A5037715168- Anatomy and Medical Technology
- Innovations in Medical Education
- Surgical Simulation and Training
- Organ Donation and Transplantation
- Alzheimer's disease research and treatments
- Ethics and Legal Issues in Pediatric Healthcare
- Transplantation: Methods and Outcomes
- Palliative Care and End-of-Life Issues
- Organ Transplantation Techniques and Outcomes
- Biomedical and Engineering Education
- Diversity and Career in Medicine
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Intracranial Aneurysms: Treatment and Complications
- Neuroinflammation and Neurodegeneration Mechanisms
- Adolescent and Pediatric Healthcare
- Traumatic Brain Injury and Neurovascular Disturbances
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Neurosurgical Procedures and Complications
- Computational Drug Discovery Methods
- Advanced Fluorescence Microscopy Techniques
- S100 Proteins and Annexins
- Muscle and Compartmental Disorders
- 14-3-3 protein interactions
- Family and Patient Care in Intensive Care Units
- Simulation-Based Education in Healthcare
John Radcliffe Hospital
2022-2023
University of Oxford
2022-2023
University of Southampton
2017-2022
Oxford University Hospitals NHS Trust
2021
Buckinghamshire Healthcare NHS Trust
2020
Stoke Mandeville Hospital
2020
Southampton General Hospital
2018
Ethics and Public Policy Center
2018
Harvard University
2002-2017
Boston Children's Hospital
2007-2017
Abstract We performed a 15-year post-mortem neuropathological follow-up of patients in the first trial amyloid-β immunotherapy for Alzheimer’s disease. Twenty-two participants clinical active amyloid-β42 immunization (AN1792, Elan Pharmaceuticals) or placebo were studied. Comprehensive assessments from 4 months to 15 years after trial. analysed relationships between topographical distribution removal cerebral cortex and tau pathology, cerebrovascular territories, plasma anti-AN1792 antibody...
Background Near-peer teaching is used in anatomy education because of its benefits to the learner, teacher and faculty members. Despite range reports focusing on advantages for teacher, which are thought include communication skills, subject knowledge employability, only beginning be explored. Method A questionnaire was distributed teachers involved near-peer at University Southampton Brighton Sussex Medical School (BSMS). This designed using a rating scale 0–10 assess perspectives their...
The US Food and Drug Administration’s December 2016 approval of nusinersen for the treatment patients with all subtypes spinal muscular atrophy ushered in a new era atrophy, their families, those involved care. extreme cost medication complicated logistical requirements administering via lumbar puncture have created practical challenges that raise important ethical considerations. We discuss 6 faced at institutional level United States: cost, limited evidence, informed consent, allocation,...
Anatomy education research has identified neuroanatomy and pelvic anatomy as particularly challenging to medical students. However, perceptions of the whole undergraduate curriculum have not been properly determined. One hundred eighty-five second year student evaluations showed that head neck were rated significantly harder than remainder (p < 0.0001). students at National Undergraduate Neuroanatomy Competition did rate other subjects. This study identifies topics which are perceived be...
The aims of this project were to describe whether pediatric clinical staff members believe that a donation after cardiac death (DCD) program could be consistent with the mission and core values children's hospital identify what consider essential acceptability such program.Qualitative study.Children's hospital.Pediatric staff.Data gathered from during eight focus groups conducted in March April 2005.Eighty-eight participated. Six major themes emerged qualitative analysis data: a) identifying...
Within medical education a reduction in curriculum time for subjects, such as anatomy puts pressure on educators to ensure the same learning outcomes are conveyed less time. This has potential impact negatively student experience. Near-peer teaching (NPT) is often praised an effective revision tool, but its use frontline resource remains unreported. The study explores NPT promote delivery of and maximize experience within neuroanatomy module second year students. occurred three educational...
We present the case of a 19-month-old boy with complex congenital heart disease. His single father is skeptical traditional medicine and does not offer social support needed to make transplantation successful for his son. After demonstrates commitment transplant success provides enhanced support, doctors place child on Berlin Heart (a biventricular assist device) as bridge list him transplant. When matched donor heart, refuses transplantation, despite that it child's only chance survival....
The National Organ Transplant Act stipulates that deceased donor organs should be justly and wisely allocated based on sound medical criteria. Allocation schemes are consistent across the country, specific policies publicly vetted. Patient selection criteria largely in hands of individual organ transplant programs, standards less evident. This has been particularly apparent for patients with developmental disabilities (DDs). In response to concerns regarding fairness evaluations DDs, we...
ObjectivesThe epidemiology of non-traumatic subarachnoid hemorrhage (SAH) is unclear. This study describes the antecedent characteristics SAH patients, compares risk between women and men, explores if this changes with age.Materials methodsRetrospective cohort using an electronic health records network based in USA (TriNetX). All patients aged 18-90y at least one healthcare visit were included. Antecedent (ICD-10 code I60) measured. The incidence proportion relative estimated overall, 55-90y...
<ns4:p>This article was migrated. The marked as recommended. Near-peer teaching (NPT) is becoming increasing popular in medical education. rationale and benefits of introducing such programs have been well documented are usually described terms their advantages to the teacher, students faculty. As a team that successfully introduced two NPT anatomy last six years at University Southampton, we taken largely evidenced based approach offering 10 considerations ensure implementation sustainable...
Parts and products of the human body are increasingly important to biomedical research. Tumors removed in surgery help researchers map molecular progression cancer. Blood samples matched clinical profiles suggest role genes other factors disease. Both hospital patients visitors World Wide Web may be approached provide tissues for study. Sometimes this research results commercial developments that produce substantial financial rewards researchers, biotechnology companies pharmaceutical or...
Undergraduates often perceive neuroscience to be a challenging discipline. As the scope of continues expand, it is important provide undergraduates with sufficient opportunities develop their knowledge and skills aim encouraging future generation basic clinical neuroscientists. Through our experience developing National Undergraduate Neuroanatomy Competition (NUNC), we have accrued an extensive volume performance data subjective insight into delivery undergraduate neuroanatomy education,...
Current tissue-clearing protocols for imaging in three dimensions (3D) are typically applied to optimally fixed, small-volume rodent brain tissue - which is not representative of the found diagnostic neuropathology laboratories. We present a method visualise cerebral cortical vasculature 3D human post-mortem had been preserved formalin many years. Tissue blocks cortex from two control cases, Alzheimer's brains and cases patients immunised against Aβ42 were stained with fluorescent...
Methods of assessment in anatomy vary across medical schools the United Kingdom (UK) and beyond; common methods include written, spotter, oral assessment. However, there is limited research evaluating these regards to student performance perception. The National Undergraduate Neuroanatomy Competition (NUNC) held annually for students throughout UK. Prior 2017, competition asked open-ended questions (OEQ) spotter examination, subsequent years also single best answer (SBA) questions. aim this...
Aims and method To investigate whether a psychiatry-specific virtual on-call training programme improved confidence of junior trainees in key areas psychiatry practice. The comprised one 90 min lecture 2 h simulated shift where participants were bleeped to complete series common tasks, delivered via Microsoft Teams. Results Thirty-eight attended the lecture, with significant improvement performing seclusion reviews ( P = 0.001), prescribing psychiatric medications for acute presentations...