A5050658691- Diabetes Management and Research
- Diabetes Treatment and Management
- Pancreatic function and diabetes
- Ovarian function and disorders
- Hormonal and reproductive studies
- Gut microbiota and health
- Venous Thromboembolism Diagnosis and Management
- Metabolism, Diabetes, and Cancer
- Diabetes and associated disorders
- Hormonal Regulation and Hypertension
- Cardiovascular and exercise physiology
- Diagnosis and Treatment of Venous Diseases
- Blood properties and coagulation
- Blood Coagulation and Thrombosis Mechanisms
- Pituitary Gland Disorders and Treatments
- Pancreatic and Hepatic Oncology Research
- Reproductive Biology and Fertility
- Acute Ischemic Stroke Management
- Diet and metabolism studies
- Labour Market and Migration
- Abdominal vascular conditions and treatments
- Management and Organizational Practices
- Nutrition and Health Studies
- Clostridium difficile and Clostridium perfringens research
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Jagiellonian University
2014-2023
Krakow Cardiovascular Research Institute
2017-2022
University School of Physical Education in Kraków
2016-2021
Szpital Uniwersytecki w Krakowie
2019
Introduction Scientific data indicate a possible influence of gut microbiota on the development type 1 and 2 diabetes mellitus (T1DM T2DM, respectively). Sequence analysis 16S ribosomal RNA identified several hundred bacterial species intestinal ecosystem, most which cannot be cultured. Objectives We aimed to evaluate composition in adult patients with T1DM T2DM establish link between microbiological test results patients' clinical data. Patients methods examined DNA isolated from fecal...
Lipohypertrophy (LH) of subcutaneous tissue is an insulin-induced complication occurring in patients with diabetes. We aimed to define the prevalence LH and identify its risk factors type 1 diabetes (T1DM) treated continuous insulin infusion (CSII). The study included 79 consecutive CSII-treated T1DM patients. diagnose was based on ultrasonography (US) as a reference method, physical examination also performed. Clinical characteristics were available from medical records. median age 28 years...
SGLT2 inhibitors are a new class of oral hypoglycemic agents used in type 2 diabetes (T2DM). Their effectiveness maturity onset the young (MODY) is unknown. We aimed to assess response single dose 10 mg dapagliflozin patients with Hepatocyte Nuclear Factor 1 Alpha (HNF1A)-MODY, Glucokinase (GCK)-MODY, and diabetes. examined 14 HNF1A-MODY, 19 GCK-MODY, 12 patients. All studied individuals received morning added their current therapy To we analyzed change urinary glucose creatinine ratio serum...
Polycystic ovary syndrome (PCOS) affects 4-18% of women reproductive age. The number reports exploring the lipid profiles among PCOS patients and studied are limited. aim our study was to assess profile separately in lean non-lean with polycystic divided according hyperandrogenemia, defined as free androgen index (FAI)≥5. second compare respect hyperandrogenemia regularity menstruation cycles. We evaluated 232 from Department Endocrinological Gynecology, Jagiellonian University Medical...
Recently, several studies explored associations between type 1 diabetes (T1DM) and microbiota. The aim of our study was to assess the colonic microbiota structure according metabolic control in T1DM patients treated with insulin pumps. We studied 89 (50.6% women) at median age 25 (IQR, 22–29) years. Pielou’s evenness (p = 0.02), Shannon’s 0.04) Simpson’s diversity indexes 0.01), were higher glycosylated hemoglobin (HbA1c) ≥ 53 mmol/mol (7%). There no differences beta groups. A linear...
We aimed to estimate the impact of ingestion a pure protein load on glucose levels in T1DM patients treated with insulin pumps. examined 10 (6 females, mean age—32.3 years, HbA1c—6.8%) pumps equipped continuous monitoring system (CGMS). In Phase I, baseline infusion was optimized minimize differences fasting less than 30 mg/dL between any two time points 9 a.m. and 3 p.m. II, were exposed single load. CGMS record performed pattern defined for 6 hours each phase. The maximal level increment...
ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Milewicz T, Mrozińska S, Szczepański W, et al. Dysgerminoma and gonadoblastoma in the course of Swyer syndrome. Polish Journal Pathology. 2016;67(4):411-414. doi:10.5114/pjp.2016.65876. APA Milewicz, T., Mrozińska, S., Szczepański, W., Białas, M., Kiałka, & Doroszewska, K. (2016). Pathology, 67(4), 411-414. https://doi.org/10.5114/pjp.2016.65876 Chicago Tomasz, Sandra Wojciech Magdalena Marta Katarzyna Monika...
