Insights into antibiotic-carrier interactions in the silk-fibroin-based nanoparticles and considerations on formulation process greenness are limited. Hence, this work developed characterized polyethylene glycol-functionalized silk fibroin for oral delivery of cefotaxime (PEG/SFPs-CTX), with a focus silico simulations greenness. The particles were formulated by two methods co-condensation adsorption. Dependent processes, possessed spherical shape, smooth/rough surfaces, nanosize (170-650...

In this paper, a semi-active suspension Model Predictive Control (MPC) is designed for full vehicle system equipped with 4 dampers. The main challenge in the control problem to tackle dissipativity constraints of are here recasted as input and state constraints. controller MPC framework where effects unknown road disturbances taken into account. An observer approach allows estimate disturbance information be used by during prediction step. Then, law estimation (but without preview) computed...

Fibroin nanoparticles (FNP) have been employed in numerous biomedical applications. However, limited research has focused on the oral delivery of FNP and in-depth molecular interactions between encapsulated drug FNP. Therefore, this work developed FNP, functionalized with poly(vinyl alcohol) (PVA), to orally deliver zwitterionic ciprofloxacin, interactions. The particles were formulated using both desolvation (the precipitated during formulation) adsorption adsorbed surfaces) methods....

One important test for the formation and grading of a lithium-ion battery is to confirm performance while discharging it down zero volts. In this paper, novel soft-switching charge/discharge converter with voltage discharge function proposed. The proposed able until its reaches phase-shift full-bridge method used charge current-fed push-pull bidirectional switches discharge. Zero switching (ZVS) achieved at turn-on during operation. ZVS current turn-off are controllers designed taking into...

The main antioxidant polyphenol compounds in the mango ( Mangifera indica L.) leaf extract are susceptible to environmental degradations. Thus, biomedical applications, is commonly encapsulated a carrier. However, most studies employed synthetic carrier materials that could affect human health, and complicated formulation procedure hinder scalability. Therefore, this work, for first time, explored use of silk fibroin (an FDA-approved biomaterial), nanoparticles platform, encapsulate deliver...

This paper addresses a semi-active suspension control of the full vehicle equipped with 4 controlled dampers by using 7 degree freedom (DOF) vertical model. First, dissipativity conditions are recast as saturation on inputs. Then, controller is derived solving state feedback design problem for class linear parameter-varying (LPV) system in presence actuator saturation. To this aim, generalized sector condition LPV applied to treat nonlinearity, caused input and relax stability condition. The...

Numerous parameters (environmental conditions, material and equipments design) affect the ageing (and consequently lifetime) of Electrical Insulation System (EIS) motors supplied by static converters. In order to find a modeling lifetime such materials, accelerated tests have be considered. The problem is that if we consider all relevant parameters, these become costly take lot time. Consequently topic this study use statistical method called: `Design Experiments' (DoE) obtain only...

In this paper, a novel fault tolerant control is proposed to accommodate damper faults (oil leakages) in semi-active suspension system based on quarter-car vehicle model. The accommodation the Linear Parameter Varying (LPV) strategy and involves two steps. At first, fast time-varying estimated by using adaptive estimation (FAFE) algorithm, an unknown input observer. Thanks information about fault, dissipativity domain of adapted according fault. Then single LPV controller developed manage...

In this paper, an actuator fault estimation problem is tackled, based on the LPV approach. First, modeled in form of a multiplicative by using constant coefficient representing loss efficiency actuator's power α. Therefore, time varying faulty can be transformed into Then, system rewritten switched system. The α and states are estimated extended observer. stability performance observer ensured considering time-dependent Lyapunov function. gains derived LMI solutions for polytopic systems....

The dielectric and mechanical properties of standard (PEI), nanoscale-filled microscale-filled varnishes are detailed analyzed in this communication. Fumed silica (10 nm 400 nm) have been tested as a filler. A particular attention has paid to partial discharge inception voltage, lifetime under pulse voltage bonding strength which crucial for varnish be used rotating machines fed by inverters.

The resistance to partial discharges of pure, microfilled and nanofilled Polyetherimide varnish for low voltage motors fed by inverters is presented. Micro nano-sized Silica particles (1.5 % wt) are used as fillers. Experimental results lifetime versus temperature (-55 180°C), frequency (5 15 kHz) level the applied square (+/- 1 kV +/- 3 kV) clearly demonstrate that nanofillers more efficient than microfillers. polyetherimide found be up thirty times higher standard one. Crucial properties a...

