The aim of this study was to see the clinical, pathological, and demographic profile young patients with stomach carcinoma besides association p53. Prospective from January 2005 December 2009. A total 50 age less than 40 years were studied. Male female ratio 1 : 1.08 in 2.5 older patients. positive family history cancer first degree relatives present 10% Resection possible only 50% 26% underwent palliative gastrojejunostomy. most common operation lower partial gastrectomy 68%. Amongst...

There is still confusion and controversy over the diagnosis optimal surgical treatment of non traumatic terminal ileal perforation-a cause obscure peritonitis.This study was a prospective aimed at evaluating clinical profile, etiology management patients with nontraumatic perforation.There were 79 cases perforation; causes for perforation enteric fever(62%), nonspecific inflammation(26%), obstruction(6%), tuberculosis(4%) radiation enteritis (1%). Simple closure (49%) end to side...

The aim of this study was to investigate the role XRCC1 Arg399Gln polymorphism in susceptibility a Kashmiri population colorectal cancer (CRC). We investigated genotype distribution gene 130 CRC cases comparison with that 150 healthy subjects. There no direct significant association between genotypes and CRC; however, Arg/Gln associated an elevated risk (OR>1.47) Gln/Gln variant increased various clinicopathological parameters. This suggests is CRC.

Abdominal organ injury in a primary blast type is always challenging for diagnosis. Air containing abdominal viscera most vulnerable to effects of injury. In any patient exposed wave who presents with an acute abdomen, be kept clinical suspicion. Study various injuries occurring Material and methods: All those had exploratory laparotomy after period 10 years from January 1998 - 2008 were included this retrospective study. Total 154 patients Small intestine was damaged 48 (31.1%) followed by...

Hydatid disease is a cyclo­zoonotic parasitic infection caused by Echinococcus granulosus. This usually found in liver and lungs but no organ of body immune. Location at unusual sites the can have atypical presentations pose diagnostic challenge. A high index suspicion, radiological investigations as well histopathological examination necessary establishing diagnosis hydatid body. We present review occurrence our experience with clinical presentation management disease.

Abstract Background Primary squamous cell carcinomas of the colorectum are very uncommon. Until now, to best our knowledge, only 114 cases carcinoma in exist reported literature. Here we report a case rectum ethnic Kashmiri population northern India. Case Presentation The 60-year-old male patient (Asian) with pure is presented here. underwent curative surgery concomitant chemotherapy. Two years after initial resection tumor he still alive. Conclusion prognosis for worse than that...

This is a case report of young man who presented to us as hypogastric pain and frequency micturation. General physical examination radiological evaluation confirmed multiloculated pelvic swelling. Patient was subjected laparotomy which the diagnosis primary hydatid disease. put on chemotherapy after surgery doing well follow up.

Breast gangrene is rare in surgical practice. Gangrene of breast can be idiopathic or secondary to some causative factor. Antibiotics and debridement are used for management. Acute inflammatory infiltrate, severe necrosis tissue, necrotizing arteritis, venous thrombosis observed on histopathology. The aim was study patients who had gangrene. A prospective 10 over a period 6 years were analyzed All the group female. Total encountered Six presented with right whereas four left breast. Out...

Aerobic glycolysis is the hallmark of many cancer cells that results in a high rate adenosine triphosphate (ATP) production and, more importantly, biosynthetic intermediates, which are required by fast-growing tumor cells. The molecular mechanism responsible for increased glycolytic influx still not fully understood. In present study, we have attempted to address above question exploring role enzyme, triose-phosphate isomerase (TPI), western blot analysis 30 human colorectal samples depicted...

Connexin 43 is an important gap junction protein in vertebrates and known for its tumor suppressive properties. Cx43 abundantly expressed the human intestinal epithelial cells muscularis mucosae. To explore role of genesis colon cancer, we performed expression analysis 80 cases histopathologically confirmed clinically diagnosed cancer samples adjacent control tissue assessed correlations with clinicopathological variables. Western blotting using anti-Cx43 antibody indicated that was...

ABSTRACT Background: Mechanical bowel preparation (MBP) of gut is routinely done before colorectal surgeries in most surgical departments all over the globe. This aimed at reducing risk postoperative infections patients undergoing surgery. Even though recent studies are more favor operating on without preparation, controversies still exist. The aim our study was to assess whether elective can be performed safely preoperative MBP. Methods: Patients were prospectively randomized into two...

A young female presented with classical complaints suggestive of peptic ulcer disease leading to signs peritonitis. The said patient after being subjected baseline workup was laparotomy which proved be a surgical surprise. live ascaris lumbricoides worm seen pouting out duodenal perforation.

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The present study aimed to analyse the role of cyclin D1 A870G polymorphism in modulating susceptibility colorectal cancer (CRC) Kashmiri population. genotype distribution gene 130 CRC cases comparison with 160 healthy controls was investigated. No direct significant association between genotypes and observed; however, AG AA were found be associated an increased risk compared GG genotype, almost 2-fold increase OR. This suggests that is

Abstract Hemorrhoids are the most common anorectal disorders with a prevalence of 39% in general population. generally classified on basis their location and degree prolapse. Goligher’s classification does not describe number hemorrhoidal columns involved give much consideration to amount blood loss. To disease more vividly, we devised “PNR-Bleed” (or PNR-Booking) system. We tried classify hemorrhoids based four main characteristics i.e. Prolapse (P), Number (N) primary involved, Relation...

Background: Colorectal cancer is the third most common type of worldwide. It more prevalent in elderly age group. Genetic and environmental factors play a role. Extent lymph node dissection determines prognosis overall survival patient. Methods: This study was conducted colorectal division Department General minimal invasive surgery SKIMS Soura from June 2020 to May 2023. prospective comprising 55 patients. The patients were studied two groups: D2 D3, compared on basis group, gender,...