Post-thrombotic syndrome (PTS) is a common complication of deep vein thrombosis (DVT). Little known about the involvement adipokines in pathogenesis DVT. We evaluated whether can predict PTS. In prospective cohort study, 320 DVT patients aged 70 years or less were enrolled. Serum adiponectin, leptin and resistin levels measured three months since index first-ever After 2 years' follow-up PTS was diagnosed 83 309 available (26.9%) who had 13.9% lower adiponectin 16% higher compared with...
Background . Type 2 diabetes mellitus (T2DM) is determined by genetic and environmental factors. There have been many studies on the relationship between composition of gastrointestinal bacterial flora, T2DM, obesity. are no data, however, gut microbiome structure in monogenic forms disease including Maturity Onset Diabetes Young (MODY). Methods The aim investigation was to compare qualitative parameters colonic flora patients with HNF1A - MODY T2DM healthy individuals. 16S sequencing DNA...
Abstract Aim The impact of maturity onset diabetes the young (MODY) on quality life (QoL) has never been examined. We assessed disease QoL among patients with HNF1A-MODY and GCK mutation carrier status. Methods study included 80 89 gene carriers. also examined 128 type 1 (T1DM) for comparison. Diabetes-specific was using Audit Diabetes Dependent Quality Life questionnaire. Results GCK-MODY groups had similar mean age (41.7 vs. 38.0 years, respectively) BMI (24.1 24.3 kg/m 2 ), whereas T1DM...
In type 1 diabetes mellitus (T1DM), chronic hyperglycemia causes reactive oxygen and nitrogen species production. Exercise alters the oxidant-antioxidant balance. We evaluated aerobic capacity balance changes after maximum-intensity exercise in T1DM patients. The study involved 30 participants 23 controls. patients’ average age was 23.4 ± 5.1 years, with a body mass index of 24.3 3.1 kg m –2 satisfactory glycemic control. Among controls, respective values equaled 24.7 2.9 years 22.9 2.1 ....
Despite some evidence that indicates the evolution of polycystic ovary syndrome (PCOS) is related to activity endogenous opioid system, and concentration plasma β-endorphin levels can increase pain threshold, there are no studies which evaluate pressure threshold in PCOS women population.In 48 lean with 38 without this disorder β-endorphins PPT were measured.The level was higher group compared controls (15.28±2.49 pg/mL vs. 6.33±1.71 pg/mL, P<0.001). In PPTs measured on deltoid trapezius...
Regular physical activity for adults with type 1 diabetes mellitus improves cardiorespiratory fitness (CF) and quality of life. The aim our study was to evaluate clinical biochemical features that might be associated CF in a homogenous group who are all treated personal insulin pump (continuous subcutaneous infusion).
<b>Objective:</b> Glucose dependent insulinotropic peptide (GIP) belongs to the incretins which are responsible for 70% of insulin release after oral glucose intake. Its impaired secretion was noted in several conditions involving resistance, including polycystic ovary syndrome (PCOS), known as state with increased testosterone level. This paper considers a possible relationship between free androgen index (FAI) and basal well meal stimulated level GIP lean women affected by PCOS. To our...
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
Maturity-onset diabetes of the young (MODY) accounts for 1-2% all cases. Unfortunately, circa 90% MODY cases are misdiagnosed as type 1 or 2 diabetes. A proper genetic diagnosis based on automatic sequencing is crucial use a tailored treatment. However, this method still expensive and, thus, patients' selection testing should be performed precisely. In 2012, an easy-to-use tool was developed in Exeter, UK, to support British population. The aim study assess utility Probability Calculator...
Several lines of evidence have suggested that patients following venous thromboembolism (VTE) are at higher risk arterial (ATE). Prothrombotic fibrin clot characteristics were reported in individuals with cardiovascular factors. We investigated whether specific properties measured after 3-4 months anticoagulation characterize VTE subsequent ATE. enrolled 320 aged below 70 years (median age, 46). Ten lost to follow-up. ATE occurred 21 a median 54 (31-68) during follow-up 87.5 (incidence...
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)