A5091198986- Cardiac Imaging and Diagnostics
- Acute Myocardial Infarction Research
- Cardiovascular Function and Risk Factors
- Coronary Interventions and Diagnostics
- Heart Failure Treatment and Management
- Erythropoietin and Anemia Treatment
- Frailty in Older Adults
- COVID-19 and healthcare impacts
- Iron Metabolism and Disorders
- Cardiovascular and exercise physiology
- Cardiovascular Issues in Pregnancy
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Health and Mental Health
- Hip and Femur Fractures
- Hydrogen embrittlement and corrosion behaviors in metals
- Hemoglobinopathies and Related Disorders
- Cardiac Valve Diseases and Treatments
- COVID-19 Clinical Research Studies
- Health Systems, Economic Evaluations, Quality of Life
- Pregnancy-related medical research
- Advanced MRI Techniques and Applications
- Blood Coagulation and Thrombosis Mechanisms
- Muscle activation and electromyography studies
- Effects of Vibration on Health
- Pulmonary Hypertension Research and Treatments
Hospital Quirón Torrevieja
2024
Hospital Clínico Universitario de Valencia
2016-2023
INCLIVA Health Research Institute
2020-2023
Centro de Investigación Biomédica en Red
2020-2023
Centro de Investigación en Red en Enfermedades Cardiovasculares
2018-2023
Universitat de València
2016-2021
Hospiten Group
2016
Background Intravenous ferric carboxymaltose ( FCM ) improves symptoms, functional capacity, and quality of life in heart failure iron deficiency. The mechanisms underlying these effects are not fully understood. aim this study was to examine changes myocardial content after administration patients with deficiency using cardiac magnetic resonance. Methods Results Fifty‐three stable were randomly assigned 1:1 receive intravenous or placebo a multicenter, double‐blind study. T2* T1 mapping...
A non-neglectable percentage of patients with non-ST elevation myocardial infarction (NSTEMI) show non-obstructive coronary arteries (MINOCA). Specific data in older are scarce. We aimed to identify the clinical predictors MINOCA admitted for NSTEMI and explore long-term prognosis MINOCA. This was a single-center, observational, consecutive cohort study (≥70 years) between 2010 2014 who underwent angiography. Univariate multivariate Cox regression were performed analyze association variables...
Abstract The aim of this case report is to assess the potential role intrarenal Doppler ultrasonography as a non‐invasive method evaluate venous flow (IRVF) in acute heart failure (AHF) and concomitant renal dysfunction. We an 81‐year‐old woman with valvular disease (previous mitral valve replacement) that presented acutely decompensated worsening function (WRF). In addition complete physical examination, laboratory analysis, echocardiography, IRVF was assessed at baseline 48 h after...
Aim: We evaluated the relationship between iron deficiency (ID) and long-term mortality risk in elderly patients with acute coronary syndrome (ACS). Methods: In this prospective observational study, we included 252 older than 65 years ACS. Transferrin saturation (TSAT) ferritin were collected before discharge. Results: Mean age, hemoglobin GRACE score 78 ± 7 years, 12.4 1.8 g/dl 138.8 25.3, respectively, 112(44.4%) women, 151(59.9%) presented ID. During follow-up, 121 (48%) died. Mortality...
Background Cardiac magnetic resonance (CMR) permits robust risk stratification of discharged ST-segment-elevation myocardial infarction patients, but its indiscriminate use in all cases is not feasible. We evaluated the utility left ventricular ejection fraction (LVEF) by echocardiography for a selective CMR after infarction. Methods Echocardiography and were performed 1119 patients included multicenter registry. The prognostic power beyond echocardiography-LVEF was assessed using adjusted C...
Background The mechanisms explaining the clinical benefits of ferric carboximaltose (FCM) in patients with heart failure, reduced or intermediate left ventricular ejection fraction, and iron deficiency remain not fully clarified. Myocardial-IRON trial showed short-term cardiac magnetic resonance (CMR) changes suggesting myocardial repletion following administration FCM but failed to find a significant increase fraction whole sample. Conversely, strain assessment could evaluate more...
Treatment with intravenous ferric carboxymaltose (FCM) has been shown to improve symptoms, functional capacity, and quality of life in patients heart failure iron deficiency. However, the underlying mechanisms for these beneficial effects remain undetermined. The aim this study is quantify cardiac magnetic resonance changes myocardial content after administration FCM deficiency contrast them parameters severity. This a multicenter, double‐blind, randomized study. Fifty stable symptomatic...
Background Undetectable high-sensitivity cardiac troponin (hs-cTn) in a single determination upon admission may rule out acute coronary syndrome. We investigated undetectable hs-cTnT (<detection limit; <5 ng/l) together with clinical risk scores (GRACE, TIMI, HEART and previously published simple score), for one-year outcomes patients chest pain normal (<99th percentile; <14 admission. Methods This study was retrospective design involving 2254 consecutive (July...
We aimed to compare the prognostic value of two different measures, Fried’s Frailty Scale (FFS) and Clinical (CFS), following myocardial infarction (MI). included 150 patients ≥ 70 years admitted from AMI. was evaluated on day before discharge. The primary endpoint number days alive out hospital (DAOH) during first 800 days. Secondary endpoints were mortality a composite reinfarction. diagnosed in 58% 34% using FFS CFS scales, respectively. During 34 deaths 137 admissions occurred. DAOH...
Differences exist in the diagnosis and treatment of acute coronary syndrome (ACS) between men women. However, recent advancements management ACSs might have attenuated this sex gap. We evaluated status ACS a multicenter registry 10 tertiary Spanish hospitals.We enrolled 1056 patients our study, including only those with type 1 myocardial infarctions or unstable angina presumably not related to secondary cause an 'all-comers' design.The women (29%) were older than (71.0 ± 12.8 vs. 64.0 12.3,...
Abstract Heart failure with preserved ejection fraction ( HFpEF ) has become the most prevalent form of heart in developed countries. Regrettably, there is no evidence‐based effective therapy for . We seek to evaluate whether inspiratory muscle training, functional electrical stimulation, or a combination both can improve exercise capacity as well left ventricular diastolic function, biomarker profile, quality life QoL ), and prognosis patients A total 60 stable symptomatic (New York...
To evaluate the 5 components of Fried frailty phenotype (self-reported unintentional weight loss, physical activity questionnaire, gait speed, grip strength, and self-reported exhaustion) for long-term outcomes in elderly survivors acute coronary syndrome.A total 342 consecutive patients (from October 1, 2010, to February 2012) were included. The score albumin concentration, as malnutrition index, assessed before hospital discharge. Patients followed up until April 2020 (median follow-up,...
Frailty is a marker of poor prognosis in older adults after acute coronary syndrome. We investigated whether cognitive impairment provides additional prognostic information. The study population consisted prospective cohort 342 (>65 years) adult survivors (Fried score) and function (Pfeiffer’s Short Portable Mental Status Questionnaire—SPMSQ) were assessed at discharge. endpoints mortality or myocardial infarction 8.7-year median follow-up. Patient distribution according to SPMSQ results...
Decision-making is challenging in patients with chest pain and normal high-sensitivity cardiac troponin T (hs-cTnT; <99th percentile; <14 ng/L) at hospital arrival. Most of these might be discharged early. We investigated clinical data hs-cTnT concentrations for risk stratification. This a retrospective study including 4476 consecutive presenting to the emergency department first hs-cTnT. The primary endpoint was one-year death or acute myocardial infarction, secondary added urgent...