Megan S. Motosue

ORCID: 0000-0003-3846-2262
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About
Contact & Profiles
Research Areas
  • Food Allergy and Anaphylaxis Research
  • Allergic Rhinitis and Sensitization
  • Drug-Induced Adverse Reactions
  • Asthma and respiratory diseases
  • Childhood Cancer Survivors' Quality of Life
  • Contact Dermatitis and Allergies
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Immunodeficiency and Autoimmune Disorders
  • Neonatal Respiratory Health Research
  • Eosinophilic Esophagitis
  • Antimicrobial Resistance in Staphylococcus
  • Hematopoietic Stem Cell Transplantation
  • Acute Lymphoblastic Leukemia research
  • Congenital Diaphragmatic Hernia Studies
  • Human Health and Disease
  • Blood disorders and treatments
  • Monoclonal and Polyclonal Antibodies Research
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • HIV/AIDS drug development and treatment
  • Vitamin D Research Studies
  • Metabolism, Diabetes, and Cancer
  • Parathyroid Disorders and Treatments
  • Coagulation, Bradykinin, Polyphosphates, and Angioedema
  • Respiratory and Cough-Related Research
  • Autoimmune Bullous Skin Diseases

University of Hawaiʻi at Mānoa
2008-2023

University of Hawaii System
2021-2023

Kaiser Permanente
2022

Kaiser Foundation Hospital
2021

Mayo Clinic
2015-2018

Mayo Clinic in Florida
2017-2018

Children's Center
2017

Mayo Clinic in Arizona
2016

Santa Clara Valley Medical Center
2013

University of Tennessee Health Science Center
2012

The true global scale of anaphylaxis remains elusive, because many episodes occur in the community without presentation to health care facilities, and most regions have not yet developed reliable systems with which monitor severe allergic events. robust data sets currently available are based largely on hospital admissions, limited by inherent issues misdiagnosis, misclassification, generalizability. Despite this, there is convincing evidence a increase rates all-cause anaphylaxis, driven...

10.1016/j.jaip.2019.11.027 article EN cc-by The Journal of Allergy and Clinical Immunology In Practice 2019-11-28

Food is the leading cause of anaphylaxis in children seen emergency departments United States, yet data on department visits and hospitalizations related to food-induced are limited. The objective our study was examine national time trends pediatric anaphylaxis-related hospitalizations.We conducted an observational using a administrative claims database from 2005 through 2014. Participants were younger than 18 years with visit or hospitalization for anaphylaxis. Outcome measures included...

10.1111/pai.12908 article EN Pediatric Allergy and Immunology 2018-04-17

To measure longitudinal changes in body mass and composition survivors of childhood hematologic malignancies after allogeneic hematopoietic stem-cell transplantation (HSCT).Body index (BMI) was analyzed 179 by category (underweight, healthy-weight, overweight, obese) z score. Fat lean measured dual-energy x-ray absorptiometry as scores.Over a median 6.6 years follow-up, BMI scores diminished significantly (0.32 pre-HSCT v -0.60 at 10 post-HSCT; P < .001). Mean for fat stayed within...

10.1200/jco.2011.40.0457 article EN Journal of Clinical Oncology 2012-10-02

Aqueous extracts or juice from unripened fruit of Momordica charantia (bitter melon) has traditionally been used in the treatment diabetes and its complications. Insulin resistance is characterized by significant down-regulation hepatic insulin signalling as documented attenuated phosphorylation receptor (IR), IR substrates 1 2, phosphoinositide-3 kinase, protein kinase B, over-expression phosphotyrosine phosphatase 1B. We recently demonstrated that bitter melon (BMJ) a potent inhibitor apoB...

10.1017/s0007114508937430 article EN British Journal Of Nutrition 2008-03-05

Abstract BACKGROUND: Although whole lung irradiation is used to treat pulmonary metastases of pediatric solid malignancies, few studies have addressed its long‐term consequences. METHODS: The authors conducted a retrospective study longitudinal changes in 171 function tests (PFTs) and their relation with clinical features 48 survivors malignant tumors treated irradiation. RESULTS: active respiratory symptoms were seen only 9 patients (18.8%), abnormalities forced vital capacity (FVC; 58.3%),...

10.1002/cncr.26371 article EN Cancer 2011-07-28

Introduction: Epinephrine is the treatment of choice for anaphylaxis. We surveyed emergency department (ED) health care providers regarding 2 methods intramuscular (IM) epinephrine administration (autoinjector and manual injection) management anaphylaxis allergic reactions identified provider perceptions preferred method medication delivery.Methods: This observational study adhered to survey reporting guidelines. It was performed through a Web-based completed by at an academic ED. The...

10.5811/westjem.2016.8.30505 article EN cc-by Western Journal of Emergency Medicine 2016-11-01
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