A5056852952- Reproductive Health and Contraception
- Maternal and Perinatal Health Interventions
- Gynecological conditions and treatments
- Maternal Mental Health During Pregnancy and Postpartum
- Reproductive Health and Technologies
- Ectopic Pregnancy Diagnosis and Management
- Global Maternal and Child Health
- Maternal and fetal healthcare
- Pregnancy and preeclampsia studies
- Assisted Reproductive Technology and Twin Pregnancy
- Prenatal Substance Exposure Effects
- Adolescent Sexual and Reproductive Health
- Grief, Bereavement, and Mental Health
- Family Dynamics and Relationships
- Female Genital Mutilation/Cutting Issues
- Preterm Birth and Chorioamnionitis
- Diversity and Career in Medicine
- Uterine Myomas and Treatments
- Cervical Cancer and HPV Research
- Healthcare Policy and Management
- Birth, Development, and Health
- Systemic Lupus Erythematosus Research
- Pregnancy-related medical research
- Reproductive System and Pregnancy
- Endometriosis Research and Treatment
New York Hospital Queens
2024
Presbyterian Hospital
2024
Cornell University
2022-2024
NewYork–Presbyterian Hospital
2024
Yale University
2013-2023
Weill Cornell Medicine
2022
American Congress of Obstetricians and Gynecologists
2022
Patient-Centered Outcomes Research Institute
2022
Society of Family Planning
2022
University of California, San Francisco
2022
BACKGROUND. The effects of the novel coronavirus disease 2019 (COVID-19) in pregnancy remain relatively unknown. We present a case second trimester with symptomatic COVID-19 complicated by severe preeclampsia and placental abruption.
Abstract Background The effects of Covid-19 in pregnancy remain relatively unknown. We present a case second trimester with symptomatic complicated by severe preeclampsia and placental abruption. Methods analyzed placenta for the presence SARS-CoV-2 through molecular immunohistochemical assays electron microscopy, we measured maternal antibody response blood to this infection. Results localized predominantly syncytiotrophoblast cells at maternal-fetal interface placenta. Histological...
Essure, a female-sterilization device, is being reevaluated by an FDA panel 13 years after its original approval. Would concerns about safety and effectiveness have been addressed earlier with better research result dissemination?
Childbirth is the leading cause of hospital admission in United States, yet there has been little research on variation costs associated with childbirth. Using data from 2011 Nationwide Inpatient Sample, we characterized estimated facility hospitalizations for low-risk childbirth across US hospitals. We found that average cost per maternity stay ranged $1,189 to $11,986 (median: $4,215), a 2.2-fold difference between 10th and 90th percentiles. Estimated were higher at hospitals rates...
Obstet Gynecol Surv 2016;71(2):86–87 In 2002, a novel nonsurgical birth control implant, the Essure system, was fast tracked for Food and Drug Administration (FDA) approval. At that time, has remained only permanent option women other than tubal litigation, major surgical procedure.
Abstract Background Tubal ligation remains common in the USA, especially among low-income patients. Objective To compare effectiveness and safety of intrauterine contraceptives (IUC) to laparoscopic tubal for Medicaid clients. Design We partnered with patient clinician stakeholders conduct a retrospective cohort study using California claims patients who had an IUC placed or performed 2008–2014, excluding procedures within 42 days birth. applied log-linear (Poisson) event-history regression...
In Brief OBJECTIVE: To evaluate the cost-effectiveness of immediate compared with delayed (6 weeks) postpartum etonogestrel implant insertion in preventing future unintended pregnancy. METHODS: We constructed a decision-analytic model to examine hypothetical population women who request contraceptive after giving birth. The timeframe for analysis was from time childbirth 1 year postpartum. Model inputs were derived comprehensive literature review. (before discharge hospital stay) (at first...
BackgroundTubal sterilization is the most commonly used method of contraception in United States. Because contraceptive effectiveness influences selection, we examined typical use failure rates after tubal States.MethodsWe estimated pregnancy using data from four waves National Survey Family Growth (NSFG), representative samples U.S. women aged 15 to 44 years, collected 2002, 2006 2010, 2011 2013, and 2013 2015. weighting was survival analysis examine time first sterilization. Data these...
Objective: Unplanned and poorly timed pregnancies are associated with adverse maternal neonatal outcomes. Further understanding of preconception substance use unplanned pregnancy is warranted. Methods: Data were analyzed from a prospective study enrolling women early in pregnancy. Preconception tobacco, alcohol, marijuana, opioid, cocaine was ascertained. Participants reported whether their current planned it good time to be pregnant. Multivariable logistic regression modeling generated risk...
In Brief OBJECTIVE: To estimate the probability of successful sterilization after an hysteroscopic or laparoscopic procedure. METHODS: An evidence-based clinical decision analysis using a Markov model was performed to procedure sterilization, in operating room, and office. Procedure follow-up testing probabilities for were estimated from published sources. RESULTS: base case analysis, proportion women having on first attempt is 99% 88% 87% The within 1 year with 95% 94% These estimates...
Problem There is a strong correlation between intrauterine bacterial infection and preterm labor. While inflammation common mechanism, certain pathogens may trigger placental apoptosis. TLR 2 activation by gram‐positive peptidoglycan ( PDG ) induces first‐trimester trophoblast apoptosis decreased IL ‐6 secretion. This dependent upon the presence of 1 absence 6 both coreceptors. As 10 also coreceptor, objective this study was to determine its expression function in trophoblast. Method...
What is the effect of pravastatin on antiphospholipid antibody (aPL) modulation human first trimester trophoblast function? Pravastatin does not prevent effects aPL cell function. Antiphospholipid syndrome (APS) associated with recurrent pregnancy loss and late complications, such as pre-eclampsia, owing to direct targeting placenta by aPL. While treatment heparin reduces rate loss, risk for severe pre-eclampsia remains high. Thus, there a need find alternative treatments prenatal management...
Problem Women with antiphospholipid syndrome ( APS ) are at increased risk of recurrent pregnancy loss RPL and preeclampsia. Antiphospholipid antibodies (a PL directly alter trophoblast function. Treatment low molecular weight heparin LMWH reduces the but not Moreover, stimulates sF lt‐1 release, an anti‐angiogenic factor associated Since vitamin D deficiency is preeclampsia, this study sought to determine effect on function in setting a . Method A human first trimester cell line HTR 8)...