A5024781185- Extracellular vesicles in disease
- MicroRNA in disease regulation
- Effects and risks of endocrine disrupting chemicals
- Carcinogens and Genotoxicity Assessment
- RNA Interference and Gene Delivery
- RNA regulation and disease
- Immunotherapy and Immune Responses
- Toxic Organic Pollutants Impact
- Cancer Research and Treatments
- Circular RNAs in diseases
- Cutaneous Melanoma Detection and Management
- Cancer, Hypoxia, and Metabolism
- Plant Molecular Biology Research
- Redox biology and oxidative stress
- Nanoplatforms for cancer theranostics
- Agricultural safety and regulations
- Lipid Membrane Structure and Behavior
- Connexins and lens biology
- melanin and skin pigmentation
- Circadian rhythm and melatonin
- Light effects on plants
- Immune cells in cancer
- CAR-T cell therapy research
- Cancer, Stress, Anesthesia, and Immune Response
ExxonMobil (United States)
2022-2024
Rutgers, The State University of New Jersey
2013-2023
Concawe
2022
Environmental and Occupational Health Sciences Institute
2016
The circadian oscillator controls time-of-day gene expression by a network of interconnected feedback loops and is reset light. requisite for chromatin regulation in eukaryotic transcription necessitates temporal histone-modifying chromatin-remodeling enzymes proper clock function. CHD1 known to bind H3K4me3 mammalian cells, Neurospora required the frequency (frq) gene. Based on this, we examined strain lacking SET1 determine role H3K4 methylation clock- light-mediated frq regulation....
The carcinogenicity and developmental toxicity of unrefined mineral oil is related to its 3-7 ring polycyclic aromatic compounds (PAC) content. Therefore, refining operations focus on the targeted removal PAC from that may contain aromatics low toxicological concern. There are thus, two types substances in oil: hazardous non-hazardous. first type consists which be naked (unsubstituted) or lowly alkylated. second non-hazardous 1-7 with high degree alkylation lack bay fjord regions. Although...
// Allison L. Isola 1, 2 , Kevinn Eddy 1 Krzysztof Zembrzuski James S. Goydos 3 and Suzie Chen 2, Susan Lehman Cullman Laboratory for Cancer Research, Ernest Mario School of Pharmacy, Rutgers, The State University, Piscataway, NJ 08854, USA Joint Graduate Program in Toxicology, Rutgers Institute New Jersey, Brunswick, 08901, Correspondence to: Chen, email: suziec@pharmacy.rutgers.edu Keywords: exosomes; GPCR; melanoma; GRM1; cancer Received: May 10, 2017 Accepted: December 08, Published: 19,...
122 Background: GRM1 transgenic mice in an immune competent background (C57BL6) develope melanoma with 100% penetrance (TG-3 mice). Ectopic expression of immortalized mouse melanocytes (MelanA) produce cells (MASS20) that are tumorigenic both SCID and C57BL6 mice. We have examined the downstream events signaling allow transformed to evade destruction. Methods: Cytokine antibody arrays Western blot were used examine differences cytokine between MASS20 parental controls. Next, we cultured bone...
Abstract Hazard and risk assessment of complex petroleum-derived substances has been in a state continuous improvement since the 1970s, with development approaches that continue to be applied refined. Alternative feeds are defined here as those coming into refinery or chemical plant not hydrocarbons from oil gas extraction such biologically derived oils, pyrolysis biomass other, recycled materials. These increasingly being used for production liquid hydrocarbon streams, hence, there is need...
Abstract Exosomes are naturally occurring small membrane enclosed microvesicles generated constitutively and released by various cell types more frequently tumor cells. It was postulated that exosomes may facilitate communication within the local microenvironment primary tumor, supporting melanoma dissemination early events in metastasis. A gain-of-function mutation of a neuronal receptor, metabotropic glutamate receptor 1 (GRM1), when ectopically expressed melanocytes, sufficient to induce...