Fatimah Al-Otibi

ORCID: 0000-0003-3629-5755
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About
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Research Areas
  • Plant Pathogens and Fungal Diseases
  • Mycorrhizal Fungi and Plant Interactions
  • Nanoparticles: synthesis and applications
  • Essential Oils and Antimicrobial Activity
  • Fungal Biology and Applications
  • Plant-Microbe Interactions and Immunity
  • Medicinal Plants and Neuroprotection
  • Yeasts and Rust Fungi Studies
  • Moringa oleifera research and applications
  • Mycotoxins in Agriculture and Food
  • Plant and Fungal Species Descriptions
  • Plant Disease Management Techniques
  • Microbial bioremediation and biosurfactants
  • Insect Pest Control Strategies
  • Plant Diversity and Evolution
  • Plant Pathogenic Bacteria Studies
  • Graphene and Nanomaterials Applications
  • Bee Products Chemical Analysis
  • Toxic Organic Pollutants Impact
  • Plant Disease Resistance and Genetics
  • Advanced Photocatalysis Techniques
  • Advanced Nanomaterials in Catalysis
  • Drug-Induced Hepatotoxicity and Protection
  • Plant Virus Research Studies
  • Microbial Metabolites in Food Biotechnology

King Saud University
2013-2025

Mae Fah Luang University
2025

Guizhou Institute of Technology
2024

Zhongkai University of Agriculture and Engineering
2024

Chiang Mai University
2024

University of Mauritius
2024

Guizhou University
2024

Guiyang Medical University
2024

The high prevalence of nosocomial bacterial resistance contributes to significant mortality and morbidity around the world; thus, finding novel antibacterial agents is vital concern. Accordingly, present study attempted synthesize silver nanoparticles (AgNPs) using a green approach. Aqueous leaf extract Origanum majorana was used AgNPs efficiency against multidrug resistant strains detected. Characterization biogenic performed ultraviolet-visible spectrophotometry (UV-Vis), transmission...

10.3390/cryst12050603 article EN cc-by Crystals 2022-04-25

Currently, nanoparticles and nanomaterials are widely used for biomedical applications. In the present study, silver (AgNPs) were successfully biosynthesized using a cell-free extract (CFE) of Bacillus thuringiensis MAE 6 through green ecofriendly method. The size AgNPs was 32.7 nm, their crystalline nature confirmed by XRD, according to characterization results. A surface plasmon resonance spectrum obtained at 420 nm. Nanoparticles further characterized DLS FTIR analyses, which provided...

10.3390/jfb13040242 article EN cc-by Journal of Functional Biomaterials 2022-11-15

Abstract One of the most promising, non-toxic, and biocompatible developments for many biological activities is green synthesis nanoparticles from plants. In this work, we investigated antifungal activity silver (AgNPs) biosynthesized Rhazya stricta aqueous extract against several plant pathogenic fungi. UV–visible spectroscopy, Zeta potential analysis, Fourier-transform infrared spectroscopy (FTIR), transmitted electron microscopy (TEM) were used to analyze AgNPs. Drechslera halodes,...

10.1038/s41598-024-51855-5 article EN cc-by Scientific Reports 2024-01-14

Biosynthesis of Ag@SeO 2 NC using turmeric extract with promising antibacterial and antioxidant properties, optimized AI, confirmed by various techniques.

10.1039/d4ra00004h article EN cc-by RSC Advances 2024-01-01

Cheeseweed mallow (Malva parviflora L.) was used to biosynthesize silver nanoparticles. The biosynthesized nanoparticles were classified by UV–vis Spectroscopy and Fourier-Transform Infrared (FT-IR). shape size distribution visualized Transmission Electron Microscopy (TEM), Field Emission Scanning (FE-SEM), Zeta potential analysis. chemical composition of M. leaf extract identified Gas Chromatography Mass (GC/MS). Finally, in vitro antifungal assay done assess the crude for inhibiting...

10.1016/j.sjbs.2021.01.012 article EN cc-by-nc-nd Saudi Journal of Biological Sciences 2021-01-26

The high incidence of fungal resistance to antifungal drugs represents a global concern, contributing levels morbidity and mortality, especially among immunocompromised patients. Moreover, conventional medications have poor therapeutic outcomes, as well possible toxicities resulting from long-term administration. Accordingly, the aim present study was investigate effectiveness biogenic zinc oxide nanoparticles (ZnO NPs) against multidrug-resistant candidal strains. Biogenic ZnO NPs were...

