Alayna P. Tackett

ORCID: 0000-0003-3818-141X
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About
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Research Areas
  • Smoking Behavior and Cessation
  • Obesity, Physical Activity, Diet
  • Behavioral Health and Interventions
  • Childhood Cancer Survivors' Quality of Life
  • Eating Disorders and Behaviors
  • Adolescent and Pediatric Healthcare
  • Biochemical Analysis and Sensing Techniques
  • Family Support in Illness
  • Nutrition, Health and Food Behavior
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Consumer Attitudes and Food Labeling
  • Cannabis and Cannabinoid Research
  • Media Influence and Health
  • Food Security and Health in Diverse Populations
  • Olfactory and Sensory Function Studies
  • Family and Disability Support Research
  • Risk Perception and Management
  • Air Quality and Health Impacts
  • Eosinophilic Esophagitis
  • Nicotinic Acetylcholine Receptors Study
  • Respiratory and Cough-Related Research
  • Food Safety and Hygiene
  • Noise Effects and Management
  • Asthma and respiratory diseases
  • Food Allergy and Anaphylaxis Research

University of Southern California
2020-2024

University of Oklahoma Health Sciences Center
2015-2024

The Ohio State University Wexner Medical Center
2023-2024

The Ohio State University
2023-2024

The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute
2024

USC Norris Comprehensive Cancer Center
2022-2023

Institute for Research, Education and Training in Addictions
2022

University of Oklahoma
2020-2021

Oklahoma State University Oklahoma City
2015-2020

OU Health Stephenson Cancer Center
2020

<h3>Introduction</h3> Electronic cigarettes’ (e-cigarettes) viability as a public health strategy to end smoking will likely be determined by their ability mimic the pharmacokinetic profile of cigarette while also exposing users significantly lower levels harmful/potentially harmful constituents (HPHCs). The present study examined nicotine delivery third- (G3) versus second-generation (G2) e-cigarette devices and users9 exposure select HPHCs compared with smokers. <h3>Methods</h3> 30...

10.1136/tobaccocontrol-2016-053041 article EN Tobacco Control 2016-10-11

<h3>Importance</h3> Alkaline free-base nicotine is bitter and a respiratory irritant. High-nicotine electronic cigarette (e-cigarette) products contain acid additives that change from to protonated salt chemical form, which could improve the sensory experience of vaping, particularly among never smokers unaccustomed inhaling nicotine. <h3>Objective</h3> To determine whether exposure e-cigarettes with vs formulations improves appeal vaping formulation effects differ by e-cigarette flavor ever...

10.1001/jamanetworkopen.2020.32757 article EN cc-by-nc-nd JAMA Network Open 2021-01-12

Rationale: Electronic cigarette (e-cigarette) use is highly prevalent among young adults. However, longitudinal data assessing the association between e-cigarette and respiratory symptoms are lacking. Objectives: To determine whether associated with development of in Methods: Data derived from PATH (Population Assessment Tobacco Health) study waves 2 (2014–2015), 3 (2015–2016), 4 (2016–2018), 5 (2018–2019). Young adults aged 18–24 years at baseline no disease or were included analyses....

10.1164/rccm.202107-1718oc article EN American Journal of Respiratory and Critical Care Medicine 2022-01-28

BACKGROUND AND OBJECTIVES Flavored non-tobacco oral nicotine products (eg, pouches and nontherapeutic gum, lozenges, tablets, gummies), are increasingly marketed in the United States. Prevalence of product use among adolescents is unknown. METHODS We calculated prevalence ever past 6-month pouches, other (ie, and/or e-cigarettes, cigarettes, hookah or waterpipe, cigars, cigarillos, snus high school students Southern California between September December 2021. Generalized linear mixed models...

10.1542/peds.2022-056586 article EN PEDIATRICS 2022-08-08

Rationale Electronic cigarette (e-cigarette) aerosol contains volatile aldehydes, including flavourings and oxidant metals with known pulmonary toxicity. Objectives To evaluate the associations of e-cigarette use symptoms wheeze, bronchitic shortness breath (SOB) across 4 years prospective data. Methods Participants completed questionnaires on respiratory past 30-day e-cigarette, cannabis in 2014 (wave 1; N=2094; mean age 17.3 years, SD=0.6 years). Follow-up information was collected 2015 2;...

