A5015204650- Muscle activation and electromyography studies
- EEG and Brain-Computer Interfaces
- Olfactory and Sensory Function Studies
- Cardiovascular Health and Disease Prevention
- Neuroscience and Neural Engineering
- Neurological disorders and treatments
- Heart Rate Variability and Autonomic Control
- Cardiovascular Function and Risk Factors
- Coronary Interventions and Diagnostics
- Motor Control and Adaptation
- Human-Animal Interaction Studies
- Mental Health Research Topics
- Pregnancy and preeclampsia studies
- Neural dynamics and brain function
- COVID-19 epidemiological studies
- Non-Invasive Vital Sign Monitoring
- Neural Networks and Applications
- HIV Research and Treatment
- Parkinson's Disease Mechanisms and Treatments
- Infection Control and Ventilation
- Sleep and related disorders
- Fungal Biology and Applications
- Fungal and yeast genetics research
- Birth, Development, and Health
- Bauxite Residue and Utilization
Alcoa (Australia)
2023
Rhodes College
2016-2018
St. Jude Children's Research Hospital
2016
Auburn University
1985-2009
Archinoetics (United States)
2009
Shirley Ryan AbilityLab
2004-2007
Northwestern University
2005
University of Cape Town
2001-2005
Sports Science Institute of South Africa
2005
University College Dublin
2003-2004
Abstract Clinical sleep evaluations currently require multimodal data collection and manual review by human experts, making them expensive unsuitable for longer term studies. Sleep staging using cardiac rhythm is an active area of research because it can be measured much more easily a wide variety both medical consumer-grade devices. In this study, we applied deep learning methods to create algorithm automated stage scoring the instantaneous heart rate (IHR) time series extracted from...
Bacterial pathogens produce complex carbohydrate capsules to protect against bactericidal immune molecules. Paradoxically, the pneumococcal capsule sensitizes bacterium antimicrobial peptides found on epithelial surfaces. Here we show that upon interaction with peptides, encapsulated pneumococci survive by removing from cell surface within minutes in a process dependent suicidal amidase autolysin LytA. In contrast classical bacterial autolysis, during shedding, LytA promotes survival and is...
Abstract Sensor-based remote monitoring could help better track Parkinson’s disease (PD) progression, and measure patients’ response to putative disease-modifying therapeutic interventions. To be useful, the remotely-collected measurements should valid, reliable, sensitive change, people with PD must engage technology. We developed a smartwatch-based active assessment that enables unsupervised measurement of motor signs PD. Participants early-stage ( N = 388, 64% men, average age 63) wore...
Background Although effective mental health treatments exist, the ability to match individuals optimal is poor, and timely assessment of response difficult. One reason for these challenges lack objective measurement psychiatric symptoms. Sensors active tasks recorded by smartphones provide a low-burden, low-cost, scalable way capture real-world data from patients that could augment clinical decision-making move field closer measurement-based care. Objective This study tests feasibility fully...
Bauxite residue is a highly saline-sodic tailings material formed as by-product of the Bayer process for alumina production. In situ remediation bauxite has potential to provide an effective means accelerated rehabilitation storage areas. However, previous work predominantly only used chemical and physical amendments date, limiting rates pH neutralisation extent remediation. Combining these abiotic with recently developed microbial biotechnology may transform into productive soil in shorter...
BACKGROUND: In investigations of the human motor system, two approaches are generally employed toward identification common modulating drives from unit recordings. One is a frequency domain method and uses coherence function to determine degree linear correlation between each component signals. The other time that has been developed strength low modulations spike trains, often referred in literature as 'common drive'. METHODS: relationships these methods systematically explored using both...
As society has moved past the initial phase of COVID-19 crisis that relied on broad-spectrum shutdowns as a stopgap method, industries and institutions have faced daunting question how to return stabilized state activities more fully reopen economy. A core problem is people their workplaces educational in manner safe, ethical, grounded science, takes into account unique factors needs each organization community. In this paper, we introduce an epidemiological model (the "Community-Workplace"...
COVID-19 forecasting models have been critical in guiding decision-making on surveillance testing, social distancing, and vaccination requirements. Beyond influencing public health policies, an accurate model can impact community spread by enabling employers university leaders to adapt worksite policies practices contain or mitigate outbreaks. While many such developed for at the national, state, county, city level, only a few workplaces universities. Furthermore, rarely validated against...
Genotype-phenotype modeling problems are often overcomplete, or ill-posed, since the number of potential predictors-genes, proteins, mutations and their interactions-is large relative to measured outcomes. Such datasets can still be used train sparse parameter models that generalize accurately, by exerting a principle similar Occam's Razor: When many possible theories explain observations, most simple is likely correct. We apply this philosophy drug response Type-1 Human Immunodeficiency...
Electroencephalograms (EEGs) provide a noninvasive way of measuring brainwave activity from sensors placed on the scalp. In this paper we present an approach to measure coupling, or synchrony, between various parts brain, critical for motor and cognitive processing, using wavelet coherence EEG signals. We argument, highlighting benefits as opposed regular Fourier based coherence, in context localizing short significant bursts non-stationary signals, which is insensitive. further highlight...
SUMMARY The sense of smell in dogs infected with canine distemper virus ( cdv ) was examined by use eeg olfactometry, behavioral and electro-olfactography. Infection confirmed a direct immunofluorescence technique 8 active cases suggested clinical history compatible 10 to 26 weeks earlier 6 cases. Pathologic alterations the olfactory mucosa 3 clinically affected light microscopy. found be associated anosmia lack recorded responses on electro-olfactogram signs acute from naturally acquired...
An analytical solution for pulsatile axial flow velocity waveforms in curved elastic tubes is presented. The result obtained by exact of linearized Navier-Stokes and tube motion equations a torroidal coordinate system. Fourier analysis used to divide the into constant oscillatory components which are separately considered. investigate effects curvature on volumetric waveforms, as would be measured Doppler ultrasound techniques. In typical human arteries, greatest exerted component at low...
The functional coupling between the primary motor cortex (M1) and supplementary area (SMA) in generation of internally paced versus externally cued rhythmic movements was explored using electroencephalography (EEG). This has important implications for study Parkinsonian patients who demonstrate decreased ability to perform movement tasks. In particular, temporal evolution coherence M1 SMA studied a recently developed time-frequency wavelet algorithm. As this approach is not reliant upon...
Clinical tests used to rate the severity of bradykinesia in patients with Parkinson's disease generally involve self-initiated and self-maintained repetitive movements (e.g. finger-tapping). This is based on evidence that movement impairment exacerbated by removal external timing cues or performance feedback (i.e. internally generated movements). Typically rated subjectively a clinician observation. Currently no clear means quantifying these types exist. Here we evaluate candidate measures...