A5023373562- Catalysts for Methane Reforming
- Advanced Proteomics Techniques and Applications
- Catalytic Processes in Materials Science
- Catalysis and Hydrodesulfurization Studies
- Mass Spectrometry Techniques and Applications
- Metabolomics and Mass Spectrometry Studies
- CO2 Reduction Techniques and Catalysts
- Ammonia Synthesis and Nitrogen Reduction
- Biodiesel Production and Applications
- Advanced Chemical Sensor Technologies
- Catalysis and Oxidation Reactions
- Nanomaterials for catalytic reactions
- Electrocatalysts for Energy Conversion
- Global Energy Security and Policy
- Analytical Chemistry and Chromatography
- Carbon Dioxide Capture Technologies
- nanoparticles nucleation surface interactions
- Genomics and Phylogenetic Studies
- Fungal and yeast genetics research
- Crystallization and Solubility Studies
- Global Energy and Sustainability Research
- Reservoir Engineering and Simulation Methods
- Thermochemical Biomass Conversion Processes
- Coal and Coke Industries Research
- X-ray Diffraction in Crystallography
Haldor Topsoe (Denmark)
2015-2023
Eurofins (Denmark)
2022
Technical University of Denmark
2009-2016
University of Southern Denmark
2001-2009
Institute of Bioinformatics
2008-2009
Utrecht University
2008-2009
Johns Hopkins University
2008
Canadian Energy Research Institute
2003
Nordisk Fond for Miljø og Udvikling
1999-2000
Danish Gas Technology Centre (Denmark)
2000
Mass accuracy is a key parameter of mass spectrometric performance. TOF instruments can reach low parts per million, and FT-ICR are capable even greater provided ion numbers well controlled. Here we demonstrate sub-ppm on linear trap coupled via radio frequency-only storage (C-trap) to the orbitrap spectrometer (LTQ Orbitrap). Prior acquisition spectrum, background originating from ambient air first transferred C-trap. Ions forming MS or MS(n) spectrum then added this species, all ions...
The function of many the uncharacterized open reading frames discovered by genomic sequencing can be determined at level expressed gene products, proteome. However, identifying cognate from minute amounts protein has been one major problems in molecular biology. Using yeast as an example, we demonstrate here that mass spectrometric identification is a general solution to this problem given completely sequenced genome. As first screen, our strategy uses automated laser desorption ionization...
Cellular processes such as proliferation, differentiation, and adaptation to environmental changes are regulated by protein phosphorylation. Development of sensitive comprehensive analytical methods for determination phosphorylation is therefore a necessity in the pursuit detailed molecular view complex biological processes. We present quantitative modification-specific proteomic approach that combines stable isotope labeling amino acids cell culture (SILAC) quantitation with IMAC...
Electrification of conventionally fired chemical reactors has the potential to reduce CO2 emissions and provide flexible compact heat generation. Here, we describe a disruptive approach fundamental process by integrating an electrically heated catalytic structure directly into steam-methane-reforming (SMR) reactor for hydrogen production. Intimate contact between electric source reaction site drives close thermal equilibrium, increases catalyst utilization, limits unwanted byproduct...
Four groups of catalysts have been tested for hydrodeoxygenation (HDO) phenol as a model compound bio-oil, including oxide catalysts, methanol synthesis reduced noble metal and non-noble catalysts. In total, 23 different were at 100 bar H2 275 °C in batch reactor. The experiments showed that none the oxides or had any significant activity HDO under given conditions, which linked to their inability hydrogenate aromatic ring phenol. over could effectively be described by kinetic involving...
Abstract Background Mass spectrometry has become a powerful tool for the analysis of large numbers proteins in complex samples, enabling much proteomics. Due to various analytical challenges, so far no proteome been sequenced completely. O'Shea, Weissman and co-workers have recently determined copy number yeast proteins, making this an excellent model system study factors affecting coverage. Results To probe depth determine currently preventing complete analysis, we grew cells, extracted...
