ABSTRACT Background Situs inversus totalis (SIT) is present in approximately 40%–50% of patients with primary ciliary dyskinesia (PCD). We evaluated the relationships between novel genetic results and clinical radiological characteristics PCD SIT. Methods The study included 48 diagnosed Demographic features, disease‐related scores (Bhalla, Primary Ciliary Dyskinesia Rule [PICADAR], American Thoracic Society [ATS]), analyses were retrospectively assessed. Results median age was 13 (6.5–16)...

Abstract Aim The aim of this study is to determine the effect vitamin D replacement therapy on sleep habits in restless legs syndrome (RLS) patients with deficiency. Methods was conducted between September 1, 2018, and 2019, at Pediatrics outpatient clinic Bezmialem Vakif University. 46 cases RLS 43 healthy controls these dates were included study. Children’s Sleep Habits Questionnare filled out retrospectively by parents. Results While supplementation given 20 children who found have...

Exposure to secondhand smoke is too common in many countries. The mechanism of the detrimental effects passive smoking on childhood health, however, poorly described. purpose this study was therefore examine effect total antioxidant status (TAS), oxidant (TOS), and paraoxonase-1 children compared with healthy non-passive smokers.This included 40 adolescents passively exposed cigarette (as verified urine cotinines) age- gender-matched controls not regularly smoke. TAS, TOS, were all measured,...

We aimed to assess the impact of COVID-19 on asthma exacerbations and compare severity symptoms SARS-CoV-2 infection asthmatic children with those healthy children.The clinical course was compared among 89 84 age- gender-matched. Demographic factors, asthma, duration presence atopy, type treatment, compliance treatment in determine risk factors for severe exacerbation during were evaluated retrospectively. characteristics, symptoms, complaints, hospitalization rates statistically between two...

Malnutrition continues to be a leading cause of stunted growth in many countries. This study aimed investigate serum nesfatin-1 and orexin-A levels underweight children the potential correlations these with anthropometric nutritional parameters.The enrolled 44 prepubertal (between 2 12 years age) thinness grades 1-3 41 healthy age- gender-matched children. The demographic, clinical laboratory parameters including concentrations were compared between two groups. biochemical investigated....

Abstract Objectives It is unclear whether body weight status (underweight/normal weight/overweight/obese) associated with allergic disease. Our objective was to investigate the relationship between (body mass index; BMI) and atopic disease in prepubertal children, compare children diseases non healthy children. Methods A prospective cross sectional study of 707 aged 3–10 years performed; participants were 278 physician-diagnosed (allergic rhinitis asthma) (serum total IgE level >100 kU/l...

Free radicals found in cigarette smoke can harm all tissues and cellular structures the human body. Passive smoking increases free radical production, leads to depletion of antioxidants oxidative stress which causes lipid peroxidation. Many studies have been conducted determine effects passive on antioxidant enzymes levels adults, but pediatric this topic are few. In our study, we compared antioxidants, oxidants, total LDL cholesterol children exposed with a healthy control group that was...

Abstract Background The present study aims to assess psychiatric diagnoses in children with psychogenic and functional breathing disorders (PFBD), which consist of cough, throat‐clearing tics, sighing dyspnea, compare them a control group without any diagnosis chronic medical problems. Methods participants 52 PFBD 42 Psychiatric were assessed via semistructured interviews both groups. Results two groups did not differ on age (PFBD 11.25 ± 2.61, 11.17 2.58; t = 0.14, P .88) or sex (48.1% the...

Amaç: Otitin komplikasyonu olarak beyin absesi sıklığı azalmışıtır. Sinüzitten kaynaklanan ise hem yetişkinlerde çocuklarda önemli bir yer teşkil etmektedir. Bu çalışmada otojenik ve sinojenik kaynaklı 6 vakası sunuyoruz.Gereç yöntem: Ocak 2013 ile Mayıs 2017 tarihleri arasında intrakraniyal abse yatırılan çocukların verileri geriye dönük değerlendirildi. Önceden belirleyici faktörler, klinik bulgular prognoz belirlendi.Bulgular: İntrakraniyal bulunan 8 çocuk 6’sı otogenik / veya sinogenik...

The diagnosis of childhood tuberculosis is difficult and most the patients are diagnosed clinically. objective this study to reveal diagnostic therapeutic components pulmonary analyze changes that occurred in our country over years.All with between 2006 2016 were included. Demographic characteristics, treatment outcomes recorded followed up prospectively.A total 492 included study. 97% had Bacillus Calmette-Guerin vaccine, 36% microbiologically-confirmed 64% clinically-proven tuberculosis....

