A5088575576- Antibiotic Resistance in Bacteria
- Salmonella and Campylobacter epidemiology
- Antimicrobial Resistance in Staphylococcus
- Antibiotic Use and Resistance
- Bacterial biofilms and quorum sensing
- Microbial Metabolism and Applications
- Pharmaceutical and Antibiotic Environmental Impacts
- Bacteriophages and microbial interactions
- Listeria monocytogenes in Food Safety
- Genomics and Phylogenetic Studies
- Pharmaceutical Quality and Counterfeiting
- Viral gastroenteritis research and epidemiology
- Mycotoxins in Agriculture and Food
- Wheat and Barley Genetics and Pathology
- Dental Research and COVID-19
- Animal Virus Infections Studies
- Antibiotics Pharmacokinetics and Efficacy
- Infection Control in Healthcare
- Agriculture, Plant Science, Crop Management
- Healthcare and Environmental Waste Management
- Food Safety and Hygiene
- Antifungal resistance and susceptibility
- Plant Pathogens and Resistance
- Pharmaceutical Economics and Policy
- Drug-Induced Adverse Reactions
Saudi Arabian Monetary Authority
2021-2025
Capsicum is a common spice used in food flavouring. However, they are prone to mycotoxin contamination. Mycotoxins natural toxins produced by filamentous fungi and can pose serious risks human health. Fungal contamination was assessed 130 randomly collected samples following ISO 21527–2:2008 standards. Results revealed that 84.6% of the exceeded acceptable fungal count limit (102 CFU/g) according Gulf Cooperation Council (GCC) standards (GSO1016:2015). The predominant isolates were...
Objectives Staphylococcus aureus is a leading cause of hospital acquired infections worldwide. Over recent decades, methicillin resistant (MRSA), which to multiple antimicrobials, has emerged as significant pathogenic strain in both and community settings. The rapid emergence dissemination MRSA clones are driven by dynamic evolving population, spreading swiftly across regions on epidemiological time scales. Despite the vast geographical expanse diverse demographics Kingdom Saudi Arabia...
Salmonella enterica serovar Minnesota (S. Minnesota) is an emerging that persists within poultry supply chains, potentially causing outbreaks in humans. Understanding its population genomics crucial for designing preventive measures. We performed a genomic surveillance study of S. by analyzing 259 isolates from Saudi Arabia. Whole-genome sequencing data these were analyzed to characterize clones and the genetic factors underlying antimicrobial resistance virulence. compared all available...
The incidence of hospital- and community-acquired infections has been dramatically increased worldwide. Accordingly, hands hygiene the use disinfectants have leading to expansion in hand sanitizers production meet public demand. This study was conducted assess efficiency common market Riyadh, Saudi Arabia inhibiting microbial growth during time Coronavirus disease 2019 (COVID-19) pandemic. Five bacterial strains commonly hospital-acquired ( Pseudomonas aeruginosa , Escherichia coli...
Introduction Staphylococcus aureus is a significant human pathogen that poses threat to public health due its association with foodborne contamination and variety of infections. The factors contributing the pathogenicity S. include virulence, drug resistance, toxin production, making it essential monitor their prevalence genetic profiles. This study investigated compared genomic characteristics isolates from retail meat patients in Saudi Arabia. Methods A total 136 were obtained between...
Abstract Escherichia coli O157:H7 is a foodborne pathogen, which causes various health conditions in humans, including fatigue, nausea, bloody diarrhoea and some cases, even death. In 2017, 15.71% of the total imported food products Saudi Arabia (SA) were meat-based. India Brazil are two top five countries from where SA imports meat. According to Food Drug Authority, at least 562, 280, 50 samples beef, chicken sheep meat, respectively, tested for presence E. O157:H7. Amongst these, was...
Quorum sensing inhibitor (QSI) has been attracting attention as anti-virulence agent which disarms pathogens of their virulence rather than killing them. QSI marking cyclic peptide-mediated QS in Gram-positive bacteria is an effective tool to overcome the crisis antibiotic-dependent chemotherapy due emergence drug resistance strain, e.g., methicillin resistant Staphylococcus aureus (MRSA) and Vancomycin Enterococci (VRE). From a semi-large-scale screening thus far carried out, two Epoxide...
In this study, we investigated both meat-derived and methicillin-resistant Staphylococcus aureus (MRSA), exploring their genetic relatedness to patient-derived MRSA isolates in Saudi Arabia. We collected 250 meat samples identified 53 S. isolates, with 79% being methicillin-sensitive (MSSA) 21% MRSA. Moreover, included 80 clinically confirmed isolates. the most common clone patients retail meat. meat, ST6 ST97 were clones 55% of ST1153 ST672 17% MSSA patients, ST5 predominant 46%...
