Recently, medical rapid prototyping (MRP) models, fabricated with computer-aided design and manufacture (CAD/CAM) techniques, have been applied to reconstructive surgery in the treatment of head neck cancers. Here, we tested use preoperatively manufactured reconstruction plates, which were produced using MRP models. The clinical efficacy esthetic outcome these products mandibular was evaluated. A series 28 patients malignant oral tumors underwent unilateral segmental resection mandible...

The free or pedicled anterolateral thigh flap was introduced for the reconstruction of large abdominal wall defects. This is superior to tensor fasciae latae musculocutaneous in several respects. These include wide, reliable skin territory (which can reach level knee) and long pedicle. Therefore, a with blood circulation easily be positioned above umbilicus. In addition, has greater freedom orientation used repair larger defects than flap. Seven patients whom had been reconstructed flaps...

The free or pedicled anterolateral thigh flap was introduced for the reconstruction of large abdominal wall defects. This is superior to tensor fasciae latae musculocutaneous in several respects. These include wide, reliable skin territory (which can reach level knee) and long pedicle. Therefore, a with blood circulation easily be positioned above umbilicus. In addition, has greater freedom orientation used repair larger defects than flap. Seven patients whom had been reconstructed flaps...

Latissimus dorsi flaps are typically vascularized by the thoracodorsal or intercostal artery perforators, while cases describing use of lumbar perforators exceedingly rare. This report presents a case 74-year-old woman presenting with refractory ulcer associated an exposed spinal fixation device. Reconstruction was successfully performed using pedicled latissimus flap perforators. Preoperative indocyanine green (ICG) fluorescence angiography confirmed adequate perfusion from Postoperative...

Two factors contribute to the stability of thumb: static provided by bones, joints, and ligaments, dynamic muscles. Proximal types polydactyly, such as Wassel Ⅴ Ⅵ, are often associated with thenar dysplasia, which is thought lack sufficient stability. Therefore, in cases proximal polydactyly where instability at metacarpophalangeal (MCP) joint severe, becomes important. No reports have been published on ligament reconstruction during primary collateral for thumb a pediatric congenital...

Competitive inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase (the statins) that inhibit the synthesis mevalonic acid are in wide use for treatment hypercholesterolemia. Although antitumor effects on a variety cell types have been reported statins, effect simvastatin (one human melanoma lines is not known. Here, we report lines. We treated lines, A375M, G361, C8161, GAK, and MMAc with various concentrations 1 to 3 days. To investigate simvastatin, analyzed viability, morphologic...

Microsurgical lymphaticovenous implantation in lymphedema is done to create a shunt by an of collecting lymphatics into the small vein, as reported previously. The authors have recently introduced ultrasonograpy and indocyanine green fluorescence lymphography this procedure.Nine cases postmastectomy had received preoperative venous marking using ultrasonography lymphatic mapping lymphography. concept modification pick up most effective point for microsurgical that involves both subcutaneous...

The dry weight of tendon tissue is accounted for mainly by collagen fibers. Accordingly, the tendon-healing process primarily involves repair During remodeling phase healing, newly proliferating fibers are transformed into a mature repaired tendon. Despite importance this phenomenon, details fibrous rebuilding have not been reported previously. aim study was to visualize ultrastructural changes and obtain clear understanding reorganization in site, using rat Achilles tendons. We used...

To create a moist environment for wound healing, hydrocolloid-sheet composed of alginate, chitin/chitosan and fucoidan (ACF-HS) has been developed as functional dressing. ACF-HS gradually adsorbed medium without any maceration the mediu

Objective: Patients with critical limb ischaemia (CLI) lack sufficient blood flow in to the limb, which leads difficulties normal wound healing process. Therefore, maggot debridement therapy (MDT) has not generally been recommended for CLI patients. We evaluated effectiveness of bed preparation by MDT patients who had undergone mid-foot amputation. Methods: underwent amputation after angioplasty between April 2014 and October 2016 were retrospectively investigated classifying them into an...

Abstract We present a follow‐up study of 18 patients with upper limb lymphedema treated by microsurgical lymphaticovenous implantation (MLVI) combined compression therapy. This technique provides increased lymphatic flow through newly created bypasses the MLVI surgery, assistance for pumping function in lymphatics Preoperative assessment affected was performed average enlargement edema circumference (AEEC), comparing and normal circumferences. Objective improvement analyzed percent reduction...

Abstract An alternative approach, using a combination of nerve crossover and cross‐nerve grafting technique in single‐stage procedure, was developed for the reconstruction reversible facial palsy. This combined provides some benefits such as early reanimation resulting from less morbidity sufficient innervation with an application end‐to‐side anastomosis method, efficient neural regeneration due to coaptation intratemporal nerve. Facial rehabilitation, based on double by hypoglossal...

Phacomatosis pigmentovascularis is a rare congenital condition characterized by vascular malformation associated with extensive pigmented nevi. Even though it forms large, prominent skin lesion, therapy for phacomatosis rarely discussed. To the best of our knowledge, this first report type II treated combined laser using Q-switched alexandrite and long-pulsed dye lasers.In two cases reported here, 2-week-old Japanese baby girl was given diagnosis Klippel-Trénaunay syndrome because port-wine...

Abstract Background Oral modiolus reconstruction is important in unilateral oral commissure removal including the modiolus. However, proper procedure not yet established. We performed free‐flap for full‐thickness defects involving combined with using a fascial sling. Patients and methods From 2008 to 2018, six carcinoma patients, aged 65 86 years, underwent after tumor resection. The resulting lip of 10% 80% were labial (two patients), buccal mixed patients). Results Five anterolateral thigh...

Scars are composed of stiff collagen fibers, which contract strongly owing to the action myofibroblasts. To explore substances that modulate scar contracture, fibroblast-populated lattice (FPCL) model has been used. However, molecular signature patient-derived FPCL not verified. Here, we examined whether keloid reflects contraction, analyzing detailed gene expression changes using comprehensive RNA sequencing and histological morphology, revealed these models consistent with during human...

We evaluated the effects of presurgical nasoalveolar molding (NAM) with an orthopedic appliance and compared them a passive method (Hotz plate, HP), focusing on naris morphology width alveolar palate cleft gap. The subjects were 28 unilateral complete lip patients treated primary cheiloplasty at Tsukuba University Hospital from 2004 to 2011. Thirteen preoperatively NAM (NAM group), 15 HP (HP group). surgical outcome was assessed according left-right symmetry, as measured by area ratio,...

Background: The purpose of this study was to clarify the appropriate use unfractionated heparin as an anticoagulation agent after digital replantation. Methods: This a prospective, randomized, single-blind, blinded-endpoint method, three-arm, parallel-group, controlled clinical trial conducted at single institution. A total 88 patients (101 fingers) following amputation and subsequent repair by anastomosis both arteries veins were randomly allocated into three groups: (1) control group (no...