Almond anthracnose was reported for the first time in Australia 1998 and has since been observed all of major almond-growing regions. The organism causing confirmed as Colletotrichum acutatum using taxon-specific polymerase chain reaction (PCR). Three main morphotypes C. from almond were identified (namely, pink, orange, cream colony color) optimum temperature mycelial growth representative isolates 25 degrees Australian more similar morphologically to pink subpopulation California than gray...

Minimally-invasive treatments for chronic total occlusions (CTO) involve the manual routing of a guidewire under fluoroscopy. However, navigation remains clinically challenging with high rates procedural failure and trauma to vessel. In this paper, we present proof-of-concept robotic capable acquiring forward-viewing ultrasound (US) images, thereby enhancing maneuverability through complex vasculature. We statics model based on Castigliano's theorem its validation by controlling notched...

The current standard of care for peripheral chronic total occlusions involves the manual routing a guidewire under fluoroscopy. Despite significant improvements in recent decades, navigation remains clinically challenging with high rates procedural failure and iatrogenic injury. To address this challenge, we present proof-of-concept robotic system forward-viewing ultrasound imaging to allow visualization maneuverability through complex vasculature.

Abstract Purpose Cardiovascular disease (CVD) is a leading cause of death worldwide, with coronary artery (CAD) accounting for nearly half all CVD deaths. The current gold standard CAD diagnosis catheter angiography (CCA), an invasive, expensive procedure. Computed tomography (CTCA) represents attractive non‐invasive alternative to CCA, however, CTCA requires gated acquisition CT data during periods minimal cardiac motion (quiescent periods) avoid non‐diagnostic scans. Current gating methods...

Peripheral artery disease (PAD) affects more than 200 million people globally. Minimally invasive endovascular procedures can provide relief and salvage limbs while reducing injury rates recovery times. Unfortunately, when a calcified chronic total occlusion is encountered, ~25% of fail due to the inability advance guidewire using view provided by fluoroscopy. To enable sub-millimeter, robotically steerable cross these occlusions, novel single-element, dual-band transducer developed that...

Abstract Background Approximately 500 000 patients present with critical limb ischemia (CLI) each year in the U.S., requiring revascularization to avoid amputation. While peripheral arteries can be revascularized via minimally invasive procedures, 25% of cases chronic total occlusions are unsuccessful due inability route guidewire beyond proximal occlusion. Improvements navigation would lead salvage a greater number patients. Purpose Integrating ultrasound imaging into could enable direct...

Direct estimation of 3D blood flow velocity components in vivo could provide important diagnostic information, as demonstrated by computational fluid dynamics. Several approaches have been proposed, however, direct intravascular has not despite the value dynamics for predicting major adverse cardiac events stable coronary artery disease. Given that minimally-invasive procedures are routinely performed these patients (e.g. side-viewing IVUS, FFR), a forward-viewing system allow 3D, with...

Coronary artery disease is a leading cause of mortality, however, it challenging to determine the functional significance given plaque, i.e. likelihood plaque rupture and major adverse cardiac events. One indicator vulnerability intra-plaque neovascularization. If neovascularization within could be visualized with intravascular ultrasound (IVUS) imaging, might possible stratify risk appropriate treatment for patients stable coronary (CAD) while patient undergoing diagnostic catheterization....

The ability to predict likelihood of plaque rupture could be used determine the course treatment in coronary artery disease. One indicator vulnerability is intra-plaque neovascularization, development blood vessels within plaque. In order visualize these with rotational, side-viewing intravascular ultrasound (IVUS), a new approach for imaging flow small proposed based on compounding adjacent angular acquisitions. This was evaluated tissue mimicking phantoms and ex vivo porcine using both...

Although minimally-invasive approaches such as stenting, atherectomy, and angioplasty represent more desirable alternatives to many open surgical procedures for restoring blood flow ischemic tissues, tortuous vasculature chronic total occlusions may lead iatrogenic injury failure of endovascular procedures, largely due the problem navigating complex environments using only side-viewing images from fluoroscopy. A forward-viewing steerable guidewire is proposed that could allow visualization...

Ultrasonic coda wave analysis techniques localize defects in fields such as seismography and nondestructive testing. In medical ultrasound, these might provide novel mapping of tissue properties diseases characterized by local fibrosis. this work, we present an approach for localizing variation scattering the diffuse regime with array transducer ultrasound. This estimates decorrelation is displaced 0.5 mm, allowing data acquisition at two slightly different spatial locations. An inverse...

Cardiovascular disease (CVD) accounts for 30% of deaths. The gold standard diagnosing coronary artery (CAD) is catheter-based angiography, which expensive and invasive. Computed tomography angiography (CTCA) represents an attractive alternative because it noninvasive computed widely available. However, CTCA subject to cardiac motion thus must be gated acquire images during the quiescent phase cycle. Gating based on mechanical using ultrasound has been demonstrated improve imaging performance...

More than 200 million people have peripheral artery disease globally. Minimally-invasive revascularization procedures can relieve pain, improve mobility, and salvage limbs. To navigation in these procedures, a transducer operating at two frequencies requiring only single cable was developed to provide forward-viewing imaging with high resolution close the penetration farther from for planning trajectory of submillimeter, robotically-steerable guidewire. For prototypes, center transducers...