A5058931656- Sarcoma Diagnosis and Treatment
- Advanced Fluorescence Microscopy Techniques
- Ovarian cancer diagnosis and treatment
- Cancer and Skin Lesions
- Cell Image Analysis Techniques
- Lymphoma Diagnosis and Treatment
- Nonmelanoma Skin Cancer Studies
- Bone Tumor Diagnosis and Treatments
- Photoacoustic and Ultrasonic Imaging
- Uterine Myomas and Treatments
- Cutaneous Melanoma Detection and Management
- Endometrial and Cervical Cancer Treatments
- Breast Cancer Treatment Studies
- Molecular Biology Techniques and Applications
- Colorectal and Anal Carcinomas
- Gastrointestinal disorders and treatments
- CAR-T cell therapy research
- Congenital Anomalies and Fetal Surgery
- Glioma Diagnosis and Treatment
- Bone health and treatments
- Ocular Oncology and Treatments
- Pancreatic and Hepatic Oncology Research
- Genetic and rare skin diseases.
- Management of metastatic bone disease
- Gastric Cancer Management and Outcomes
Carol Davila University of Medicine and Pharmacy
2014-2025
Clinical Emergency Hospital Bucharest
2016-2025
Emergency University
2018-2024
Amita Health St. Mary's Hospital
2020-2024
Bucharest Emergency University Hospital
2020-2024
Avila University
2016
Liposarcomas are some of the most challenging soft tissue tumors and subclassified into multiple subtypes with special histologic molecular features. The peculiarities each histopathological subtype influence clinical behavior, management, treatment these neoplasms. For instance, well-differentiated liposarcomas common malignancies usually display a favorable outcome. On other hand, pleomorphic liposarcoma is rarest, yet aggressive liposarcoma. This diagnosis may be due to scarce available...
Diagnosing cutaneous melanomas relies mainly on histopathological analysis, which, in selected cases, can be aided by immunohistochemical evaluation of conventional melanocytic markers. Nevertheless, these malignancies, particularly metastatic settings, may display divergent differentiation with unusual histological and features. In this context, we present the case a 65-year-old male diagnosed typical superficial spreading melanoma who developed recurrence lesions featuring angiosarcomatous...
Second Harmonic Generation Microscopy (SHG) is generally acknowledged as a powerful tool for the label-free 3D visualization of tissues and advanced materials, with one its most popular applications being collagen imaging. Although great need, progress in super-resolved SHG imaging lags behind developments reported over past years fluorescence-based optical nanoscopy. In this work, we quantitatively show on collagenous that by combining re-scan microscopy resolutions surpass diffraction...
Background and Objectives: Peripheral nerve defect regeneration is subject to ongoing research regarding the use of conduits associated with various cells or molecules. This article aims correlate histopathological clinical outcomes at end a 12-week experiment performed on rat sciatic model show which repair method has best results. Materials Methods: Forty male Wistar rats were divided into four groups compare results different methods reconstruction for defect: (1) graft–control group, (2)...
Liposarcomas are malignant soft tissue tumours with heterogeneous features and variable prognosis. Each entity comprised in this group displays distinct morphology harbours specific genetic alterations, which correlate clinical behaviour therapy response. The aim of study is to analyse the histopathological that can influence prognosis liposarcoma. We also present a newly designed scoring system could be useful for predicting risk disease progression death patients different liposarcoma...
Hair loss is a widespread issue affecting both men and women, with significant aesthetic psychological impacts. This study aimed to evaluate various hair restoration treatments, assess patient satisfaction, identify the correlations between treatment types, duration, outcomes. We conducted retrospective observational on 50 patients who completed 26-question online survey about their experience, treatments tried, satisfaction levels. The included FDA-approved drugs (finasteride minoxidil),...
Background/Objectives: Pontine cavernomas are rare and challenging vascular malformations, representing a critical subset of brainstem lesions due to their deep location proximity essential neural structures. When hemorrhagic, these can cause rapid neurological deterioration, posing life-threatening risks. Management requires delicate balance between aggressive intervention preserving vital functions. This case report presents the successful surgical treatment giant hemorrhagic pontine...
Background: Alcohol use and hypertriglyceridemia are the second third common causes of acute pancreatitis after choledocholithiasis. Still, few studies directly compare severity outcomes these two groups, which share pathophysiology pathways. Methods: In our study, we compared biologic profile, according to Atlanta classification Balthazar index, intensive care unit admissions, mortality between patients with hypertriglyceridemia-induced (HTGP) alcohol-induced (AAP). A total 78 were included...
Glioblastoma (GBM), the most aggressive primary brain tumor, poses a significant challenge in predicting patient survival due to its heterogeneity and resistance treatment. Accurate prediction is essential for optimizing treatment strategies improving clinical outcomes. This study utilized metadata from 135 GBM patients, including demographic, clinical, molecular variables such as age, Karnofsky Performance Status (KPS), MGMT promoter methylation, EGFR amplification. Six machine learning...
Histopathological image analysis performed by a trained expert is currently regarded as the gold-standard for diagnostics of many pathologies, including cancers. However, such approaches are laborious, time consuming and contain risk bias or human error. There thus clear need faster, less intrusive more accurate diagnostic solutions, requiring also minimal intervention. Multiphoton microscopy (MPM) can alleviate some drawbacks specific to traditional histopathology exploiting various...
Sarcina ventriculi is an extremely rare pathogen. These gram-positive cocci bacteria are rarely identified in gastric biopsies and usually described the scientific literature as incidental finding, particularly patients with delayed emptying, gastroparesis, emphysematous gastritis or perforation. It occurs most commonly adult women can be easily by its distinctive morphologic features, such basophilic staining, cuboidal shape, tetrad arrangement, red blood cell-sized packets, flattened cell...
Second harmonic generation (SHG) microscopy has emerged over the past two decades as a powerful tool for tissue characterization and diagnostics. Its main applications in medicine are related to mapping collagen architecture of in-vivo, ex-vivo fixed tissues based on endogenous contrast. In this work we present how H&E staining excised influences extraction use image parameters specific polarization-resolved SHG (PSHG) microscopy, which known provide quantitative information structure...