A5054550183- GABA and Rice Research
- Genetic Mapping and Diversity in Plants and Animals
- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- Rice Cultivation and Yield Improvement
- Epigenetics and DNA Methylation
- Cancer, Hypoxia, and Metabolism
- Epilepsy research and treatment
- Polysaccharides and Plant Cell Walls
- Microbial Metabolites in Food Biotechnology
- Cancer Research and Treatments
- Enzyme Production and Characterization
- Plant Disease Resistance and Genetics
- Seaweed-derived Bioactive Compounds
- Coccidia and coccidiosis research
- Autophagy in Disease and Therapy
- Circular RNAs in diseases
- Cancer Mechanisms and Therapy
- Plant Genetic and Mutation Studies
- Animal Nutrition and Physiology
- Phytochemistry and Bioactive Compounds
- Sirtuins and Resveratrol in Medicine
- Parasitic Infections and Diagnostics
- RNA modifications and cancer
- Endoplasmic Reticulum Stress and Disease
China International Science and Technology Cooperation
2025
Gansu University of Traditional Chinese Medicine
2025
Gansu Provincial Hospital
2025
Guizhou Provincial People's Hospital
2025
First Affiliated Hospital of Henan University
2025
South China Agricultural University
2021-2024
Shanghai Jiao Tong University
2007-2024
Chengdu University of Traditional Chinese Medicine
2024
Zhuzhou Central Hospital
2024
Central South University
2024
The effects of mesenchymal stem cells (MSCs) and MSC-derived exosomes (MSC-exos) on serum metabolites intestinal microbiota in rats after liver trauma were discussed. Adult Wistar Albino assigned into control, model (liver trauma), MSCs, MSC-exos groups (n = 6). study examined changes the inflammatory environment tissues analyzed by histological examination analysis macrophage phenotypes. Alterations determined untargeted metabonomics, gut composition was characterized 16S rDNA sequencing....
Abstract Background In the oilseed crop Brassica napus (rapeseed), various metabolic processes influence seed oil content, quality, and biological yield. However, role of plastid membrane proteins in these traits has not been explored. Results Our genome-wide association study (GWAS) 520 B. accessions identified chloroplast protein-localized FATTY ACID EXPORTER 1-1 (FAX1-1) as a candidate associated with Seed transcript levels BnaFAX1-1 were higher cultivar high content relative to low-oil...
Colorectal cancer (CRC) is a common malignant tumor with high metastatic and recurrent rates. This study probes the effect mechanism of long non-coding RNA MIR31HG on progression CRC cells.Quantitative real-time PCR (qRT-PCR) was used to analyze expression miR-361-3p in tissues normal tissues. Gain- or loss-of-function assays were conducted examine roles MIR31HG, YY1 transcription factor (YY1) progression. 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay, colony...
Ubiquitination, a prevalent and highly dynamic reversible post-translational modification, is tightly regulated by the deubiquitinating enzymes (DUBs) superfamily.Among them, OTU Domain-Containing Ubiquitin Aldehyde-Binding Protein 1 (OTUB1) stands out as critical member of family, playing pivotal role tumor regulator across various cancers.However, its specific involvement in BLCA (BLCA) clinical significance have remained ambiguous.This study aimed to elucidate biofunctions OTUB1...
To observe the clinical efficacy of prophylactic use tibial extension stem in primary Total Knee Arthroplasty (TKA) patients with severe knee varus deformity and plateau bone defect, its effect on reducing rate prosthesis aseptic loosening. A total 398 who underwent TKA our hospital from August 2019 to June 2021 were collected. According strict inclusion/exclusion criteria, 55 (Hip-knee-ankle Angle, HKA ≤ 160°) defect finally included. The was used 22 standard 33 patients. general data,...
Objective To explore the effect of rehmanniae radix extract(RRE)on chondrocyte apoptosis in rabbit model knee osteoarthritis(KOA)by regulating miR-485-5p/heat shock protein 90 beta family member 1(Hsp90b1)axis.Methods New Zealand rabbits were randomly assigned into control,KOA,low-dose RRE,medium-dose RRE,high-dose RRE,celecoxib,high-dose RRE+antagonist control,and high-dose RRE+miR-485-5p antagonist groups,with 12 each group.Rabbits other groups except control group modeled for KOA with...
Autophagy is a highly conserved self-digestion process to promote cell survival in response nutrient starvation and other metabolic stresses eukaryotic cells. Dysregulation of this system linked with numerous human diseases, including cancers. ATG4B, cysteine protease required for autophagy, cleaves the C-terminal amino acid ATG8 family proteins reveal glycine which necessary conjugation phosphatidylethanolamine (PE) insertion autophagosome precursor membranes. However, mechanism governing...
In this study, we attempted to compare the efficacy and toxicity of concurrent chemoradiotherapy (CCRT) with radiotherapy alone (RT) for locoregionally advanced nasopharyngeal carcinoma (LANPC) in era intensity-modulated (IMRT) by meta-analysis.We searched databases, all randomized controlled trials meeting inclusion criteria were utilized a meta-analysis RevMan 5.3 based on Cochrane methodology.Fifteen studies found suitable criteria. CCRT not only significantly improved overall response...
In this study, we analyzed a water-soluble polysaccharide MP-I isolated from Mytilus coruscus. was obtained by hot-water extraction, anion-exchange and gel-permeation chromatography. Complete hydrolysis, periodate oxidation, methylation analysis, as well Fourier transform infrared spectroscopy (FTIR) nuclear magnetic resonance (NMR) were conducted to elucidate its structure. subjected investigate the protective effect on carbon tetrachloride (CCl(4)) induced liver damage in male Kunming...
The diagnostic value of SHOX2 DNA methylation in patients with lung cancer remains controversial. Thus, we performed a systematic review and meta-analysis to assess accuracy the lymph node, bronchial aspirates, pleural effusion, plasma, tumor tissue for cancer. We conducted comprehensive literature search PubMed, Ovid, Cochrane library, Web Science databases May 2015. sensitivity (SEN), specificity (SPE), positive likelihood ratio (PLR), negative (NLR), odds (DOR), summary receiver operating...
Which induction chemotherapy (IC) regimen followed by cisplatin-based concurrent chemoradiotherapy (CCRT) is the best choice among PF (cisplatin and 5-fluorouracil), TP (docetaxel cisplatin) TPF (docetaxel, cisplatin, 5-fluorouracil) remains controversial in locoregionally advanced nasopharyngeal carcinoma (LA-NPC). This Bayesian network meta-analysis investigated efficacy toxicity of these three common IC regimens attempted to find optimal regimen.We searched PubMed, Embase, Cochrane...