Valley surface water is considered a focal public health concern owing to the presence of multi-drug-resistant bacteria. The distribution antimicrobial resistance (AMR) bacteria in affected by multiple factors, including antibiotics coming from wastewater discharge or other contaminant sources such as pharmaceuticals, biocides, and heavy metals. Furthermore, there evidence suggesting that high levels antibiotic genes (ARGs) can be transferred within bacterial communities under influence...
Salmonella has been reported as a high-priority pathogen by the World Health Organization. Here, we report draft genome sequence of 2 enterica serovar Minnesota strains isolated from chicken meat in Saudi Arabia (named SA49317 and SA49319) belonging to type (ST) 548, revealing mobile colistin resistance (mcr)-1.1 gene for resistance.
Antimicrobial dispensing without a prescription has been identified as significant contributor to the burgeoning crisis of antimicrobial resistance. To combat this, Saudi Ministry Health introduced stringent restriction policy in mid-2018, mandating prescriptions for all drug dispensations at pharmacies. Therefore, this study aimed assess immediate impact on retail sales. do so, we analyzed annual sales data from 2017 2019 sourced IQVIA-MIDAS® database, which included range antimicrobials,...
The recent emergence and dissemination of mobilized colistin resistance ( mcr ) genes have triggered extensive concerns globally. Here, we report the complete genome sequence a colistin-susceptible Salmonella enterica serotype Minnesota strain (named SA18578), belonging to type 548 (ST548) carrying mcr-9 gene on an IncHI2/IncHI2A plasmid, that was isolated from chicken meat in Saudi Arabia 2020.
Klebsiella pneumoniae is a Gram-negative bacterium associated with wide range of community- and hospital-acquired infections. The emergence clonal hypervirulent strains resistant to last-resort antimicrobial agents has become global concern. Kingdom Saudi Arabia (KSA), its diverse population high tourism traffic, serves as platform where the spread multidrug-resistant (MDR) are facilitated. However, knowledge epidemiology diversity MDR K. in KSA scarce. We conducted comprehensive genomic...
Milk is susceptible to Aflatoxin M1 (AFM1) contamination, mainly through consumption of contaminated animal's feed. The natural occurrence aflatoxin (AFB1) has been surveyed in samples milk and powder. Samples collected from different regions Saudi Arabia during the period 2013 2021 were subjected high-performance liquid chromatography analysis, was quantified with detection limits 0.5 µg/kg. Food Drug Authority taken strong actions limit AFM1 increase control, modify regulations. A study...
Abstract The Gram-negative bacterium Klebsiella pneumoniae is a major human health threat underlying broad range of community- and hospital-associated infections. emergence clonal hypervirulent strains often resistant to last-resort antimicrobial agents has become global burden as treatment options are limited. Kingdom Saudi Arabia (KSA) dynamic diverse population serves tourist hub facilitating the dissemination multidrug-resistant (MDR) K. . To examine spread clinically relevant strains,...
Abstract Background Salmonella enterica serovar Minnesota ( S . Minnesota) is an emerging of non-typhoidal , known to persist in the food chain and distribution systems, potentially leading outbreaks infections human settings. Understanding population genomics dynamics this pathogen key designing preventative measures containing its spread within poultry production chain. Methods In study, we conducted a large-scale study on outbreak by fully characterizing diversity systematic collection...
Vegetables are an essential component of a balanced diet. The consumption ready-to-eat foods may lead to the risk infections and illnesses due microbial contamination. To mitigate potential contamination risks, it is critical promote safe handling practices among consumers. In this study, our research evaluated efficacy different vegetable washing methods, specifically with lettuce, tomato, cucumber, establish optimal for reducing This study consisted two phases. Initially, survey was...
Abstract Background: Antimicrobials dispensing without a prescription is recognized as pathway for the emergence of antimicrobial resistance; serious global public health issue in need urgent regulatory responses. In mid-2018, Saudi Ministry Health initiated nationwide restriction policy, which pharmacies are strictlyprohibited from drugs physicians’ prescription. Therefore, objective this study was to determine if policy implemented by has led decrease sales. Methods: The annual retail...
Background: Understanding antibiotic consumption patterns over time is essential to optimize prescribing practices and minimizing antimicrobial resistance. This study aimed determine whether the antibiotics restriction policy launched by Saudi Ministry of Health in April 2018 has impacted use assessing changes seasonal variations following enforcement. Methods: Quarterly sales data J01 antibacterial for systemic standard units were obtained from IQVIA-MIDAS database, spanning first quarter...
Abstract Hospitals and communities are significant hubs for antibiotic-resistant staphylococcal infections, but recently there have been spread of the Staphylococci to other settings including farms food chains. This study aimed compare methicillin-resistant Staphylococcus aureus (MRSA) isolates from humans understand genetic characteristics similarities between circulating clones across both groups. A total 250 samples meat (camel, beef, chicken, fish, lamb) were collected different...