A5000653445- Pneumocystis jirovecii pneumonia detection and treatment
- Cytomegalovirus and herpesvirus research
- Pediatric health and respiratory diseases
- Immunodeficiency and Autoimmune Disorders
- Herpesvirus Infections and Treatments
- HIV, TB, and STIs Epidemiology
- Respiratory viral infections research
- Tuberculosis Research and Epidemiology
- Respiratory and Cough-Related Research
- Parvovirus B19 Infection Studies
- Toxoplasma gondii Research Studies
- Pneumonia and Respiratory Infections
- Parasitic Infections and Diagnostics
- Hepatitis C virus research
- Virology and Viral Diseases
- Viral Infections and Immunology Research
- Neonatal and fetal brain pathology
- Hepatitis B Virus Studies
- Viral-associated cancers and disorders
- Urticaria and Related Conditions
- Dermatological and COVID-19 studies
- Dermatology and Skin Diseases
- Human Health and Disease
- Bacterial Infections and Vaccines
- Immune Cell Function and Interaction
Gamalei Institute of Epidemiology and Microbiology
2015-2024
Ministry of Health of the Russian Federation
2019-2021
National Research Centre
2018-2019
Infection caused by the Epstein-Barr virus (EBV) is more common in children and transmitted through contact with saliva. The role of adults epidemic process has not been sufficiently studied. goal to study catarrhal phenomena spread EBV during seasonal rise incidence upper respiratory tract infections (URTI). Materials methods . In season 201 9—2020, 226 people symptoms (140 86 children) were examined PCR for presence other URTI pathogens their nasal oropharyngeal smears. Results....
Objective. The aim of the study is to investigate peculiarities changes in immune status individuals with active and latent forms herpesvirus infections. Herpesvirus infections are an urgent problem modern health care.
 Materials methods. prospective longitudinal cohort included 92 permanent blood donors who were examined twice at 6-month intervals for presence specific IgM IgG antibodies antigens herpes simplex viruses 1, 2, Epstein-Barr, cytomegalovirus, human type 6, as well humoral...
The article is devoted to study the etiological role of herpes viruses in infectious and somatic pathology children (n = 770) using complex methods laboratory diagnostics. Determined leading HSV with neuroinfections (12,7%) during primary infection intrauterine (29,0%) its reactivation. It shown that 50,9% cases, diagnosis «infectious mononucleosis» confirmed by detection markers acute EBV-infection, 20,0%, it was replaced mononucleotides syndrome discovered CMV-infection, 18,1% —...
The paper presents the results of comprehensive examination and treatment in 514 children who have developed a persistent cough lasting for more than 3 weeks after acute respiratory disease. cause coughing was concurrence infectious somatic diseases majority cases (62.8%). Among diseases, there were most common allergic organs (32.4%) ENT (27.4%). 311 (60.5%) found to markers Mycoplasma (43.9%), herpesvirus (42.2%), Pneumocystis (21.4%), Chlamydia (6.25%) infections as mono- or mixed...
The purpose of the study To estimate prevalence markers herpesvirus infections and pneumocystosis in patients hematological department. identify whether contamination with hepatitis B C (HBV, HCV) affects on activation opportunistic (OIs). Materials methods There were examined 94 department, including 48 HBV infection 46 cases without them. Obtained results Markers acute OIs (simple herpes virus type 1- 6,4%, EBV - 14,9%, CMV Human Herpesvirus 6- 13,8% 33,0% pneumocystosis) determined more...
The article presents the role of herpesviral infections caused by herpes simplex virus (HSV), Epstein-Barr (EBV), cytomegalovirus (CMV) and human herpesvirus type 6 (HHV-6) in 36 children with recurrent respiratory tract diseases at age from 1 to 18 years. Blood sera blood cells were studied using ELISA, Indirect reaction immunofluorescence Rapid culture method. It was found that all (100%) infected HSV, EBV, CMV HHV-6. Most often — 19 (52.8%) signs active HHV-6 revealed. In same number...
