A5048077437- Viral gastroenteritis research and epidemiology
- Mesenchymal stem cell research
- Health Systems, Economic Evaluations, Quality of Life
- Healthcare Policy and Management
- Primary Care and Health Outcomes
- Pneumonia and Respiratory Infections
- Influenza Virus Research Studies
- Vaccine Coverage and Hesitancy
- Hematopoietic Stem Cell Transplantation
- Virus-based gene therapy research
- Bacterial Infections and Vaccines
- Orthopaedic implants and arthroplasty
- Lipid Membrane Structure and Behavior
- Biomedical and Engineering Education
- Signaling Pathways in Disease
- 3D Printing in Biomedical Research
- Neuropeptides and Animal Physiology
- Bone Metabolism and Diseases
- Hepatitis Viruses Studies and Epidemiology
- Respiratory viral infections research
- Animal Virus Infections Studies
- Periodontal Regeneration and Treatments
- Global Health Care Issues
- Global Maternal and Child Health
- Fibroblast Growth Factor Research
Karus Therapeutics (United Kingdom)
2020
GlaxoSmithKline (Belgium)
2016-2017
UCLouvain
2003-2004
Orthopaedic Research
2001
Inserm
1999-2000
Hôpital Lariboisière
2000
The benefits of rotavirus (RV) vaccination in developed countries have focused on reductions mortality, hospitalization and medical visits, herd protection. We investigated other aspects related to RV-induced nosocomial infection, duration hospital stay, age shift, sustained vaccine impact (VI) over time. RotaBIS (Rotavirus Belgian Impact Study; ClinicalTrials.gov identifier, NCT01563146) annually collects retrospective data linked RV testing children up 5 years old from 11 pediatric wards...
During each winter the hospital quality of care (QoC) in pediatric wards decreases due to a surge infectious diseases leading overcrowded units. Bed occupancy rates often surpass good bed management threshold 85%, which can result poor conditions workplace. This study explores how QoC-scores could be improved by investing additional beds and/or better vaccination programs against vaccine-preventable diseases.The Cobb-Douglas model was selected define improvement QoC (%) as function two...
Many countries struggle with the prioritisation of introducing new vaccines because budget limitations and lack focus on public health goals. A model has been developed that defines how specific goals can be optimised through immunisation within vaccination constraints. Japan, as a country example, could introduce 4 pediatric targeting influenza, rotavirus, pneumococcal disease mumps known burden disease, vaccine efficacies maximum achievable coverages. Operating under constraints,...
Abstract Objectives Countries have constrained healthcare budgets and must prioritize new interventions depending on health goals time frame. This situation is relevant in the sphere of national immunization programs, for which many different vaccines are proposed, limited, efficient choices be made order vaccine introduction. Methods A optimization (CO) model infectious diseases was developed intervention types (prophylaxis treatment) were combined consideration Malaysia. Local experts...
In order to minimize the risk of contamination associated with tissue transplantation, banks commonly chemically treat tissues whenever possible. As viral inactivation uses agents lethal microorganisms, it is imperative assure that inactivated remains biocompatible. vitro assays can be an effective means assess acute cytotoxicity treated human allografts. We have used different types cells cultured in presence extract. A standard cell line, a fibroblast (WI38), which was same for all...
Before 2006 bed occupancy rates during winter periods were above the good management threshold (85%) in Jessa Hospital paediatric ward (Hasselt, Belgium), with peaks 100%. This causes pressure on and people expressed bad QoC scores. We evaluated two methods to improve scores their investment costs. Option A is extending number of beds until unit operates under 85% whole season. B introducing rotavirus vaccination infants high coverage catchment area. hospital 36 was selected as pilot design....
Abstract In this study we characterized the biological activity of recently identified salmon calcitonin (sCT) IV, in order to evaluate its potential therapeutic value. rat bioassay, sCT IV exhibited a 30% higher hypocalcemic than I. The capacity molecule inhibit bone resorption was assessed vitro by resorbing assay and pit assay. An inhibitory effect, similar that I, observed both assays. interaction with rabbit CT receptor also studied. affinity for as potency stimulating cAMP production....
Health authorities may face a variety of options when deciding upon expanding their national pediatric immunization programs, ranging between an ad-hoc vaccine selection versus targeted multi-year program to achieve efficiency goals. The portfolio management model allows the comparison these two over fixed period time. This optimization is based on disease burden, impact and associated costs which are balanced against available vaccination budget pre-defined public health priorities....