expression accompanied by TGF-β1 elevated key markers, α-SMA, compared with...
The aim of this study was to evaluate our personal experience with video-assisted thoracoscopic lobectomy and compare survival between procedure conventional via open thoracotomy in patients clinical stage IA non-small cell lung carcinoma. Between May 1997 December 2004, 140 carcinoma had either VATS (VATS group, 84 patients) or standard (open 56 performed hospital. We compared overall survival, disease-free recurrence the two groups. rate five years after surgery 72% group 82% group. There...
Introduction. Although several intercalary reconstructions after resection of a lower extremity malignant bone tumor are reported, there no optimal methods which can provide long-term reconstruction with fewest complications. We present the outcome using devitalized autograft and vascularized fibula graft composite. Materials Methods. conducted retrospective review 11 patients (7 males, 4 females; median age 27 years) undergoing (pasteurization (n = 6), deep freezing 5)) composite for tumors...
In patients undergoing limb-salvage internal hemipelvectomy, pelvic ring reconstruction is mandatory to maintain the stability of pelvis and spinal column, which finally expected achieve a good functional outcome. However, no optimal method has been established. addition, previous reports have highlighted long-term complications after hemipelvectomy. We aimed analyze outcome using double-barreled free vascularized fibula graft (VFG) hemipelvectomy with special reference complications.We...
The frequency of postoperative complications is used as an indicator surgical quality; however, comparison outcomes hampered by a lack agreement on the definition and their severity. A standard grading system for necessary to improve quality clinical research reporting in head neck reconstruction.The aim this study was compare morbidity after microvascular reconstruction between patients with versus without history prior radiation therapy (RT) using Clavien-Dindo classification. group 274...
Background: Although hemipelvectomy has been the standard treatment for malignant tumors of pelvis, limb salvage surgery is now choice, even patients with advanced tumors. For these patients, pelvic reconstruction needed to maintain stability pelvis and spinal column allow ambulation. In this report, authors' experiences ring are described. Methods: Pelvic free double-barreled vascularized fibular grafts was performed after resection in five patients. The graft fixed a fixation plate screws...
Prolonged bed rest and elevation have traditionally been considered necessary after free-flap transfer to the lower extremities. In this retrospective study, we tried mobilize patients early extremity by means of flow-through anastomosis for both arteries veins.This study included 13 consecutive who underwent immediate wide resection soft-tissue tumors from March 2012 through July 2013. The defects were above knee in 5 below 8 patients. all patients, was used veins. mobilized starting on...
Abstract Objectives/Hypothesis Defects of the lateral and superior oropharyngeal wall are difficult to reconstruct because their complicated anatomy possibility causing velopharyngeal incompetence. The objective was investigate problems reconstruction postoperative function. Study Design were classified into three types (I, II, III) according extent. Four operative procedures performed: Patch, Jump, Denude, Gehanno methods, which include a lateral–posterior pharyngeal advancement flap....
To obtain better functional results after reconstruction to treat facial palsy in the patients with preoperative and intraoperative factors that might inhibit recovery, authors have used free vascularized nerve grafts immediately reconstruct severed nerves.The indications for were 1) scarred recipient bed attributable previous operations, 2) a history of irradiation at wound, 3) skin defects over graft tumor ablation, 4) patient age greater than 60 years, 5) palsy.Four types nerves used....
To examine the efficacy and safety of free jejunal transfer after larynx-preserving esophagectomy in patients with cervical esophageal carcinoma, especially a high tumor involving hypopharynx.A retrospective analysis carcinoma who underwent esophagectomy.The subjects were 32 microvascular transfer. Fifteen had that involved hypopharynx (high-tumor group), 17 low did not involve (low-tumor group). For each group, mortality, morbidity (anastomotic leakage, wound infection, stricture, recurrent...
Background: Transfer of a vascularized fibular graft is the method first choice for reconstruction defects long bones. In particular, fibula head preferred patients with bone upper limb involving distal radius or proximal humerus. The aim present study was to analyze operative results, complications, and postoperative function after transfer indications this procedure. Methods: From 1998 through 2008, performed in eight reconstruct following resection tumors limb. primary site tumor humerus...