The results of previous studies suggest the involvement herpes viruses in development atopic dermatitis and psoriasis, but there is no convincing evidence. Aim study was to evaluate role active herpesvirus infection exacerbation psoriasis. Material methods. analysis incidence infectious mononucleosis, genital herpes, cytomegalovirus infection, skin subcutaneous tissue diseases, dermatitis, psoriasis Russia 2000–2020 carried out. 92 blood donors 97 patients with diseases (44 53 psoriasis)...
Aim. The investigate the current manifestations of symptomatic and inapparent epidemic process Epstein-Barr infection, as well identification its features in women childbearing age newborns. Materials methods. We performed an epidemiological analysis incidence infectious mononucleosis HIV infection Russian Federation. trends morbidity distribution across territories groups was studied. A study made on frequency detection markers age, incl. HIV-infected pregnant Results. It has been...
Human herpes virus type 6 (HHV-6) is the etiological agent of plenty diseases. The form developing pathology depends on localization in T-lymphocytes and type: HHV-6A or HHV-6B, but identification possible by nucleotide sequence only. In Russia, researching typing HHV-6 are conducted Moscow St. Petersburg mainly, results discordant. Also prevalence HHV-6B among various population groups particular interest.
The study is devoted to the clinical examination of frequently ill children in North-Eastern regions Russia and laboratory detection markers herpesvirus infections, as well pneumocystosis establishment relationship with their immune status. 62 aged 8—15 years were examined. Samples serum blood cells, sputum on infections by ELISA, indirect immunofluorescence reaction rapid culture method studied. Assessment humoral immunity determination circulating complexes was performed solid-phase enzyme...
Objective. To evaluate the involvement of P. jirovecii in infectious and other diseases children adults with immunosuppression various origin. assess risk infection jirovecii, pneumocystosis its spread by healthcare workers. Materials Methods. An analysis results a study 1,446 samples peripheral blood sera from patients, both adults, who were treated hospitals profiles Moscow represented an increased group for pneumocystosis. IgM IgG class antibodies determined enzyme immunoassay (ELISA)....
The study showed a high prevalence of markers herpesvirus infections among mothers — from 71% to 98% HSV, EBV and CMV 29% 58% HHV-6 infection. HSV remains the most common etiological agent intrauterine herpesviruses active infection caused by this virus were found in 28.3% samples. difficulty determining source absence data early stages pregnancy is presented on 4 out 10 cases Markers pneumocystic detected only mothers: group with children under age 21 days 21—27% cases, aged 22 28 15—21%....
The value of human herpes virus type 6 (HHV-6) in the structure seizures 114 children three groups patients: with neuroinfections, epilepsy and febrile convulsions was studied. Determination HHV-6 by polymerase chain reaction acute period disease is a reliable sign (p < 0.001), most often diagnosed group (53.8%). Recovery caused HHV-6, observed only 28% cases,38.8% patients outcome expand epilepsy.
This article covers the issues of pathogenesis, diagnostics, clinical manifestations and treatment CMV infections at perinatal infection
Objective. To determine the detection rates of HHV-6A and HHV-6B compared to other herpes viruses in children different age groups. Materials Methods. A total 128 patients with symptoms respiratory viral infections (RVI) aged from 1 16 years 101 otherwise healthy children. comprehensive examination patients, including ELISA, indirect immunofluorescence assay, rapid culture method, PCR, determination nucleotide sequences HHV-6 was performed. Children positive for markers (antibodies, early...
The paper presents the results of comprehensive examination and treatment in 514 children who have developed a persistent cough lasting for more than 3 weeks after acute respiratory disease. cause coughing was concurrence infectious somatic diseases majority cases (62.8%). Among diseases, there were most common allergic organs (32.4%) ENT (27.4%). 311 (60.5%) found to markers Mycoplasma (43.9%), herpesvirus (42.2%), Pneumocystis (21.4%), Chlamydia (6.25%) infections as mono- or mixed...