Mass spectrometry-based proteomics critically depends on algorithms for data interpretation. A current bottleneck in the rapid advance of technology is closed nature and slow development cycle vendor-supplied software solutions. We have created an open source environment, called MSQuant, which allows visualization validation peptide identification results directly raw mass spectrometric data. MSQuant iteratively recalibrates MS thereby significantly increasing accuracy leading to fewer false...
Conference Article| August 01 1996 A strategy for identifying gel-separated proteins in sequence databases by MS alone An. Shevchenko; Shevchenko 1Protein & Peptide Group, EMBL, Meyerhofstrasse 1, 69012 Heidelberg Germany Search other works this author on: This Site PubMed Google Scholar M. Wilm; Wilm O. Vorm; Vorm N. Jensen; Jensen A. V. Podtelejnikov; Podtelejnikov G. Neubauer; Neubauer Al. P. Mortensen; Mortensen Mann Biochem Soc Trans (1996) 24 (3): 893–896....
Abstract The tailored chemical synthesis of binary and ternary alloy nanoparticles with a uniform elemental composition is presented. Their dual use as magnetic susceptors for induction heating catalytic agent steam reforming methane to produce hydrogen at temperatures near above 800 °C demonstrated. performance two chemically synthesized samples CoNi Cu ⊂ are compared held against traditional Ni‐based catalyst. structural, magnetic, properties the were characterized by X‐ray diffraction,...
Electrification of endothermic reactions has the potential to provide a compact and flexible reactor concept, at same time, substantially reduce CO2 emissions relative combustion-heated processes. Here, we show how integrated electrical heating using wash-coated catalytic structure can resolve limiting thermal conductivity across catalyst. The inherent uniform supply heat enables engineering efficiency desired values by changing wash-coat thickness. Overall, approach diminishes as design...
Increasing implementation of renewable energy requires an infrastructure compatible with the intermittent production green electricity. Herein we show flexibility electrically heated steam methane reforming integrated ohmic heating, through a combination CFD modelling and lab scale reactor tests. It is shown how start-up from idle state to operation conditions can be achieved instantaneous application full power required for steady conversion 80%, initial heating rates exceeding 50 °C/min....
Electrification of the traditional steam methane reforming (SMR) technology for syngas manufacturing has a significant CO2 reduction potential and make it more feasible to operate in combination with carbon capture/utilization, especially if renewable electricity is used. This pilot plant study demonstrates first operational experience industrial-scale electrified (eSMR) using biogas as sustainable feedstock. Across an operating envelope spanning from combinations 5 20 barg 750 °C 1000 °C,...
The adipose tissue has important secretory and endocrine functions in humans. regulation of adipocyte differentiation been actively pursued using transcriptomic methods over the last several years. Quantitative proteomics emerged as a promising approach to obtain temporal profiles biological processes such differentiation. Stable isotope labeling with amino acids cell culture (SILAC) is simple robust method for proteins vivo. Here, we describe development application five-plex SILAC...
We demonstrated a proof-of-concept catalytic steam reforming flow reactor system heated only by supported magnetic nickel–cobalt nanoparticles in an oscillating field. The heat transfer was facilitated the hysteresis heating alone. This produced sufficient power input to equilibrate reaction at above 780 °C with more than 98% conversion of methane. high methane indicated that Co-rich Curie temperature provide enable endothermic reaction, activity Ni content nanoparticles. losses obtained...
The long term stability and resistance toward carbon deposition, sulfur, chlorine, potassium of Ni/ZrO2 as a catalyst for the hydrodeoxygenation (HDO) guaiacol in 1-octanol (as model compound system bio-oil) has been investigated at 250 °C 100 bar trickle bed reactor setup. Without impurities feed good could be achieved over more than h operation, particularly sample prepared with small Ni particles, which minimized deposition. Exposing to 0.05 wt% sulfur resulted rapid deactivation complete...