Carolina B. Lobato

ORCID: 0000-0003-3708-6859
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About
Contact & Profiles
Research Areas
  • Bariatric Surgery and Outcomes
  • Diabetes Treatment and Management
  • Diet and metabolism studies
  • Intestinal Malrotation and Obstruction Disorders
  • Diabetes Management and Research
  • Regulation of Appetite and Obesity
  • Cardiovascular Function and Risk Factors
  • Grief, Bereavement, and Mental Health
  • Metabolism, Diabetes, and Cancer
  • Pharmacology and Obesity Treatment
  • Patient Dignity and Privacy
  • Gastrointestinal disorders and treatments
  • Diabetes and associated disorders
  • Human Health and Disease
  • Radiomics and Machine Learning in Medical Imaging
  • Body Contouring and Surgery
  • Obesity and Health Practices
  • Growth Hormone and Insulin-like Growth Factors
  • Hypothalamic control of reproductive hormones
  • Colorectal Cancer Screening and Detection
  • Palliative Care and End-of-Life Issues
  • Parathyroid Disorders and Treatments
  • Pancreatic function and diabetes
  • Biliary and Gastrointestinal Fistulas
  • Colorectal Cancer Surgical Treatments

Hvidovre Hospital
2022-2024

Copenhagen University Hospital
2024

University of Copenhagen
2022-2024

Centro de Cirugía de Mínima Invasión Jesús Usón
2024

Universidade do Porto
2018-2023

Novo Nordisk Foundation
2023

Centro Hospitalar do Porto
2021

Hospital Garcia de Orta
1998

Post-bariatric hypoglycaemia (PBH) is typically a post-prandial occurring about 2–4 h after eating in individuals who have undergone bariatric surgery. PBH develops relatively late surgery and often discharge from post-surgical follow-up by teams, leading to variability diagnosis management non-specialist centres. Aim The overall aim was improve standardise clinical practice the of PBH. objectives were: (1) undertake an up-to-date review current literature; (2) formulate practical...

10.1530/ec-23-0285 article EN cc-by-nc-nd Endocrine Connections 2024-03-07

Obesity and obesity-related diseases are major public health concerns that have been exponentially growing in the last decades. Bariatric surgery is an effective long-term treatment to achieve weight loss obesity comorbidity remission. Post-bariatric hypoglycemia (PBH) a late complication of bariatric most commonly reported after Roux-en-Y gastric bypass (RYGB). PBH end result postprandial hyperinsulinemia but additional endocrine mechanisms involved still under debate. Our aim was...

10.3389/fendo.2020.608248 article EN cc-by Frontiers in Endocrinology 2020-11-30

Abstract Introduction Post‐bariatric hypoglycaemia (PBH) is a rare yet disabling clinical condition, mostly reported after Roux‐en‐Y gastric bypass (RYGB) surgery. RYGB one of the most widely used and effective bariatric procedures. The pathophysiology PBH remains unclear, treatment options are limited in effectiveness and/or carry significant side effects. Acarbose slows carbohydrates digestion absorption generally considered first‐line pharmacological for but its gastrointestinal effects...

10.1111/dme.15320 article EN cc-by-nc Diabetic Medicine 2024-03-29

Our aim was to assess the potential of flash glucose monitoring (FGM) for diagnostic workup suspected post-bariatric hypoglycaemia (PBH). Patients (N = 13) with PBH underwent a food and symptoms diary (FSD) record along FGM over 14 days. Targeted data analysis confirmed occurrence low events in parallel meal-triggered symptoms. Glycaemic variability, as assessed by Mean Absolute Glucose change (MAG change), increased, while higher risk glycaemic excursions towards both hyper (ADRRFGMGT)...

10.1038/s41598-020-68029-8 article EN cc-by Scientific Reports 2020-07-06

Given the common anatomical features and similar short-term weight loss outcomes, Biliopancreatic Diversion with Duodenal Switch (BPD/DS) Single-Anastomosis Duodenoileal bypass Sleeve gastrectomy (SADI-S) are considered identical bariatric procedures, apart from technical complexity being lower for SADI-S. In absence of prospective randomized trials or long-term comparative studies rationale choosing between procedures is hampered. Post-bariatric hormonal profiles could contribute to...

10.1016/j.orcp.2023.02.004 article EN cc-by-nc-nd Obesity Research & Clinical Practice 2023-02-14

Iodine deficiency remains a worldwide problem with two billion individuals having insufficient iodine intake. Universal salt iodisation was declared by UNICEF and WHO as safe, cost-effective, sustainable way to tackle deficiency. In Portugal, the few studies available unravel an status below guidelines for pregnant women school-aged children. present study, levels of household consumed in Portugal assessed, first time. Non-iodised (median 14 ppm) fortified 48 marine samples showed lower than...

10.1080/09637486.2018.1498066 article EN International Journal of Food Sciences and Nutrition 2018-08-30

Identifying the prevalence of palliative care (PC) needs among patients who die at emergency department (ED) and to assess symptom control aggressiveness care.We conducted a decedent cohort study adults deceased ED Portuguese teaching hospital in 2016. PC were identified using National Hospice Organization terminality criteria comorbidities measurement by Charlson's Index.384 died (median age 82 (IQR 72-89) years) 78.4% (95% CI 73.9% 82.2%) presented needs. Only 3.0% (n=9) referred team....

10.1136/bmjspcare-2021-003332 article EN BMJ Supportive & Palliative Care 2021-09-01

Introduction & Objective: GLP-1 optimizes glycemic control mostly by stimulating insulin and suppressing glucagon secretion. During hypoglycemia, the activity is abolished through unclear pathways. The parasympathetic nervous system, via vagus nerve, modulates pancreatic hormone secretion during hypoglycemia. nerve fibers run along esophagus stomach walls, innervate pancreas distally. We investigated role of anatomical integrity in modulating endocrine response to cholinergic under...

10.2337/db24-1620-p article EN Diabetes 2024-06-14

Abstract Introduction This study outlines the design and implementation of an application focused on optimizing surgical planning for colon surgery through automated segmentation process Computed Axial Tomography (CT) images. The tool provides continuous assistance to user, enhancing overall management efficiency. Methods A module has been developed 3DSlicer image computing platform. algorithm was programmed in Python, primarily utilizing Slicer, MRML, VTK libraries. Additionally, DICOM...

10.1093/bjs/znae018.020 article EN British journal of surgery 2024-02-01

Approaching the patient presenting symptoms compatible with post-bariatric hypoglycaemia (PBH) is a major clinical challenge for surgeons, endocrinologists, nutritionists, and primary care physicians. Raising hypothesis of PBH as differential diagnosis requires high degree suspicion, since features at presentation are highly unspecific overlap those dumping syndrome, which prevalent in this population. The temporal relationship between food intake poses an additional laboratorial...

10.34635/rpc.884 article EN Revista Portuguesa de Cirurgia 2021-08-09
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