A5080432192- 3D Printing in Biomedical Research
- Microfluidic and Capillary Electrophoresis Applications
- Electrochemical sensors and biosensors
- Nanofabrication and Lithography Techniques
- Advanced Sensor and Energy Harvesting Materials
- Advanced MEMS and NEMS Technologies
- Advancements in Transdermal Drug Delivery
- Electrowetting and Microfluidic Technologies
- Neuroscience and Neural Engineering
- Pancreatic function and diabetes
- Cellular Mechanics and Interactions
- Hydrogels: synthesis, properties, applications
- Diabetes Management and Research
- Ocular Surface and Contact Lens
- Analytical Chemistry and Sensors
- Innovative Microfluidic and Catalytic Techniques Innovation
- Piezoelectric Actuators and Control
- Muscle activation and electromyography studies
- Wireless Body Area Networks
- Metallurgy and Material Forming
- Liver physiology and pathology
- Advanced biosensing and bioanalysis techniques
- Microfluidic and Bio-sensing Technologies
- Interactive and Immersive Displays
- Innovative Energy Harvesting Technologies
Kyung Hee University
2017-2025
Gyeongsang National University
2024
Samsung (South Korea)
2022
Health Insurance Review and Assessment Service
2020
Tokyo University of Agriculture and Technology
2013-2016
The University of Tokyo
2007-2015
Japan Science and Technology Agency
2012-2015
University of Illinois Urbana-Champaign
2015
Korea Advanced Institute of Science and Technology
2007-2012
Global College
2012
The use of fluorescence-based sensors holds great promise for continuous glucose monitoring (CGM) in vivo, allowing wireless transdermal transmission and long-lasting functionality vivo. ability to monitor concentrations vivo over the long term enables be implanted replaced less often, thereby bringing CGM closer practical implementation. However, full potential long-term has yet realized because current cannot remain at an implantation site respond blood extended period. Here, we present a...
Fluorescent microbeads hold great promise for in vivo continuous glucose monitoring with wireless transdermal transmission and long-lasting activity. The full potential of fluorescent has yet to be realized due insufficient intensity material toxicity. This paper illustrates the highly-sensitive, biostable, long-lasting, injectable monitoring. We synthesized a monomer composed glucose-recognition sites, fluorogenic site, spacers, polymerization sites. spacers are designed long hydrophilic...
Continuous glucose monitoring (CGM) allows patients with diabetes to manage critical disease effectively and autonomously prevent exacerbation. A painless, wireless, compact, minimally invasive device that can provide CGM is essential for the health conditions of freely moving diabetes. Here, we propose a glucose-responsive fluorescence-based highly sensitive biodegradable microneedle system. These ultrathin ultralight sensor arrays continuously precisely monitored concentration in...
This study introduces a facile method for fabricating hydrophilic 3D-network hydrogels, integrating plasmonic gold nanoparticles to boost solar absorption, enhancing evaporation rates and efficiency 1.6 kg m −2 h −1 77%, respectively.
Abstract This paper describes a theoretical estimation of the geometry negative epoxy-resist microneedles prepared via inclined/rotated ultraviolet (UV) lithography based on spatially controlled UV exposure doses. In comparison with other methods lithography, present method can create microneedle structures high scalability. When photoresist is exposed to through circular mask patterns, three-dimensional, needle-shaped distribution dose forms in irradiated region. Controlling inclination...
Continuous glucose monitoring (CGM) sensors have led a paradigm shift to painless, continuous, zero-finger pricking measurement in blood monitoring. Recent electrochemical CGM reached two-week lifespans and no calibration with clinically acceptable accuracy. The system the recent is identified as an “integrated system,” which can replace finger-pricking glucose-testing for diabetes treatment decisions. Although such innovation has brought technology closer realizing artificial pancreas,...
Hypoxia plays an essential role in the pathogenesis of various liver diseases, and albumin is one important biomarkers secreted by liver. In this study, we developed monitoring system composed hepatic hypoxia-on-a-chip sensor to study function change due hypoxia. hypoxia-on-a-chip, vertically stack oxygen-scavenging channel on a chip with thin gas-permeable membrane middle. This unique design can help induce hypoxia quickly, attaining <5% within 10 min. An electrochemical was fabricated...
