Eeva Kuisma
A5086313624- Viral Infections and Outbreaks Research
- Viral Infections and Vectors
- COVID-19 epidemiological studies
- Disaster Response and Management
- Bacterial Infections and Vaccines
- Zoonotic diseases and public health
- Bacteriophages and microbial interactions
- SARS-CoV-2 and COVID-19 Research
- Hepatitis B Virus Studies
- COVID-19 Clinical Research Studies
- Bat Biology and Ecology Studies
- Pneumonia and Respiratory Infections
- Social Sciences and Governance
- Respiratory viral infections research
- Monoclonal and Polyclonal Antibodies Research
- Complement system in diseases
- French Urban and Social Studies
- Rabies epidemiology and control
- Vaccine Coverage and Hesitancy
- Animal Virus Infections Studies
- Global Security and Public Health
- Mosquito-borne diseases and control
- SARS-CoV-2 detection and testing
- Vibrio bacteria research studies
Wildlife Conservation Society Congo
2019-2023
Wildlife Conservation Society United Kingdom
2022-2023
Wildlife Conservation Society
2019-2021
Public Health England
2015-2019
European Molecular Biology Laboratory
2016-2019
Google (United States)
2019
Bernhard Nocht Institute for Tropical Medicine
2015-2016
Ebola virus disease (EVD) is a highly lethal condition for which no specific treatment has proven efficacy. In September 2014, while the outbreak was at its peak, World Health Organization released short list of drugs suitable EVD research. Favipiravir, an antiviral developed severe influenza, one these. late conditions starting randomized trial were not fulfilled two reasons. One perception that, given high number patients presenting simultaneously and very mortality rate disease, it...
Analysis of 179 new Ebola virus sequences from patient samples collected in Guinea between March 2014 and January 2015 shows how different lineages evolved spread West Africa. Miles Carroll colleagues report describe the genetic evolution circulating Africa, based on 2015. Their analysis Africa Sierra Leone, Liberia. is currently witnessing most extensive (EBOV) outbreak so far recorded1,2,3. Until now, there have been 27,013 reported cases 11,134 deaths. The origin thought to a zoonotic...
By January, 2016, all known transmission chains of the Ebola virus disease (EVD) outbreak in west Africa had been stopped. However, there is concern about persistence reproductive tract men who have survived EVD. We aimed to use biostatistical modelling describe dynamics RNA load seminal fluid, including clearance parameters.In this longitudinal study, we recruited discharged from three treatment units Guinea between January and July, 2015. Participants provided samples fluid at follow-up...
We report 2 cases of Ebola viral disease (EVD) in pregnant women who survived, initially with intact pregnancies. Respectively 31–32 days after negativation the maternal blood EVD-polymerase chain reaction (PCR) both patients delivered a stillborn fetus persistent EVD-PCR amniotic fluid positivity.
Abstract Background In 2015, the laboratory at Ebola treatment center in Coyah, Guinea, confirmed virus disease (EVD) 286 patients. The cycle threshold (Ct) of an virus–specific reverse transcription–polymerase chain reaction assay and 13 blood chemistry parameters were measured on admission during hospitalization. Favipiravir was offered to patients with EVD a compassionate-use basis. Methods To reduce biases raw field data, we carefully selected 163 for retrospective study assess...
Background. A unit of the European Mobile Laboratory (EMLab) consortium was deployed to Ebola virus disease (EVD) treatment in Guéckédou, Guinea, from March 2014 through 2015. Methods. The diagnosed EVD and malaria, using RealStar Filovirus Screen reverse transcription–polymerase chain reaction (RT-PCR) kit a malaria rapid diagnostic test, respectively. Results. cleaned EMLab database comprised 4719 samples 2741 cases suspected Guinea. 1231 2178 hospitalized patients (57%) 281 563 who died...
Ebolavirus (EBOV) has caused disease outbreaks taking thousands of lives, costing billions dollars in control efforts and threatening great ape populations. EBOV ecology is not fully understood but infected wildlife consumption animal carcasses have been linked to human outbreaks, especially the Congo Basin. Partnering with Congolese Ministry Health, we conducted mortality surveillance educational outreach northern Republic (RoC). Designed for detection alert public health authorities,...
With limited data available from Central Africa, the aim of our study was to evaluate anti-SARS-CoV-2 Ab prevalence in indigenous residents Bomassa, a village located Sangha region Republic Congo.Plasma and oropharyngeal swab samples were collected 304 healthy adult individuals, randomly recruited May 2021 before vaccine introduction area. In addition, 82 plasma same area 2019 included as controls for investigation cross-reactivity against other coronaviruses. The SARS-CoV-2 virus detected...
On the 8th of May, 2018, an outbreak Ebola virus disease (EVD) was declared, originating in Bikoro region Democratic Republic Congo (DRC) near border with neighboring (ROC). Frequent trade and migration occur between DRC ROC-based communities residing along River. In June a field team deployed to determine whether Zaire ebolavirus (Ebola (EBOV)) contemporaneously circulating local bats at human-animal interface ROC EVD outbreak. Samples were collected from Cuvette Likouala departments, ROC,...
The correlate of protection for the licensure meningococcal vaccines is serum bactericidal activity. However, evidence indicates that a complex situation and other mechanisms, such as antibody-mediated, complement-dependent opsonophagocytosis (OP), may play role in should be investigated order to understand immunity this disease. In study, high-throughput flow cytometric opsonophagocytic assay (OPA) was optimized. measures presence killed fluorescently labeled Neisseria meningitidis within...
The biology and ecology of Africa’s largest fruit bat remains largely understudied enigmatic despite at least two highly unusual attributes. acoustic lek mating behavior the hammer-headed (Hypsignathus monstrosus) in Congo basin was first described 1970s. More recently molecular testing implicated this species other African bats as potential reservoir hosts for Ebola virus it one only epidemiologically linked to 2008 Luebo, Democratic Republic Congo, outbreak. Here we share findings from...
Early detection of Ebola virus spillover into wildlife is crucial for rapid response. We developed and validated a portable, cold-chain independent RT-qPCR assay.
Background: With limited data available from Central Africa, the aim of our study was to evaluate anti-SARS-CoV-2 Ab prevalence in indigenous residents Bomassa, a village located Sangha region Republic Congo.Methods: Plasma and oropharyngeal swab samples were collected 304 healthy adult individuals, randomly recruited May 2021 before vaccine introduction area.In addition, 82 plasma same area 2019 included as controls for investigation cross-reactivity against other coronaviruses.The...
Purpose: We examine if local communities reporting great ape and other mammal carcasses are able to act as an effective wildlife mortality surveillance network for Ebola virus disease (EVD) with wide-coverage low financial commitment. Methods & Materials: Partnering the Congolese Ministry of Health (MoH), Wildlife Conservation Society (WCS) conducted community outreach campaigns in Cuvette Sangha regions Republic Congo (RoC). As several recorded EVD epidemics have been preceded by epizootics...
Abstract The biology and ecology of Africa’s largest fruit bat remains largely understudied enigmatic despite at least two highly unusual attributes. acoustic lek mating behavior the hammer-headed ( Hypsignathus monstrosus ) in Congo basin was first described 1970s. Then 2000s, molecular testing implicated this species other bats as potential reservoir hosts for Ebola virus it one only epidemiologically linked to 2008 Luebo, Democratic Republic Congo, outbreak. Here we share findings from...