10.1136/thorax-2022-218670 article EN Thorax 2023-08-15

To evaluate biochemically verified smoking status and electronic nicotine delivery systems (ENDS) use behaviors beliefs among a sample of customers from vapor stores (stores specializing in ENDS).A cross-sectional survey 215 adult store at four retail locations the Midwestern United States; subset participants (n = 181) also completed exhaled carbon monoxide (CO) testing to verify status.Outcomes evaluated included ENDS preferences, harm beliefs, behaviors, history current status.Most...

10.1111/add.12878 article EN Addiction 2015-02-12

To examine predictors of psychological functioning in college students with chronic illnesses.Participants (N = 1413) included 364 self-reported diagnoses asthma or allergies, 148 other illnesses (eg, epilepsy, type 1 diabetes), and 901 healthy students. Data were collected between November 2013 May 2015.Participants completed online measures psychosocial functioning, including illness uncertainty, intrusiveness, depression, anxiety.Students than allergies evidenced the greatest levels...

10.1080/07448481.2017.1312415 article EN Journal of American College Health 2017-03-31

Rationale Despite high prevalence of e-cigarette use (vaping), little is currently known regarding the health effects secondhand nicotine vape exposure. Objective To investigate whether exposure to associated with adverse respiratory symptoms among young adults. Method We investigated effect on annually reported wheeze, bronchitic and shortness breath in prospective Southern California Children Health Study cohort. Data were collected from study participants (n=2097) repeated annual surveys...

10.1136/thoraxjnl-2021-217041 article EN cc-by-nc Thorax 2022-01-10

Oral nicotine pouches may appeal to young adult current nicotine/tobacco users interested in alternative forms of that lack pulmonary exposure, but also non-users products. We used data from a 2020 remote digital survey an ongoing cohort study adults Southern California (aged 19–23) examine differences pouch perceptions and use willingness across statuses. Participants who had never (N = 1167) viewed text/imagery mass-marketed packaging advertising, then completed measures pouches, harm...

10.3390/ijerph19052685 article EN International Journal of Environmental Research and Public Health 2022-02-25

We examined the psychosocial characteristics of parents children with disorders sex development at early presentation to a clinic. Parental anxiety, depression, quality life, illness uncertainty and posttraumatic stress symptoms were assessed. Additionally we evaluated relationship assigned child gender parental outcomes.A total 51 ambiguous or atypical genitalia recruited from 7 centers specializing in treatment development. At initial assessment no had undergone genitoplasty. Parents...

10.1016/j.juro.2015.06.104 article EN The Journal of Urology 2015-07-19

Research regarding family adaption and resilience in children with chronic health conditions has resulted the development of a number theoretical models data‐driven psychosocial interventions field pediatric psychology, some which may not be well known science. These incorporate systems theory multiple resiliency factors within their framework to better describe complex process adaptation subsequent adjustment outcomes. In this article, three contemporary psychology are briefly reviewed...

10.1111/fare.12104 article EN Family Relations 2015-01-07

<h3>Importance</h3> Use of e-cigarettes (ECs) among youths has increased in recent years. e-Cigarette aerosol contains chemical constituents, such as diacetyl or benzaldehyde, which are known to affect the respiratory system. <h3>Objective</h3> To examine association between EC use and self-reported wheezing a cohort US adolescents. <h3>Design, Setting, Participants</h3> This study used data from waves 3 4 (October 19, 2015, January 3, 2018) Population Assessment Tobacco Health (PATH) study,...

10.1001/jamanetworkopen.2020.20671 article EN cc-by-nc-nd JAMA Network Open 2020-10-13

Abstract Introduction Novel, inexpensive disposable e-cigarettes widely sold in attractive flavors might be exempt from US federal regulations. To inform regulatory and public health priorities, this study examined young adult e-cigarette use uptake among existing tobacco users versus non-users possible correlates that could potential targets. Aims Methods Prospective cohort data were analyzed 2021. Among baseline (2018–2019) never (n = 1903; mean [SD]: 19.3 [0.8] years-old), we tested...

