- Stellar, planetary, and galactic studies
- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Astronomy and Astrophysical Research
- Acute Myocardial Infarction Research
- Galaxies: Formation, Evolution, Phenomena
- Pericarditis and Cardiac Tamponade
- Cardiovascular Function and Risk Factors
- Astrophysics and Star Formation Studies
- Cardiac tumors and thrombi
- Venous Thromboembolism Diagnosis and Management
- Atrial Fibrillation Management and Outcomes
- Acute Ischemic Stroke Management
- Antiplatelet Therapy and Cardiovascular Diseases
- Myasthenia Gravis and Thymoma
- Cardiac Structural Anomalies and Repair
- Cardiac Valve Diseases and Treatments
- Heart Rate Variability and Autonomic Control
- Ultrasound in Clinical Applications
- Long-Term Effects of COVID-19
- Health Systems, Economic Evaluations, Quality of Life
- Diabetes and associated disorders
- Astrophysical Phenomena and Observations
- Medical Imaging Techniques and Applications
- Cerebrovascular and Carotid Artery Diseases
Hospital Prof. Dr. Fernando Fonseca
2017-2024
Hospital Clínico San Carlos
2021-2024
Universidad Complutense de Madrid
2021-2024
Centro de Investigación en Red en Enfermedades Cardiovasculares
2024
Algarve Biomedical Center
2023-2024
Instituto de Investigación Sanitaria del Hospital Clínico San Carlos
2023
Instituto Superior Politécnico Gaya
2017
University of Cambridge
2006-2009
Institute of Astronomy
2006-2008
Lund University
2000-2007
Scientific research adopts qualitative and quantitative methodologies in the modeling analysis of numerous phenomena. The methodology intends to understand a complex reality meaning actions given context. On other hand, seeks obtain accurate reliable measurements that allow statistical analysis. Both offer set methods, potentialities limitations must be explored known by researchers. This paper concisely maps total seven methods five methods. A comparative most relevant adopted is done main...
We present a new public archive of light-motion curves in Sloan Digital Sky Survey (SDSS) Stripe 82, covering 99 deg right ascension from RA = 20.7 h to 3.3 and spanning 2.52 declination Dec -1.26 1.26 deg, for total sky area ~249 sq deg. 82 has been repeatedly monitored the u, g, r, i z bands over seven-year baseline. Objects are cross-matched between runs, taking into account effects any proper motion. The resulting catalogue contains almost 4 million stellar objects galaxies. photometry...
We report the discovery of a new Milky Way satellite in constellation Leo, identified data from Sloan Digital Sky Survey. It lies at distance ~180 kpc, and is separated by ≲3° another recent discovery, Leo IV. present follow-up imaging Isaac Newton Telescope spectroscopy Hectochelle fiber spectrograph Multiple Mirror Telescope. V's heliocentric velocity ~173.3 ± 3.1 km s−1, offset ~40 s−1 that A simple interpretation kinematic both objects may lie on same stream, although implied orbit only...
Over the last decade, steady progress has been made in ability to assess coronary stenosis relevance by merging computerised analyses of angiograms with fluid dynamic modelling. The new field functional angiography (FCA) attracted attention both clinical and interventional cardiologists as it anticipates a era facilitated physiological assessment artery disease, without need for intracoronary instrumentation or vasodilator drug administration, an increased adoption ischaemia-driven...
We present the largest and most detailed survey to date of stellar populations in outskirts M31 based on homogeneous analysis 14 deep Hubble Space Telescope Advanced Camera for Surveys (HST/ACS) pointings spanning range 11.5 kpc ≲ Rproj 45 kpc. Many these sample coherent substructure discovered course Isaac Newton Wide Field (INT/WFC) imaging while others more diffuse structure extended disk. conduct a quantitative comparison resolved fields identify several striking trends. The...
We present the first results from our survey of stellar substructure in outskirts M31 using Advanced Camera for Surveys on board Hubble Space Telescope. discuss populations associated with five prominent overdensities discovered during course panoramic ground-based imaging Isaac Newton Telescope Wide-Field Camera; a sixth pointing targets region "clean" halo. The color-magnitude diagrams, which contain between ≈10,000 and 90,000 stars reach 4 mag below horizontal branch, reveal clear...
