Tansel Sapmaz

ORCID: 0000-0002-7820-5837
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About
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Research Areas
  • Reproductive Biology and Fertility
  • Reproductive System and Pregnancy
  • Ovarian function and disorders
  • Effects of Radiation Exposure
  • Endometriosis Research and Treatment
  • Uterine Myomas and Treatments
  • Circadian rhythm and melatonin
  • Radiation Therapy and Dosimetry
  • Pregnancy and preeclampsia studies
  • Selenium in Biological Systems
  • Advanced Radiotherapy Techniques
  • Inflammatory mediators and NSAID effects
  • Pelvic floor disorders treatments
  • Cardiac Ischemia and Reperfusion
  • Endometrial and Cervical Cancer Treatments
  • Anesthesia and Neurotoxicity Research
  • Biochemical effects in animals
  • Protein Hydrolysis and Bioactive Peptides
  • Anorectal Disease Treatments and Outcomes
  • RNA Interference and Gene Delivery
  • Gynecological conditions and treatments
  • Antimicrobial Peptides and Activities
  • Dietary Effects on Health
  • Renal function and acid-base balance
  • Carcinogens and Genotoxicity Assessment

Istanbul University
2018-2024

Sağlık Bilimleri Üniversitesi
2019-2024

Üsküdar University
2022-2024

University of Health Sciences Antigua
2022-2024

University of Sharjah
2021

Türk Anesteziyoloji ve Reanimasyon Derneği
2019

Dr Lütfi Kırdar Kartal Eğitim ve Araştırma Hastanesi
2019

Institute of Medical Sciences
2018

Fırat University
2018

This research aims to investigate the adverse effects of ZnO NP on ovarian tissue and follicular menstrual cycle protective l-arginine aforementioned tissues.30 rats were divided into five groups. The first group was control group. second fourth groups received 100 mg/kg 200 NP, respectively. third fifth same doses as groups, However, an additional dose 1.3 gr/kg LA amino acid. are given intraperitoneal for 21 days. Blood samples from each rat a part ovarium collected test gene expression...

10.1016/j.amsu.2022.103290 article EN Annals of Medicine and Surgery 2022-01-30

It was aimed to investigate the biochemical and histopathological effects of resveratrol melatonin, via histone H4 β-defensin 1, in diabetic rats.

10.5152/tjg.2024.23068 article EN The Turkish Journal of Gastroenterology 2024-03-04

We investigated the radioprotective effect of melatonin (MEL) against thyroid gland damage in rats caused by flattening filter (FF) and free (FFF) single dose X-ray beams. used 48 female divided into six groups eight: group 1, untreated control group; 2, MEL treated 3, FF-low rate radiotherapy (FF-LDR) 4, FF-LDR + 5, FFF-high (FFF-HDR) 6, FFF-HDR group. Groups 4 6 were injected intraperitoneally (i.p.) with 10 mg/kg 15 min before exposure to radiation. The head neck regions each rat 3 5...

10.1080/10520295.2023.2189752 article EN Biotechnic & Histochemistry 2023-04-19

The purpose of the present study is to investigate protective effect melatonin against early period parotid gland damage, caused by low- and high-dose rate beams in different dose plans, using experimental rat models. Eighty Sprague Dawley rats were divided into ten randomized groups, each group being terms plan rate. Subjects control given only sodium chloride. melatonin-only received 10 mg/kg melatonin. head neck region radiotherapy plus was irradiated with single (SD) fractional (FD)...

10.1080/10420150.2021.1898392 article EN Radiation effects and defects in solids 2021-03-23

Recent studies have shown that oxidative stress, inflammation, and apoptosis play substantial roles in the pathogenesis of tissue damage distant organ during ovarian transplantation. Because their potential antioxidant anti-inflammatory properties, investigating natural compounds like curcumin gallic acid is crucial. This study investigated effects curcumin, acid, combination on liver kidney tissues a rat model

10.6002/ect.2023.0327 article EN Experimental and Clinical Transplantation 2024-09-01

Objectives: Apigenin and parthenolide as natural products have potent antioxidant anti-inflammatory outcomes that could make them a perfect option for endometriosis therapy. This study aimed to determine the effects of apigenin on created endometrial implants in rat model endometriosis. Methods: Thirty-nine mature, female Sprague-Dawley rats were assigned randomly six experimental groups four weeks after induction. Group 1 (n = 5): Control (CTRL) opened closed abdomen; 2 6): Peritoneal...