10.3390/cryst12060774 article EN cc-by Crystals 2022-05-26

The high frequency of nosocomial bacterial infections caused by multidrug-resistant pathogens contributes to significant morbidity and mortality worldwide. As a result, finding effective antibacterial agents is critical importance. Hence, the aim present study was greenly synthesize silver nanoparticles (AgNPs) utilizing Salvia officinalis aqueous leaf extract. biogenic AgNPs were characterized different physicochemical techniques such as energy-dispersive X-ray spectroscopy (EDX),...

10.3390/cryst12081057 article EN cc-by Crystals 2022-07-29

Nosocomial bacterial and fungal infections are one of the main causes high morbidity mortality worldwide, owing to prevalence multidrug-resistant microbial strains. Hence, study aims synthesize, characterize, investigate antifungal antibacterial activity silver nanoparticles (AgNPs) fabricated using Camellia sinensis leaves against nosocomial pathogens. The biogenic AgNPs revealed a small particle diameter 35.761 ± 3.18 nm based on transmission electron microscope (TEM) graphs negative...

10.3390/microorganisms11040945 article EN cc-by Microorganisms 2023-04-04

The effect of three independent variables (i.e., tyrosine, sucrose, and incubation time) on melanin production by Aureobasidium pullulans AKW was unraveled two distinctive approaches: response surface methodology (i.e. Box Behnken design (BBD)) artificial neural network (ANN) in this study for the first time ever using a simple medium. Regarding BBD, sucrose intervals did impose significant influence output (melanin levels), however, tyrosine not. validation process exhibited high...

10.1038/s41598-023-40549-z article EN cc-by Scientific Reports 2023-08-19

Due to increasing concerns about environmental impact and toxicity, developing green sustainable methods for nanoparticle synthesis is attracting significant interest. This work reports the successful of silver (Ag), silver-titanium dioxide (Ag@TiO

10.1016/j.heliyon.2024.e28359 article EN cc-by-nc Heliyon 2024-03-23

Proliferodiscus is a discomycete genus belonging to the family Lachnaceae (Helotiales). In present study, new species identified and introduced based on morphological characteristics multi-loci phylogenetic analyses of combined ITS LSU sequences. ailaoensis sp. nov. characterized by yellow creamy apothecia, white receptacle surface with bushy hairs, filiform, aseptate, unbranched paraphyses rounded apex, eight-spored, J- asci tapered pedicel, ascospores that are narrowly fusiform acute ends,...

10.11646/phytotaxa.682.3.3 article EN Phytotaxa 2025-01-22

Exposure to organophosphorus insecticides causes several health problems animals and humans. Red beetroot (RBR) is rich in antioxidant ingredients possesses a promising hepatoprotective activity. This study evaluated the potential of RBR extract prevent chlorpyrifos (CPF)-induced liver injury, with an emphasis on oxidative stress, inflammation apoptosis. Rats received 10 mg/kg CPF were treated 300 for 28 days. caused injury evidenced by elevated serum levels alanine aminotransferase (ALT),...

10.3390/biom9070261 article EN cc-by Biomolecules 2019-07-07

Grape seed extract (GSE) is a natural source of polyphenolic compounds and secondary metabolites, which have been tested for their possible antimicrobial activities. In the current study, we antibacterial antifungal activities aqueous GSE biosynthesized silver nanoparticles loaded with (GSE-AgNPs) against different pathogens. The GSE-AgNPs were assessed by UV spectroscopy, dynamic light scattering (DLS), field emission scanning electron microscopy (FE-SEM), transmission (TEM),...

10.3390/molecules26196081 article EN cc-by Molecules 2021-10-08

The green silver nanoparticles (green AgNPs) exhibit an exceptional antimicrobial property against different microbes, including bacteria and fungi. current study aimed to compare the antifungal activities of both crude aqueous extract Portulaca oleracea or preparations AgNPs biosynthesized by mixing that with nitrate (AgNO3). Two were synthesized either P. (AgNO3) (normal irradiation AgNPs, previously prepared, under 60Co γ-ray using chitosan (gamma-irradiated AgNPs). Characterization...

10.1016/j.sjbs.2021.12.056 article EN cc-by-nc-nd Saudi Journal of Biological Sciences 2022-01-03

Cucumber mosaic virus (CMV) causes a significant threat to crop output sustainability and human nutrition worldwide, since it is one of the most prevalent plant viruses infecting kinds plants. Nowadays, different types nanomaterials are applied as control agent against phytopathogens. However, their effects viral infections still limited. In current study, antiviral activities biosynthesized silver nanoparticles (Ag-NPs) mediated by aqueous extract Ocimum basilicum cucumber in squash...

