Ulcerative colitis (UC) is a recurrent inflammatory bowel disease (IBD) that causes long-lasting inflammation on the innermost lining of colon and rectum. Leaf decoctions Cordia vignei have been used in traditional medicine either alone or combination with other plant preparations to treat disease.In this study, we investigated effect hydroethanolic extract disease.Male Sprague Dawley rats received oral treatment saline (10 ml/kg), sulfasalazine (500 mg/kg), CVE (30-300 mg/kg) daily for 7...

<b>Objectives:</b> Various parts of <i>Trichilia monadelpha</i> (Thonn) JJ De Wilde (Fam. Meliaceae) are used in Ghanaian traditional medicine for the treatment painful and inflammatory conditions. The present study examined analgesic properties petroleum ether (PEE), ethyl acetate (EAE), hydro-ethanolic (HAE) extract stem bark plant murine models.<br><b>Materials Methods:</b> PEE, EAE, HAE were assessed chemical (acetic acid-induced abdominal writhing formalin tests), thermal (hot plate...

Solanum mauriatianum is a woody plant that grows naturally in the tropical and temperate regions. In most rural communities Ghana other parts of West Africa, it widely used for treatment ailments such as hemorrhoid, yaws, ulcers, wounds. Despite long-term usage traditional medicine, there no scientific report on its efficacy. Objective: This study investigates wound healing properties ethanolic extract plant. Method: The leaf was formulated into aqueous cream (SME) at concentrations 2.5%,...

Knowledge of the floristic composition, structure and conservation status tropical forests is essential for their sustainable management conservation, although this remains poorly documented in some countries. Here, we investigated plant species diversity, distribution Ankasa Resource Reserve, Ghana, to inform efforts. A total 150 plots (20 m × 20 each) were demarcated across six recognizable sites, namely; Lophira Tree (LT), Bucket Trail (BT), Big Area (BGA), Bamboo Cathedral (BC), Elubo...

Journal of Pharmaceutical Research International (ISSN: 2456-9119) is dedicated to publish high quality papers in all areas pharmaceutical Science including drugs, community pharmacy, hospital clinical compounding consultant internet veterinary nuclear military pharmacy informatics, pharmaceutics, medicinal chemistry, pharmacognosy, pharmacotherapy, pharmacodynamics, pharmacokinetics, pharmacology, neuropharmacology, psychopharmacology, pharmacogenetics, pharmacogenomics,...

In recent times, climate change has generated a global issue of discourse, because its potential effects on the human interest, including agriculture. It is observed that absence rapid response strategies to both short and long term change, variability will have significant effect agricultural production. Climate serious concern Nigeria production food security. This paper discussed general components impact their possible The recommended development reporting national inventories green...

Journal of Pharmaceutical Research International (ISSN: 2456-9119) is dedicated to publish high quality papers in all areas pharmaceutical Science including drugs, community pharmacy, hospital clinical compounding consultant internet veterinary nuclear military pharmacy informatics, pharmaceutics, medicinal chemistry, pharmacognosy, pharmacotherapy, pharmacodynamics, pharmacokinetics, pharmacology, neuropharmacology, psychopharmacology, pharmacogenetics, pharmacogenomics,...

Background: Lannea microcarpa Engl. and K. Krause (Family Anacardiaceae), a tropical tree is used traditionally in Africa for both medicinal non-medicinal purposes. Folkoric uses of the plant include wound healing, conjunctivitis, stomatitis gingivitis among others. Inflammatory reactions are involved several diseases which this to manage. This study was therefore aimed at investigating antiinflammatory effects aqueous extract microcapa.Methods: Oedema induced right hind paws Sprague Dawley...

Background: Trichilia monadelpha is used either alone or in combination with other plants to treat many diseases West Africa. Earlier, the anti-inflammatory, analgesic and anti-parasitic effects of plant have been investigated confirm its folkloric use. The current study aimed at investigating sub-acute toxicity profile as well hypno-sedative effect aqueous extract (TAE).Methods: For pentobarbitone-induced sleeping test, rats (150-200 g, n=5) were pre-treated TAE (100, 300 1000 mg/kg, p.o.)...

Background: Chronic allergic lung diseases, such as asthma, are often marked by increased systemic inflammatory responses and cachexia co-morbidities. Objectives:The study aimed at evaluating the anti-inflammatory anti-cachectic properties of a hydro-ethanolic extract Scoparia dulcis (SDE) in an ovalbumin-induced

<b>Abstract ID 90351</b> <b>Poster Board 077</b> <b>Background:</b> Ulcerative colitis is a chronic debilitating inflammatory disease that affects the colon and rectum typically involves innermost lining or mucosal membrane. Due to unwanted effects of synthetic anti-colitis drugs, natural products are being explored as alternative complementary therapy. Aim: This study investigates anti-ulcerative hydroethanolic root extract <i>Ficus capensis</i> (FCE) in Sprague Dawley rats. Methods: Male...

Inflammatory responses, including airway inflammation, hyper-responsiveness, mucus hyper-secretion, prostaglandins and Th2 cytokines infiltration in the submucosa, frequently occur allergic respiratory disorders. This study sought to investigate effects of hydro-ethanolic extract Scoparia dulcis (SDE) on goblet cell hyperplasia, hypersecretion, prostaglandin (PG)-D2 using murine asthma models. Allergic was induced healthy guinea-pigs, mice, by exposing them ovalbumin (OVA) sensitization...

Uropathogens are microorganisms that cause urinary tract infections (UTIs). Owing to higher blood glucose levels and compromised immune functions, treatment of uropathogens in diabetic patients is a challenge.

Cordia vignei Hutch and Dalziel (Fam. Boraginaceae) is a woody plant found in west tropical Africa. The aim of this research to find out if the leaf extract prevents oedema animal models.(a) Inflammation was induced animals by injecting 100 µl 2% lambda carrageenan into subplantar tissue right footpads 7-day-old chicks 1 h before or after oral administration 30-300 mgkg-1 CVE. Oedema measured for 5 using water displacement method. (b) ICR mice injection prostaglandin E2 (PGE2) (50 nM) 30...

The study assessed the technical performance of three alternative drying systems for maize by smallholder farmers in Ghana. dryers considered were AflaStop (EasyDry M500) dryer, STR Column and Solar Bubble dryer. Analytical Hierarchy Process (AHP) was used comparative analysis selection best system based on its performance, durability, ease use, cost manufacture operational cost. rate efficiency determined AflaStop, Column, dryer 2.20 %/h, 1.90 0.98 %/h 81.07 %, 64.65 36.17 respectively....