In this study, we present the development of an innovative electrochemical biosensor integrated into a microneedle-based system for non-invasive and sensitive quantification cholesterol levels in interstitial fluid (ISF). The employs graphene-based electrode with polyelectrolyte interlayer to immobilize oxidase (ChOx), enabling selective detection. Graphene oxide is electrochemically reduced form conductive layer, PANI chosen as optimal ChOx immobilization. biosensor's performance thoroughly...
We propose a simple, fast, height-scalable, and direct way to fabricate highly biocompatible polyethylene glycol diacrylate (PEGDA) microneedles. A needle-shaped distribution of ultraviolet (UV) exposure dose is formed in PEGDA by applying UV light through rotating prism. prism makes rays bend, such that the base angle determines inclined light. Thus, microneedle height can be controlled varying angles experimentally demonstrate height-scalable potential. The decreases tip increases with...
This paper describes a liquid-filled tunable lenticular lens for switching between two-dimensional (2D) and three-dimensional (3D) images in naked-eye 3D displays. Compared with previous 2D/3D switchable displays, this that is directly attached to smartphone display can project both 2D image the original resolution of high brightness. simply composed transparent poly(dimethylsiloxane) (PDMS) microchannels. While thin top membrane on microchannels normally flat transmit light without...
This work presents self-focusing 3D lithography based on the refractive index changes of polyethylene glycol diacrylate (PEGDA) during photopolymerization. Since polymerization PEGDA leads to an increase in index, UV light rays undergo a refraction effect exposure, thus being focused and forming photopolymerized structures. We demonstrate potential by fabricating microneedles trapezoid-shaped microwells. Their structures well match our theoretical estimation. Therefore, approach can provide...
Correcting errors in DNA sequencing data is an important process that can improve the quality of downstream analysis using data. Even though many error-correction methods have been proposed for Illumina reads, their throughput not high enough to from large genomes. The current paper describes first FPGA-based tool, called FPGA Accelerated Error Correction (FADE), which targets error correction reads. base algorithm FADE BLESS highly accurate but slow. A Bloom filter main structure and BLESS'...
We present fluorescent Janus hydrogel microbeads for continuous glucose sensing with pH calibration. The microbeads, that consist of and sensors, were fabricated a UV-assisted centrifugal microfluidic device. microbead can calibrate the values its surroundings enables accurate measurements within various conditions. As proof concept, we succeeded in obtaining value concentration body-fluid-like sample solution. believe our calibration capability, could be applied to fully implantable sensors...
Abstract Men’s sexual health can have significant effects on a man’s self-esteem, relationship and male reproductive functions. Although commercially available drugs (e.g., VIAGRA CIALIS) show effective treatment of erectile dysfunction (ED), patients with severe ED fail to respond these medicines. Topical nitric-oxide (NO) delivery penis be painless, alternative solution because NO triggers erection diffuses the trabecular arteries smooth muscles in penis. We here develop water-in-oil (W/O)...
Microenvironmental biophysical stimuli influence diverse cellular functions, such as directional motility and stem cell differentiation. Previously, researchers have tuned the linear stiffness of microposts to investigate mechanobiological processes direct behavior; however, suffer from an inherent, yet critical drawback - regulation micropost is fundamentally limited "biaxial" control. To overcome this issue, here we utilize three-dimensional (3D) direct-write laser lithography fabricate...
This paper describes a simple and rapid process for the fabrication of 3D solid microstructures. We combined conventional two-photon direct laser writing with Parylene coating process. Two-photon allows us to make arbitrary nano / micro structures, but it takes long time draw structure because scans inside photo-sensitive materials. Here, we deposited on wire frame fill gap between wires. rapidly form surface structures. Our method can fabricate cube 100 μm × 40 20 times faster compared writing.
We propose a biomedical sensor system for continuous monitoring of glucose concentration. Despite recent advances in implantable devices, mm sized devices have yet to be developed due the power limitation device tissue. here present wireless with backscattered frequency-modulation communication that enables low-power operation read level from fluorescent hydrogel sensor. The configuration reader structure is optimized an efficient transfer and data communication, miniaturizing entire 3 × 6 2...