10.18621/eurj.1209679 article EN The European Research Journal 2023-01-24

Background. There is no study of whether the dysplastic changes in ovarian surface epithelium X-ray-exposed rats during hysterosalpingography (HSG) decrease or not with use Lipiodol and melatonin given both intraperitoneally (i.p.) into suspensorium ovarii.Objectives. We investigated restorative effects administration HSG procedure on rats.Material Methods. A total 50 Wistar regular estrous cycles were randomly divided 5 groups. Group 1 was control group. In other groups, X-ray applied...

10.17219/acem/70810 article EN cc-by-nc-nd Advances in Clinical and Experimental Medicine 2018-07-31

Aim: We aimed to investigate how bilateral renal ischemia-reperfusion (I/R) damage affects the ovaries as a distant organ and effects of melatonin (MEL), curcumin (CUR) melatonin+curcumin (MEL+CUR) treatments on I/R damage. Material Method: 42 female Wistar rats were used in study. Rats divided into 6 groups study was designed follows: Control group (G1) – opening closing abdomen only (sham surgery group) –, (G2) 45 min ischemia followed by 2 h reperfusion I/R+MEL (G3) ischemia,...

10.46648/gnj.276 article EN Gevher Nesibe Journal IESDR 2021-11-25

Background: To compare the changes caused by low and high dose rate radiotherapy in bladder tissue of rats to examine effect melatonin on tissue.Materials Methods: 40 adult were randomly divided into five groups with 8 each group.Radiotherapy treatment not applied group 1 (G1) control rats.A single Gy 400 MU/min was G2 G3 1400 G4 G5 rats.G3 (treated groups) given 50 mg/kg intraperitoneally 15 minutes before application.Rats sacrificed under anesthesia tissues removed.Histopathological...

10.4274/hamidiyemedj.galenos.2022.85856 article EN Hamidiye Medical Journal 2023-02-16

Objective: To examine the effects of lipiodol, melatonin, and radiation used during hysterosalpingography (HSG) on rat ovarian follicle reserve. Materials Methods: A total 50 Wistar rats with regular estrous cycles were randomly divided into five groups. Group 1 was control group. The other groups, X-ray applied (G2), 0.1 ml lipiodol to each uterine horn (G3), 20 mg/kg intraperitoneal melatonin application followed by administration after 15 minutes (G4), administered ligamentum suspensorium...

10.12891/ceog4236.2018 article EN Clinical and Experimental Obstetrics & Gynecology 2018-08-10

Background:The aim of this study to investigate whether tacker and suture materials used for mesh fixation in the laparoscopic pectopexy would yield significant differences concerning feasibility, safety, postoperative outcomes.Methods: A total 26 women who underwent between January 2015 June 2017 at Kocaeli Derince Education Research Hospital were retrospectively analyzed.Fourteen patients had onto iliopectineal ligaments, vaginal stump with polypropylene using intra-corporeal suturing...

10.5455/ijmrcr.polypropylene-suture-laparoscopic-pectopexy article EN International Journal of Medical Reviews and Case Reports 2019-01-01

Background: To investigate the effects of tannic acid (TA) use on ovarian folliculogenesis, p53 expression, and serum luteinizing hormone (LH), follicle-stimulating (FSH), testosterone (T) levels in rats with polycystic ovary syndrome (PCOS) model. Materials Methods:A total 18 Wistar female were used divided into 3 experimental groups.Group 1 (G1, control), group 2 (G2, PCOS), (G3, PCOS+TA).Rats induced letrozole for 21 days to form a PCOS model.After days, TA (40 mg/kg) was given by gavage...

10.4274/hamidiyemedj.galenos.2022.07078 article EN Hamidiye Medical Journal 2022-08-04

Abstract Purpose: The aim of this study was to investigate the effects vitamin E (Vit E) and C C) on oxidant-antioxidant system markers, ovarian follicle reserves, surface epithelium in autologous intraperitoneal transplantation rats. Materials Methods: 20 adult female Wistar Albino were randomly divided into four groups. Group 1 (n = 5), control group, only had their abdomens opened closed. 2 5): underwent an transplantation. 3 5) received mg/kg (IP) Vit 15 minutes before 4 50 IP that...

10.21203/rs.3.rs-1088363/v1 preprint EN cc-by Research Square (Research Square) 2021-11-23
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