The semi-active suspension control problem faces the challenge of dissipativity constraints dampers. This induces some compromises (actuator saturation, comfort, road holding...) which need to be taken into account in design step. In this paper, a state feedback input constrained for LPV systems is considered with H <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">∞</sub> performance objective. Stabilization conditions based on Finsler's Lemma...

Abstract Predicting the electric field distribution under dc stress within polymeric insulations remains a challenge, as space charge behaviour is still difficult to understand in these materials. Charge generation often thought arise from injection at electrodes. Hence, surface roughness should be taken into account, it strengthens locally and therefore promotes some points. A transport model has been developed 2D account for roughness. The first validated with help of previous results,...

In this paper, the actuator fault estimation problem of semi-active suspension systems is considered. For instance, an oil leakage in a damper could cause reduction damping force. The requires modeling (both multiplicative and additive models can be used). Three observer-based approaches are compared for estimation: observer using fast adaptive (FAFE) approach (used faults), parametric (AO) switched LPV (LPVO) intended to estimate mulplicative faults). Since strongly affected by unknown road...

Đặt vấn đề: Amlodipin besilat là thuốc thuộc nhóm chẹn kênh canxi, indapamid một sulfonamid lợi tiểu, sự kết hợp giữa hai này trong cùng dạng bào chế mang lại nhiều ưu điểm như dễ tuân thủ điều trị, cho sinh khả dụng cao, hạn tác không mong muốn của từng loại giúp kiểm soát được huyết áp và làm giảm biến cố tim mạch. Do đó, việc nghiên cứu định lượng đồng thời amlodipin cần thực hiện để cơ sở đánh giá hàm hoạt chất sản phẩm chế. Mục tiêu cứu: Khảo sát kiện sắc ký, xây dựng thẩm phương pháp...

A large amount of parameters related to both operating conditions and material design affects the electrical ageing low voltage rotating machine insulation. Accelerated tests are usually undertaken in order develop a theory describe process determine lifetime model these materials. However, best our knowledge, there is no complete allowing prediction an insulation from accelerated tests, since many possible failure mechanisms various synergetic effects between them. Another problem with that...

In this paper, we present a motion-scheduled LPV/H <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">∞</sub> suspension controller that takes into account the three main motions of vehicle vertical dynamics: bounce, roll and pitch motions. The new approach aims, by using motion detection method, at designing which is able to adapt forces four corners vehicle, in order mitigate road-induced effects. strategy based on supervison load transfer...

Abstract Background Infectious diseases, especially those caused by multidrug-resistant bacteria, are becoming a serious problem worldwide because of the lack effective therapeutic agents. Moreover, most antifungal drugs exhibit low efficacy and high toxicity similarity between fungal human cells. These issues warrant search for potential new Objectives To synthesize potent 2-(2-iodophenylimino)-5-arylidenethiazolidin-4-one derivatives, improve synthetic process, elucidate their structures,...

Results of DC conduction, breakdown strength and electroluminescence standard (PEI), nanoscale-fllled microscale-fllled varnishes are described analyzed in this communication. Silica (10nm 400nm) has been used as a filler to increase the lifetime such submitted partial discharge activity (varnish be rotating machines fed by inverters). Experimental results have shown that dielectric properties nanofilled varnish, which exhibits higher PD under stress, not highly affected fillers. On...

This study investigated the potential of endophytic bacteria isolated from native cassava (Manihot esculenta KM98-7) to enhance plant growth and yield under greenhouse field conditions. Eleven bacterial strains (TL1 TL11) were assessed for nitrogen fixation, phosphate solubilization, indole acetic acid (IAA) synthesis. TL4 TL8 exhibited superior capabilities, with producing highest levels NH4+ (14.95 mg l-1) IAA (46.57 l-1). Molecular identification revealed that closely related Burkholderia...

A recent technique, using to potentially replace the conventional impregnating one in low voltage electric motors, has been studied this communication. The technique that uses both primary and secondary insulations; i.e.: enamel varnish, compared which only component, self-bonding wires. Self-bonding wires polymerization is very quick of technique. Environmental impact dielectric mechanical properties these two techniques have estimated compared. goal estimate if not a better environmental...