A5087492973- Retinal Diseases and Treatments
- Retinal Imaging and Analysis
- Glaucoma and retinal disorders
- Retinal and Macular Surgery
- Ocular Diseases and Behçet’s Syndrome
- Retinal and Optic Conditions
- Intraocular Surgery and Lenses
- Ophthalmology and Visual Impairment Studies
- Ocular Infections and Treatments
- Artificial Intelligence in Healthcare and Education
- Insect and Arachnid Ecology and Behavior
- Plant and animal studies
- Insect and Pesticide Research
- Drug-Induced Ocular Toxicity
- COVID-19 diagnosis using AI
- Vibrio bacteria research studies
- Retinal Development and Disorders
- Vascular Malformations Diagnosis and Treatment
- Acupuncture Treatment Research Studies
- Acute Ischemic Stroke Management
- Corneal surgery and disorders
- Aquaculture disease management and microbiota
- Neuroscience and Neuropharmacology Research
- Plant Parasitism and Resistance
- Traditional Chinese Medicine Studies
University of Toronto
2017-2025
Kensington Health
2019-2024
University Health Network
2018-2024
Toronto Western Hospital
2018-2024
Beijing Tongren Hospital
2024
Capital Medical University
2024
Western University
2023
3M (United States)
2023
Qingdao University
2021
Affiliated Hospital of Qingdao University
2021
Ophthalmology is reliant on effective interpretation of multimodal imaging to ensure diagnostic accuracy. The new ability ChatGPT-4 (OpenAI) interpret ophthalmic images has not yet been explored.
To assess the performance of Chat Generative Pre-Trained Transformer-4 in providing accurate diagnoses to retina teaching cases from OCTCases.
Cannabinoid (CB)1 receptor inverse agonists inhibit food intake in animals and humans but also potentiate emesis. It is not clear whether these effects result from agonist properties or the blockade of endogenous cannabinoid signaling. Here, we examine effect a neutral CB1 antagonist, AM4113, on intake, weight gain, Neutral antagonist binding were confirmed HEK-293 cells transfected with human CB2 receptors. AM4113 had no forskolin-stimulated cAMP production at concentrations up to 630 nM....
ObjectiveTo evaluate the performance of an artificial intelligence (AI) large language model, ChatGPT (version 4.0), for common retinal diseases, in accordance with American Academy Ophthalmology (AAO) Preferred Practice Pattern (PPP) guidelines.DesignA cross-sectional survey study design was employed to compare responses made by established clinical guidelines.ParticipantsResponses AI were reviewed a panel three vitreoretinal specialists evaluation.MethodsTo investigate ChatGPT's...
The societies of ants, bees and wasps are genetically closed systems where queens only mate during a brief mating episode prior to their eusocial life males therefore provide with lifetime supply high-quality sperm. These ejaculates also contain number defence proteins that have been detected in the seminal fluid but function efficiency never investigated great detail. Here, we used honeybee Apis mellifera quantified whether is able combat infections fungal pathogen Nosema apis, widespread...
Social participation benefits health. We assessed the relationship between self-reported visual impairment (VI) and glaucoma versus seniors' social participation.Data from individuals aged ≥65 years responding to Canadian Community Health Survey Healthy Aging 2008/2009 (n = 16,369) was analyzed. Participation in eight activities by seniors with without VI or compared.Seniors had significantly reduced (p<0.05) sports/physical (18.0% vs. 33.6%), family/friendship outside household (39.7%...
Purpose: To investigate the association between baseline clinical characteristics of patients with diabetic macular edema (DME) and quantitative intravenous fluorescein angiography (IVFA) parameters. Methods: Consecutive DME presenting a central thickness (CMT) >310 μm were recruited from 2017-2023. Ultra-widefield IVFA images analyzed RETICAD algorithm to extract measures blood-retinal barrier (BRB) permeability, retinal perfusion, blood flow. Univariable multivariable regression models...
The queens of eusocial bees, ants and wasps mate only during a very short period early in life males therefore produce ejaculates consisting large numbers high quality sperm. Such extreme selection for fecundity resulted investing minimally into their somatic survival, including immune system. However, if susceptible are unable to protect reproductive tissue from infections, they compromise queen fitness transfer pathogens mating. We used the honey bee Apis mellifera investigated course...
Honey bee (Apis mellifera) males are highly susceptible to infections with the sexually transmitted fungal pathogen Nosema apis. However, they able suppress this parasite in ejaculate using immune molecules seminal fluid. We predicted that respond by altering fluid proteome minimize risk transmit queen and her colony. used iTRAQ isotopic labeling compare proteins from infected noninfected found N. apis resulted significant abundance changes 111 of 260 quantitated. The largest group...
Abstract Ionizing radiation can induce deoxyribonucleic acid (DNA) methylation pattern change, and ionizing radiation-induced oxidative damage may also affect DNA status. However, the influence of low-dose radiation, such as occupational exposure, on is still controversial. By investigating relationship between exposure changes, we evaluated whether was related to alterations then determined among level, status, in interventional physicians. The study population included 117 physicians...