A5051114808- Acute Myeloid Leukemia Research
- Neuroinflammation and Neurodegeneration Mechanisms
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Cytokine Signaling Pathways and Interactions
- Acute Lymphoblastic Leukemia research
- Platelet Disorders and Treatments
- Natural Compounds in Disease Treatment
- Glioma Diagnosis and Treatment
- Chronic Myeloid Leukemia Treatments
Tianjin Medical University General Hospital
2022-2024
Objective Immune thrombocytopenia (ITP) is an autoimmune hemorrhagic disease. The immune imbalance of T cells essential pathological mechanism ITP, more specific, the balance Effector (Teff)/Regulatory cell (Treg) maintains homeostasis. Dendritic (DC), largest antigen-presenting cell, interfere with differentiation pathways and exert regulatory functions. Our team created applied “ NingXueShengBan” (NXSB) decoction. According to our prior studies, we found that NXSB decoction could restore...
Abstract Background : Aplastic anemia (AA) is an immune-mediated disease of bone marrow failure owing to activated cytotoxic T lymphocytes (CTLs). CD4+CD25+ regulatory cells (Tregs) could negatively regulate CTLs maintain self-tolerance and avoid excessive immune responses. This study aims investigate the effect Dioscin on functions Tregsin AA mouse model, which were induced by total body irradiation allogeneic lymphocyte infusion. Methods Results The collected CD4+CD25+Tregs randomly...