10.3390/plants11202707 article EN cc-by Plants 2022-10-13

There is a crucial necessity for the formulation of efficient antimicrobial agents owing to increasing prevalence hospital-acquired bacterial infections triggered by multidrug-resistant microbes that result in significant deaths and illnesses around world. Hence, current investigation examined antibacterial proficiency zinc oxide nanoparticles formulated utilizing green route against strains were resistant multiple drugs. In addition, synergistic action ZnO (ZnO NPs) combined with colistin...

10.3390/cryst12111513 article EN cc-by Crystals 2022-10-25

Bioactive compounds extracted from marine organisms showed several biological activities. The present study is an extension of our earlier studies where we assessed the antiproliferative and pro-apoptotic activities ethanol, methylene chloride, ethyl acetate, acetone, chloroform crude extracts sponges: Negombata magnifica (NmE) Callyspongia siphonella (CsE) against cancer cells. Herein, are extending previous findings on both sponge species depending alternative methanol extraction method...

10.3390/app12031400 article EN cc-by Applied Sciences 2022-01-28

The synthesis of novel nanomedicines through eco-friendly protocols has been applied on a large scale with the prediction discovering alternate therapies. current work attained phytogenic Ag-mNPs, AgSeO2-bmNPs, and Ag-TiO2-bmNPs bio-reduction using an aqueous extract Beta vulgaris (red beetroot). phytochemical profile synthesized metallic/bimetallic nanoparticles was studied. optical properties nano-solutions were studied via UV-visible spectroscopy. Fourier-transform infrared spectroscopy...

10.3390/app131810110 article EN cc-by Applied Sciences 2023-09-08

Capsicum is a common spice used in food flavouring. However, they are prone to mycotoxin contamination. Mycotoxins natural toxins produced by filamentous fungi and can pose serious risks human health. Fungal contamination was assessed 130 randomly collected samples following ISO 21527–2:2008 standards. Results revealed that 84.6% of the exceeded acceptable fungal count limit (102 CFU/g) according Gulf Cooperation Council (GCC) standards (GSO1016:2015). The predominant isolates were...

10.1016/j.foodcont.2024.110377 article EN cc-by Food Control 2024-03-08

Consumer demand for plant-based alternatives drives innovation in nondairy beverages. This study explores the development of a novel sesame milk with enhanced functionality using an artificial neural network (ANN) and permeate integration. An ANN model effectively optimized water-based (WSM) extraction, maximizing total solids (T.S.) recovery. The model's predicted T.S. yield (99.65%) closely matched actual value (95.18%), demonstrating its potential optimizing high-yield production....

10.1021/acsomega.4c02824 article EN cc-by-nc-nd ACS Omega 2024-05-29

The green biosynthesis of nanoparticles by plant extracts is an attractive and promising technique for medicinal applications. In the current study, we chose one daisy plants, Aaronsohnia factorovskyi (which grows in Najd region, Saudi Arabia), to investigate its anti-microbial efficacy, combination with silver nanoparticles. biosynthesized were evaluated antibacterial activity against Staphylococcus aureus, Bacillussubtilis (Gram-positive), Pseudomonas aeruginosa, Escherichia coli,...

10.3390/molecules26010130 article EN cc-by Molecules 2020-12-30

The use of synthetic azo dyes as coloring agents in food products has dramatically increased. This study evaluated the effect perinatal exposure to tartrazine (TZ) on mice offspring, focusing neurobehavioral alterations and oxidative stress. female received TZ (2.5 5 mg/kg) via oral gavage during pregnancy first 15 days after birth. At 21 35 birth, male were sacrificed, samples collected for analyses. Perinatal triggered tissue injury evidenced by histological neuronal damage cerebrum,...

10.3390/antiox9010053 article EN cc-by Antioxidants 2020-01-08

The drug resistance of bacterial pathogens causes considerable morbidity and death globally, hence there is a crucial necessity for the development effective antibacterial medicines to address issue. bioprepared zinc oxide nanoparticles (ZnO-NPs) were prepared utilizing flower extract Hibiscus sabdariffa then characterized using different physicochemical techniques. effectiveness ZnO-NPs their synergism with fosfomycin evaluated disk diffusion assay against concerned pathogens. Transmission...

10.3390/microorganisms11030645 article EN cc-by Microorganisms 2023-03-02

The current study focused on the green synthesis of iron oxide nanoparticles (IONPs) using Salvia officinalis leaf extract, aiming to control nosocomial infections caused by drug-resistant bacterial pathogens. were characterized and evaluated for antibacterial effectiveness. disc diffusion assay was utilized determine synergistic efficiency biogenic IONPs against three pathogens namely, methicillin-resistant Staphylococcus aureus (MRSA), Escherichia coli Pseudomonas aeruginosa strains....

10.1016/j.jksus.2024.103131 article EN cc-by-nc-nd Journal of King Saud University - Science 2024-02-08
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