- HIV/AIDS Research and Interventions
- HIV/AIDS drug development and treatment
- HIV Research and Treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Tuberculosis Research and Epidemiology
- HIV-related health complications and treatments
- Adolescent Sexual and Reproductive Health
- Cervical Cancer and HPV Research
- Trypanosoma species research and implications
- Fungal Infections and Studies
- Neurological and metabolic disorders
- Hepatitis B Virus Studies
- Research on Leishmaniasis Studies
- Cancer Risks and Factors
- Science and Education Research
- Orthopedic Surgery and Rehabilitation
- Peripheral Nerve Disorders
- Antifungal resistance and susceptibility
- Mycobacterium research and diagnosis
- Hemoglobinopathies and Related Disorders
- Breast Cancer Treatment Studies
- Toxin Mechanisms and Immunotoxins
- Brucella: diagnosis, epidemiology, treatment
- Gallbladder and Bile Duct Disorders
- Motor Control and Adaptation
Universidade Federal de São Paulo
2005-2024
Fundação de Apoio à Universidade Federal de São Paulo
1998-2012
Associação Paulista de Medicina
1986-2003
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Este estudo tem por objetivo traduzir, fazer a equivalência cultural e validar o questionário de Levine et al. (1993) ou Boston Carpal Tunnel Questionnaire (BCTQ), para português. O BCTQ aplicado pacientes selecionados pela pergunta "Qual motivo que a(o) levou procurar médico fez com ele solicitasse este exame?" mostrou boa reprodutibilidade. A validade foi medida comparando escore gravidade dos sintomas (EGS) do estado funcional (EEF) aos resultados testes força preensão pinça, Minnesota,...
No AccessJournal of Urology1 Apr 1992Risk Factors for Nosocomial Urinary Tract and Postoperative Wound Infections in Renal Transplant Patients: A Matched-Pair Case-Control Study Milton S. Lapchik, Adauto Castelo Filho, José Osmar A. Pestana, Álvaro P. Silva Sérgio B. Wey LapchikMilton Lapchik More articles by this author , FilhoAdauto Filho PestanaJosé Pestana FilhoÁlvaro WeySérgio View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)37444-XAboutPDF ToolsAdd to favoritesDownload...
Transcranial Doppler (TCD) is the key test in determining need for prophylactic blood transfusion to prevent stroke children with sickle cell disease (SCD). The role of TCD assessing risk adults SCD as well pattern velocities these patients are still undetermined.The authors compared (n=56) those healthy controls (n=56).Velocities were lower than found and higher negatively correlated hematocrit both groups.The different from that described children. Age-specific criteria may assist...
We report a fast (less than 3 h) and cost-effective melting temperature assay method for the detection of single-nucleotide polymorphisms in MBL2 gene. The protocol, which is based on Corbett Rotor Gene real time PCR platform SYBR Green I chemistry, yielded, cohorts studied, sensitive (100%) specific amplification without use costly fluorophore-labeled probes or post-PCR manipulation. At end PCR, dissociation protocol included slow heating from 60º to 95ºC 0.2ºC steps, with an 8-s interval...
Brazil was the first country to provide unrestricted, cost-free access antiretroviral (ARV) medicine for AIDS treatment. However, there is little data about benefits of such a policy these patients. We evaluated duration benefit obtained with introduction ARVs, defined as durability ARV regiment. reviewed medical charts patients attended from 1996-2000, at outpatient clinics Federal University São Paulo, Brazil. A total 120 drug-naive HIV-1 infected were eligible participate in study. About...
breast cancer is the with highest incidence in women Brazil, representing 29.7% of all cancers. More than two thirds show expression for hormone receptors, and these cases, therapy tamoxifen indicated, which may represent a risk factor development endometrial (four-fold greater relative risk).
Evaluation of TNF-alpha in patients with Kala-azar has drawn increasing interest due to its regulatory role on the immune system, addition cachetizing activity. The objective this study was examine association between plasma levels TNF-alpha, measured by immunore-activity (ELISA) and bioactivity (cytotoxicity assay L-929 cells), clinical manifestations visceral leishmaniasis. Plasma samples from 19 were obtained before, during at end antimonial therapy. determinations done using cytotoxicity...
