A5102709590- Glaucoma and retinal disorders
- Ocular Surface and Contact Lens
- Corneal surgery and disorders
- Corneal Surgery and Treatments
L V Prasad Eye Institute
2018-2021
Purpose Pseudoexfoliation (PXF) is a unique form of glaucoma characterized by accumulation exfoliative material in the eyes. Changes tear profile disease stages may give us insights into molecular mechanisms involved causing eye. Methods All patients were categorized three main categories; pseudoexfoliation (PXF), (PXG) and cataract, which served as control. Cytokines, transforming growth factor β1 (TGFβ1), matrix metalloproteases (MMPs) fibronectin (FN1) assessed with multiplex bead assay,...
Purpose Prostaglandin analogues (PGA’s) are the mainstay and first line of treatment in current glaucoma practise. Though latanoprost bimatoprost most commonly used PGA’s with minimal side effects at lower concentrations like bimaotoprost 0.01%, direct comparison their cytokine/MMP profile tears has not been evaluated earlier. The study intends to ascribe PGA upregulation MMPs, Cytokines Chemokines mediating varied pathways result drugs. Methods Tear sample collection was done from outer...