10.1093/ntr/ntab165 article EN Nicotine & Tobacco Research 2021-08-10

Concerns have been raised about the abuse liability of modern e-cigarettes that use acidic additives to form nicotine salts, making inhalation smoother than freebase nicotine.

10.1001/jamanetworkopen.2024.26702 article EN cc-by-nc-nd JAMA Network Open 2024-08-09

To present the preliminary psychometric properties of PAT2.0_GEN, a brief, caregiver completed screener psychosocial for children who were recipients kidney transplants. Caregivers 45 and adolescents with transplants PAT2.0_GEN PedsQL. Internal consistency predictive validity PAT2.0 examined. Total score was strong. subscales ranged from 0.31 to 0.82. Evidence supporting convergent observed; higher scores significantly associated lower caregiver- self-rated patient quality life poorer family...

10.1111/j.1399-3046.2011.01620.x article EN Pediatric Transplantation 2011-12-22

BackgroundThe potential for emerging tobacco products (ETPs) to be gateway further use among youth is of significant concern.PurposeTo examine various nicotine-containing on a tobacco-free college campus and whether the first product tried predicts subsequent use.MethodsUndergraduate students (N=1,304) at large university completed an online survey past/current cigarettes; smokeless (SLT); hookah; ETPs (dissolvables, snus, electronic cigarettes); nicotine replacement therapy (NRT). Data were...

10.1016/j.amepre.2014.09.018 article EN cc-by-nc-nd American Journal of Preventive Medicine 2014-12-17

Objectives Various organic acids are used to create nicotine salt formulations, which may improve the appeal and sensory experience of vaping electronic cigarettes (e-cigarettes). This clinical experiment examined effects partially highly protonated forms two formulations (nicotine lactate benzoate) versus free-base (no acid additive) on attributes e-cigarettes. Methods Current adult tobacco product users (n=116) participated in an online remote double-blind within-subject randomised...

10.1136/tc-2022-057553 article EN Tobacco Control 2023-01-02

Objective To investigate the relationship of illness uncertainty (IU) to global psychological distress (GPD) and posttraumatic stress symptomatology (PTSS) using a path analysis approach. Methods Participants were 105 caregivers ( M Age = 36.9 years, standard deviation [ SD ] 8.7) children 8.6 5.0) with newly diagnosed cancer. A model examined indirect direct effects each IU subscale on PTSS through GPD. Results The final accounted for 47.30% variance in PTSS, ambiguity facet had significant...

10.1093/jpepsy/jsv093 article EN Journal of Pediatric Psychology 2015-09-30

Background: Among adolescents and young adults (AYAs), “current use” of electronic cigarettes (e-cigarettes) is commonly defined as any use in the past 30 days. However, few studies have examined differences among those within this broad category. This study characteristics AYAs who used e-cigarettes at a low frequency (within last 3 months but &lt;6 days out days) high (6+ days). Methods: We conducted cross-sectional analyses 551 Ohio (15- to 24-year-olds) reported using an e-cigarette vape...

10.1177/29767342231214115 article EN Substance Use &amp Addiction Journal 2024-01-02

Chemotherapy and radiotherapy resistance are major obstacles in the long-term efficacy of head neck squamous cell carcinoma (HNSCC) treatment. Secondhand smoke (SHS) exposure is common has been proposed as an independent predictor HNSCC recurrence disease-free survival. However, underlying mechanisms responsible for these negative patient outcomes unknown. To assess effects SHS on cisplatin cancer cells, three distinct lines were exposed to sidestream (SS) smoke, main component SHS, at...

10.3390/ijms25021032 article EN International Journal of Molecular Sciences 2024-01-14

Objective: Tobacco use is elevated among individuals with eating disorders (EDs). Yet, further research needed to understand associations between cigarette and e-cigarette patterns ED symptomatology. To gain a more comprehensive understanding of tobacco EDs, this study characterized symptomatology patterns, including exclusive use, dual nonuse. Method: Young adults aged 18-24 years who self-reported cigarette, e-cigarette, dual, or nonuse (N = 2500) were recruited via Lucid, an online survey...

10.1080/10826084.2024.2330910 article EN Substance Use & Misuse 2024-03-27
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