A5102847923- Reservoir Engineering and Simulation Methods
- Neuroscience and Neural Engineering
- Drilling and Well Engineering
- Advanced Sensor and Energy Harvesting Materials
- Hydraulic Fracturing and Reservoir Analysis
- Risk and Safety Analysis
- Occupational Health and Safety Research
- Metal and Thin Film Mechanics
- CO2 Sequestration and Geologic Interactions
- Seismic Imaging and Inversion Techniques
- Enhanced Oil Recovery Techniques
- Tribology and Wear Analysis
- High-Temperature Coating Behaviors
- Oil and Gas Production Techniques
- RNA and protein synthesis mechanisms
- Hydrocarbon exploration and reservoir analysis
- Immune cells in cancer
- Advanced biosensing and bioanalysis techniques
- RNA modifications and cancer
- Immune Cell Function and Interaction
- RNA Interference and Gene Delivery
- Inflammasome and immune disorders
- Silicon Nanostructures and Photoluminescence
- Genomics and Chromatin Dynamics
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
University of Chicago
2019-2024
Seoul National University
2024
Pusan National University
2009-2023
Pusan National University Hospital
2023
Yonsei University
2023
University of Ulsan
2023
Asan Medical Center
2023
Ulsan College
2023
Ewha Womans University
2019-2022
Stony Brook University
2022
Melanoma is one of the most deadly and therapy-resistant cancers. Here we show that N
Abstract Transient electronics represents an emerging technology whose defining feature is ability to dissolve, disintegrate or otherwise physically disappear in a controlled manner. Envisioned applications include resorbable/degradable biomedical implants, hardware-secure memory devices, and zero-impact environmental sensors. 2D materials may have essential roles these systems due their unique mechanical, thermal, electrical, optical properties. Here, we study the bioabsorption of CVD-grown...
Single-crystalline silicon nanomembranes (Si NMs) represent a critically important class of material for high-performance forms electronics that are capable complete, controlled dissolution when immersed in water and/or biofluids, sometimes referred to as type "transient" electronics. The results reported here include the kinetics hydrolysis Si NMs biofluids and various aqueous solutions through range relevant pH values, ionic concentrations temperatures, dependence on dopant types...
Semiconducting materials are central to the development of high-performance electronics that capable dissolving completely when immersed in aqueous solutions, groundwater, or biofluids, for applications temporary biomedical implants, environmentally degradable sensors, and other systems. The results reported here include comprehensive studies dissolution by hydrolysis polycrystalline silicon, amorphous silicon-germanium, germanium solutions various pH values temperatures. In vitro cellular...
On-demand, localized release of drugs in precisely controlled, patient-specific time sequences represents an ideal scenario for pharmacological treatment various forms hormone imbalances, malignant cancers, osteoporosis, diabetic conditions and others. We present a wirelessly operated, implantable drug delivery system that offers such capabilities form undergoes complete bioresorption after engineered functional period, thereby obviating the need surgical extraction. The device architecture...
Global genome repair (GGR), a subpathway of nucleotide excision repair, corrects bulky helix-distorting DNA lesions across the whole and is essential for preventing mutagenesis skin cancer. Here, we show that METTL14 (methyltransferase-like 14), critical component N6-methyladenosine (m6A) RNA methyltransferase complex, promotes GGR through regulating m6A mRNA methylation-mediated DDB2 translation suppresses ultraviolet B (UVB) radiation-induced tumorigenesis. UVB irradiation down-regulates...
The cortical actin cytoskeleton plays a critical role in maintaining intestinal epithelial integrity, and the loss of this architecture leads to chronic inflammation, as seen inflammatory bowel disease (IBD). However, exact mechanisms underlying aberrant remodeling pathological states remain largely unknown. Here, we show that subset patients with IBD exhibits substantially higher levels tripartite motif-containing protein 40 (TRIM40), gene is hardly detectable healthy individuals. TRIM40 an...
Recent development of flexible/stretchable integrated electronic sensors and stimulation systems has the potential to establish an important paradigm for implantable devices, where shapes mechanical properties are matched those biological tissues organs. Demonstrations tissue immune biocompatibility fundamental requirements application such kinds electronics long‐term use in body. Here, a comprehensive set experiments studies on four representative device platforms, selected basis their...
Abstract CD160 and BTLA both bind to herpes virus entry mediator. Although a negative regulatory function of in natural killer T (NKT) cell activation has been reported, whether is also involved unclear. By analyzing −/− mice mixed bone marrow chimeras, we show that not essential for NKT development. However, exhibit severe liver injury after vivo challenge with α-galactosylceramide (α-GalCer). Moreover, are more susceptible Concanavalin A challenge, display elevated serum AST ALT levels,...
Video head impulse tests (vHITs), assessing the vestibulo-ocular reflex (VOR), may be helpful in differential diagnosis of acute dizziness. We aimed to investigate vHITs patients with posterior circulation stroke (PCS) examine whether these findings could exhibit significant abnormalities based on lesion locations, and evaluate diagnostic value vHIT differentiating dizziness between PCS vestibular neuritis (VN).We prospectively recruited consecutive 80 analyzed according presence dorsal...
The present study is aimed at the development of compositional simulation models co-injection CO2 and CH4 during water-alternating-gas (WAG) process in order to assess efficiency carbon capture storage combination with enhanced oil recovery (CCS-EOR). occupies more reservoir pore volume causes higher pressure than WAG, thus leading an early EOR performance. However, overall performance method becomes lower that WAG due reduced miscibility sweep upon further addition. decrease gas...
Tributyltin (TBT), an endocrine disrupting chemical, has been reported to decrease ovarian function by causing apoptosis in the ovary, but mechanism is not fully understood. Therefore, we examined whether TBT increases expression of adipogenesis-related genes ovary and increased these associated with induction.Three-week-old Sprague-Dawley rats were orally administered (1 or 10 mg/kg body weight) sesame oil as a control for 7 days. The ovaries obtained weighed on day 8, then they fixed...