Investigate age-related changes in coronary microvascular function, its effect on hyperemic and non-hyperemic indices of stenosis relevance, prognostic implications.
Patients with acute pulmonary embolism are at intermediate-high risk in the presence of imaging signs right ventricular dysfunction plus one or more elevated cardiac biomarker. We hypothesised that patients two biomarkers and have a worse prognosis than those biomarker dysfunction.We analysed cumulative 525 intermediate (intermediate-high = 237) presenting emergency department centres. Studied endpoints were composites all-cause mortality and/or rescue thrombolysis 30 days (primary endpoint;...
The influence of age-dependent changes on fractional flow reserve (FFR) or instantaneous wave-free ratio (iFR) and the response to pharmacological hyperaemia has not been investigated.We investigated impact age these indices.This is a post hoc analysis ADVISE II trial, including total 690 pressure recordings (in 591 patients). Age-dependent correlations with FFR iFR were calculated adjusted for stenosis severity. Patients stratified into three terciles. hyperaemic adenosine, as difference...
We present deep Hubble Space Telescope ACS observations of the G1 clump, a distinct stellar overdensity lying at ∼30 kpc along southwestern major axis M31, close to globular cluster (from work Ferguson and coworkers). Our well-populated color-magnitude diagram reaches ∼7 mag below red giant branch tip with 90% completeness, allows detection various morphological features that can be used derive detailed constraints on age metallicity constituent population. find is best described by...
To investigate the effect of aging on coronary stenosis functional assessment with fractional flow reserve (FFR) and instantaneous wave-free ratio (iFR).Limited data exist regarding impact patient age these pressure indices.We analyzed 514 patients interrogated intravascular physiology. The influence FFR, iFR, microcirculation-related indices was investigated. Vessel-oriented composite outcome (VOCO) assessed in FFR-based deferred population according to (CFR), age.FFR increased (r = 0.128,...
Photon-counting silicon avalanche photo-diodes (APDs) offer very high quantum efficiency, and might eventually replace photocathode detectors in high-speed photometry of astronomical objects. Laboratory studies have been performed on both passively actively quenched APDs. Peculiarities APDs include that the dark signal may exhibit bistability, with count rate jumping between discrete levels. Following any photon detection, detector itself emits some light, which be confusing under certain...
To evaluate the impact of a real-time visual feedback device on Chest comparison (CCs) rate and depth delivered by healthcare professionals.In simulated scenario sensor was placed manikin's chest connected to defibrillator which provided CCs. Thirty-two professionals performed sequentially 5 cycles 30 CCs without (FeedOFF) with (FeedON) feedback. between 50 60mm 100 120cpm were considered optimal.Visual resulted in significant increase proportion optimal (median 8.7 [interquartile range...
The Internet is a fundamental aspect of health information. However, the absence quality control encourages misinformation. We aim to assess relevance and acute myocardial infarction videos shared on YouTube (www.youtube.com) in Portuguese.We analyzed 1,000 corresponding first 100 search results using following terms (in Portuguese): "cardiac + arrest"; "heart attack"; thrombosis"; "coronary "infarction - brain", "myocardial infarction" "acute infarction". Irrelevant (n=316), duplicated...
Managing coronary saphenous vein graft failure has remained an unmet need since the inception of interventional cardiology. The present case constitutes opportunity to revisit percutaneous strategies treat failure, providing a travel though and showing contemporary approach this problem. (Level Difficulty: Intermediate.)
Several scoring systems have been developed for risk stratification in patients with acute pulmonary embolism (PE). The Pulmonary Embolism Severity Index (PESI) and its simplified version (sPESI) are among the most used, however high number of variables hinder application. Our aim was to derive an easy-to-perform score based on simple parameters obtained at admission predict 30-day mortality PE patients.Retrospective study 1115 from two institutions (derivation cohort n=835, validation...
Abstract Background Managing high thrombotic burden in the context of myocardial infarction remains a challenging scenario. Case summary A 51-year-old male was admitted for subacute inferior with persistent chest pain. Emergent coronary angiography showed an ostial–proximal occlusion large ectatic right artery. Several balloon inflations were performed that not able to improve distal TIMI flow beyond II. With intent vaporizing remaining thrombus, Excimer Laser Coronary Angioplasty favourable...