A5022093107- Bioactive Compounds and Antitumor Agents
- Nigella sativa pharmacological applications
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Phytochemistry and Bioactivity Studies
- Effects of Radiation Exposure
- Adenosine and Purinergic Signaling
- Cardiovascular Disease and Adiposity
- Synthesis and Characterization of Heterocyclic Compounds
- Exercise and Physiological Responses
- Hydrogen's biological and therapeutic effects
- Inflammatory Biomarkers in Disease Prognosis
- Tryptophan and brain disorders
- Reproductive System and Pregnancy
- Epigenetics and DNA Methylation
- Synthesis and Reactions of Organic Compounds
- Anesthesia and Sedative Agents
- Reproductive Biology and Fertility
- Intensive Care Unit Cognitive Disorders
- Synthesis and biological activity
- Therapeutic Uses of Natural Elements
- Dietary Effects on Health
- Intracranial Aneurysms: Treatment and Complications
- Infrared Thermography in Medicine
- Medical and Biological Ozone Research
- Hippo pathway signaling and YAP/TAZ
Sağlık Bilimleri Üniversitesi
2022-2025
Istanbul University
2022-2025
Haydarpaşa Numune Eğitim ve Araştırma Hastanesi
2025
University of Health Sciences Antigua
2023-2024
University of Health Sciences
2023
Aim: The aim of this study was to compare the effects dexmedetomidine, midazolam, propofol, and intralipid on lidocaine-induced cardiotoxicity neurotoxicity. Methods: Forty-eight male Sprague-Dawley rats were randomly divided into six groups (n = 8 per group): control (C), lidocaine (L), + dexmedetomidine (LD), midazolam (LM), propofol (LP), (LI). Dexmedetomidine (100 μg/kg), (4 mg/kg), (40 (10 mg/kg) administered intraperitoneally as pretreatment. Lidocaine (90 induce oxidative stress in...
BACKGROUND Ligamentum flavum (LF) hypertrophy is a key contributor to spinal pathologies such as lumbar and cervical disc herniations stenosis. Smoking, modifiable lifestyle factor, implicated in systemic inflammation oxidative stress, potentially exacerbating LF hypertrophy. This study aimed compare the expression of alpha-1 antitrypsin (AAT), interleukin-1 beta (IL-1 beta), interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-alpha) ligamentum from 27 smokers 31 non-smokers. MATERIAL AND...
<title>Abstract</title> Background Spontaneous subarachnoid hemorrhage (SAH) is a severe neurological condition with significant morbidity and mortality. Cerebral vasospasm, common complication of SAH, leading cause delayed ischemic injury. Oxidative stress inflammation are central to the pathophysiology vasospasm. Vitamin B12, water-soluble vitamin antioxidant anti-inflammatory properties, has shown potential neuroprotective effects in experimental models. Objectives This study aimed...
Introduction Prostate Cancer (PC) is a global health concern affecting men worldwide. Oxidative stress believed to contribute the initiation of early-stage PC lesions. Additionally, inflammation has long been acknowledged as factor in development PC. We aimed examine biomarkers oxidative and patients before after surgery.
Objective. The pathophysiology of fibromyalgia (FM), a continuously painful syndrome with no known origin, has been related to mitochondrial dysfunction, oxidative stress, and inflammation. Recent studies have shown that FM may be associated an balance disorder. objective this study was measure the levels stress in patients try understand association between free radicals. Methods. This performed on 100 volunteers admitted University Health Sciences, Sultan 2, Abdulhamid Han Application...
Abstract Intro : Thymoquinone(TQ), a compound derived from Nigella sativa , has been found to impede cancer progression, including proliferation, migration, and invasion. Previous research explored the potential benefits of augmenting TQ with functional groups enhance its activity, particularly when combined traditional drugs. The aim our study was investigate therapeutic effects Thymoquinone‐Oxime(TQ−Ox) on lung cell lines. Methods To determine structure novel TQ−Ox substance, we employed...
Strong evidence supports the anticancer properties of natural plant product isolates. The cytotoxic, genotoxic, and apoptotic an oxime derivative thymoquinone (TQ) in melanoma cancer cells were investigated. structure TQ-Oxime was elucidated through nuclear magnetic resonance, its effect on B16F10 L929 cell lines assessed using a luminometric adenosine triphosphate assay. Intracellular reactive oxygen species (iROS) quantified
Objectives: This study aimed to examine the effect of varying ozone doses on proinflammatory cytokine levels in synovial fluid collected from individuals with knee osteoarthritis. Patients and methods: The controlled clinical trial was conducted 82 patients (61 females, 21 males; mean age: 63.1±10.0 years; range, 40 73 years) between April 2023 20 May 2023. Synovial samples were under ultrasound guidance divided into three tubes, one which not injected ozone, other two 10 30 gamma (γ)...
Abstract Multiple sclerosis (MS) is a demyelinating nervous system disease known for its lesions and manifests itself with attacks. According to some theories, inflammation oxidative stress play an important role in MS. With this study, we aimed examine the levels of stress, DNA damage MS patients get idea about course from these data. The research comprised diagnosed between ages 18 60. Photometric techniques were used determine serum native thiol (NT), total (TT), antioxidant status (TAS),...
Effect of probiotics and melatonin on inflammatory cytokines oxidative stress status in distant organs after local radiotherapy: An experimental study