In the present study, we investigated influence of HIV-1 subtype in response to dendritic cell (DC) therapeutic vaccine for HIV. viral load and TCD8+/TCD4+ counts up 48 weeks after vaccination. Out 19 immunized subjects, 13 were infected by B, 5 F, 1 D. Overall, 42.1% (8/19) achieved a decline ≥ log(10) sustained immunization. Such magnitude drop was seen 80% (4/5) F patients, 23.0% (3/13) B ones (p=0.08). Moreover, mean 1.32 log(10), individuals compared 0.5 among patients (p=0.01). The...
OBJETIVO: Avaliar a qualidade de vida (QV) gestantes infectadas pelo HIV, utilizando o questionário HIV/AIDS - Targeted Quality of Life (HAT-QoL). MÉTODOS: Estudo descritivo que incluiu 60 atendidas no Núcleo Multidisciplinar Patologias Infecciosas na Gestação (NUPAIG) UNIFESP/EPM e rede referência da Secretaria Municipal São Paulo. Foi realizado período fevereiro 2011 outubro 2012. Foram coletadas variáveis sociodemográficas clínicas responderam HAT-QoL, qual 34 questões sobre vida....
Transmission of American trypanossomiasis by transfusion has been reduced expansion control measures blood quality in Brazil. A research project was, therefore, undertaken to evaluate soropositivity for Trypanosoma cruzi infection on donors and compare this rate with those found 1958 1975 banks.A transversal study was carried out Londrina, Paraná, ELISA Immunofluorescence were the serological test techniques used diagnosis infection.A serumprevalence 1.3% a tendency positive serum findings...
Antígeno del polisacárido capsular (Ag PC) de Cryptococcus neoformans fue detectado por la técnica aglutinación latex (AL) en LCR y suero pacientes con Sindrome Inmunodeficiencia Adquirida (SIDA) primer episodio neurocriptococosis, usando como patrón el examen micológico (examen directo cultivo) LCR. Se obtuvo una sensibilidad 100% AL para detectar AgPC C. neoformans, cual su rápidez permite tratamiento específico precoz. Títulos iniciales levadura esos pueden ser > 1.000.000, pareciendo...
Com o objetivo de conhecermos os motivos encaminhamento para estudo eletrofisiológico, perguntamos a 490 pacientes, encaminhados dois laboratórios neurofisiologia (UNIFESP e UNEF): "Qual motivo que a(o) levou procurar médico fez com ele solicitasse este exame"? Parestesia e/ou dor nas mãos punhos foram espontaneamente referidas como principal por 175 deles (26% UNIFESP 40% UNEF). O exame eletroneuromiográfico foi normal em, respectivamente, 30,8% 35,3% revelou compressão do nervo mediano no...
HIV RNA plasma viral load (VL) is the standard surrogate marker to monitor response antiretroviral treatment (ART). We compared linearity, repeatability, and concordance of six commercially available VL platforms using clinical samples from patients Brazilian sites where different HIV-1 subtypes co-circulate. A total 150 each city were collected in Curitiba, Southern Brazil (subtype C), São Paulo B), Santos (BF recombinants), Southeast Brazil. Platforms VERSANT® Siemens 1.0 (kPCR); 3.0...
RESUMO Introdução: o câncer da mama é de maior incidência no sexo feminino Brasil, representando 29,7% todos os cânceres. Mais dois terços das mulheres com apresentam expressão para receptores hormonais, estando, nestes casos, indicada a terapia hormonal tamoxifeno, que pode representar fator risco desenvolvimento do endométrio (risco relativo quatro vezes maior). Objetivo: este trabalho teve como objetivo avaliar associação entre uso tamoxifeno e distúrbios endometriais bem eventuais outros...
Mycobacterium avium complex (MAC) is frequently isolated from patients with late complications of Acquired Immunodeficiency Syndrome (AIDS), especially in North America and Europe. However, its isolation the central nervous system (CNS) has been seldom reported these countries. MAC infections AIDS African Latin American countries are believed to be uncommon. We report cerebrospinal fluid (CSF) 11 out 1723 (0.63%) seen at "Centro de Referência e Treinamento - AIDS", São Paulo discuss...
Com o objetivo de racionalizar emprego recursos econômicos em programas vacinação contra hepatite B, profissionais da área saúde, foram estudados dois aspectos distintos: necessidade ou não triagem sorológica pré-vacinação e viabilidade utilização doses reduzidas vacina por via intradérmica (ID). A análise econômica custo-minimização demonstrou que com prevalência imunes na população a ser vacinada superior 11% (o ocorreu nosso estudo apenas no grupo funcionários) passou economicamente...