Background: Published data on the correlations of bronchoscopy findings with microbiological, radiological, and pulmonary function test results in children noncystic fibrosis (CF) bronchiectasis (BE) are unavailable. The aims this study were to evaluate relationships between Bronchoscopic appearance secretion scoring, microbiological growth, radiological severity level, tests patients non-CF BE. Methods: Children BE identified collected over a 6-year period. Their medical charts radiologic...

Abstract Purpose The most important cause of mortality and morbidity in acute rheumatic fever (ARF) is carditis heart disease (RHD). aim this study was to identify markers that may be indicators chronic inflammation whole blood analyses pediatric patients with RHD who regularly received secondary deposilin prophylaxis. Methods In our study, 100 children ARF aged between 4 18 years were followed up the cardiology outpatient clinic patient group. control group consisted healthy same sex age as...

Innate-like T lymphocytes are a recently defined group of cells comprising mainly mucosa-associated invariant (MAIT) cells. The relationship between MAIT and childhood asthma is controversial. In this study, we aimed to determine the role in patients with allergic (AA) nonallergic (NAA). This first study compare ratios these AA NAA.

Systemic iron homeostasis is regulated by the interaction of peptide hormone, hepcidin and exporter, ferroportin. The objective was to investigate relationship between consumption cow's milk deficiency anemia in children 2–10 years old its association with hepcidin-25 ferroportin concentrations. study population consisted 187 prepubescent similar ideal body weight (IBW:90–120%); 82 (37girls 45boys; 4.27 ± 0.28 years) 105 (47girls 58boys; 4.25 0.34 healthy age-sex-matched controls. Serum...

Abstract : We aim to evaluate how vitamin D-containing supplements affect the D status of children 1–3 years old and assess variation concentrations across different seasons. This retrospective study included a review medical reports 1035 patients (aged years) who presented our hospital between October 2011 2013. The were divided into 3 groups: Group 1: those supplemented with Gender distribution was not statistically three groups (p=0.38). had taken significantly higher levels compared...

Girişİdrar yolu enfeksiyonu (İYE), otitis mediadan sonra çocuklarda görülen ikinci en yaygın bakteriyel enfeksiyondur.Yaşamın ilk 7 yılında erkeklerin yaklaşık % 2'sini ve kızların 8'ini etkiler (1-3).Çocukluk çağında İYE akut dönemde böbrek hasarı, bakteriyemi, ürosepsis hatta ölüme neden olabilirken; uzun vadede hipertansiyon, proteinüri, skarı yetmezliği gibi klinik sonuçlarla da ilişkilidir.Bu nedenle, tanısı alan çocuklar hızlı doğru tedavi edilmelidir (4, 5).Escherichia coli, İYE'den...

This study was performed to investigate the gene polymorphisms of myeloperoxidase (MPO) enzyme and determine whether MPO influence response iron therapy in pediatric patients with deficiency anemia (IDA). In this case-control study, 50 Turkish children IDA healthy controls were enrolled. Three alleles selected for genotyping study: GG, AG, AA. The relationships analyzed compared controls. Pretreatment posttreatment laboratory parameters patient group. There a significant difference between...

GIRIS ve AMAC: Bu calismanin amaci, kistik fibrosis disi bronsektazi (KFDB) hastaligi olan herhangi bir olmayan cocuklarin agiz hijyeni, periodontal sagligi ile ilgili parametreleri karsilastirmaktir. YONTEM GERECLER: calisma Nisan 2015-Temmuz 2015 tarihleri arasinda yapilan 0-16 yas arasi 151 cocugun dahil oldugu kesitsel calismadir. Calisma grubu cocuktan (KFDB 111 cocuk, veya kronik 40 cocuk) olusturuldu. KFDB hastalarinin tek seferlik oral muayenesi yapildi panoramik radyografik...

Aim: This study aimed to compare the morbidity and mortality of preterm term neonates who were admitted neonatal intensive care unit. Material Method: In this study, we compared problems rates 250 late-preterm newborns (gestational age: 34 0/7 -36 6/7 weeks) 37-42 Neonatal Intensive Care Unit Zeynep Kamil Women Children's Diseases Training Research Hospital from 01.05.2009 01.05.2010.Results: Respiratory distress, feeding problems, hypoglycemia, hypothermia, necrotizing enterocolitis,...