Transcranial ultrasound imaging and therapy depend on the efficient transmission of acoustic energy through skull. Multiple previous studies have concluded that a large incidence angle should be avoided during transcranial-focused to ensure Alternatively, some other shown longitudinal-to-shear wave mode conversion might improve skull when is increased above critical (i.e., 25° 30°).The effect porosity at varying angles was investigated for first time elucidate why decreased in cases but...

Coronary artery disease (CAD) is one of the leading causes death globally. Currently, diagnosis and intervention in CAD are typically performed via minimally invasive cardiac catheterization procedures. Using current diagnostic technology, such as angiography fractional flow reserve (FFR), interventional cardiologists must decide which patients require can be deferred; 10% with stable incorrectly deferred using best practices. By developing a forward-viewing intravascular ultrasound...

This paper reports an integrated forward-view 2-axis MEMS scanner that enables ultrasmall 3D LiDAR for applications in micro-air vehicles (MAV). A new design of a pair vertically-oriented scanning is proposed and fabricated using innovative fabrication process. Such scanners are on silicon optical bench bent vertically to the substrate, thus forward scan realized without any beam-folding mirrors. The mirror plate 0.7 mm × mm. measured range reaches 17° both axes at only 4.5 V. resonance...

Abstract Purpose Cardiovascular disease (CVD) is a leading cause of death worldwide, with coronary artery (CAD) accounting for nearly half all CVD deaths. The current gold standard CAD diagnosis catheter angiography (CCA), an invasive, expensive procedure. Computed tomography (CTCA) represents attractive non‐invasive alternative to CCA, however, CTCA requires gated acquisition CT data during periods minimal cardiac motion (quiescent periods) avoid non‐diagnostic scans. Current gating methods...

Abstract Background Approximately 500 000 patients present with critical limb ischemia (CLI) each year in the U.S., requiring revascularization to avoid amputation. While peripheral arteries can be revascularized via minimally invasive procedures, 25% of cases chronic total occlusions are unsuccessful due inability route guidewire beyond proximal occlusion. Improvements navigation would lead salvage a greater number patients. Purpose Integrating ultrasound imaging into could enable direct...

Coronary artery disease (CAD) is a leading cause of death globally. Computed tomography coronary angiography (CTCA) noninvasive imaging procedure for diagnosis CAD. However, CTCA requires cardiac gating to ensure that diagnostic-quality images are acquired in all patients. Gating reliability could be improved by utilizing ultrasound (US) provide direct measurement motion; however, commercially available US transducers not computed (CT) compatible. To address this challenge, CT-compatible...

Large vessel occlusion (LVO) stroke, in which major cerebral arteries such as the internal carotid and middle supplying brain are occluded, is most debilitating form of acute ischemic stroke (AIS). The current gold standard treatment for LVO mechanical thrombectomy, however, initial attempts to recanalize these large, proximal fail up 75% cases, leading repeated passes that decrease likelihood success affect patient outcomes. We report design, fabrication, testing a 3 mm × forward-treating...

Coronary artery disease (CAD) is one of the leading causes death globally. Computed tomography coronary angiography (CTCA) a non-invasive procedure for diagnosis CAD. However, CTCA negatively affected by cardiac motion and thus requires use ECG data to ensure CT system only acquires during periods quiescence. Ultrasound-based gating can improve reliability providing more accurate quiescence detection. To identify time acquisition, 92-element phased array ultrasound transducer was designed...

Cardiovascular disease (CVD) accounts for 30% of deaths. The gold standard diagnosing coronary artery (CAD) is catheter-based angiography, which expensive and invasive. Computed tomography angiography (CTCA) represents an attractive alternative because it noninvasive computed widely available. However, CTCA subject to cardiac motion thus must be gated acquire images during the quiescent phase cycle. Gating based on mechanical using ultrasound has been demonstrated improve imaging performance...