A5075276643- Phytochemistry and Biological Activities
- Natural product bioactivities and synthesis
- Cholesterol and Lipid Metabolism
- Eicosanoids and Hypertension Pharmacology
- Phytochemistry and Bioactive Compounds
- Ethnobotanical and Medicinal Plants Studies
- Essential Oils and Antimicrobial Activity
- Inflammatory mediators and NSAID effects
- Phytochemical compounds biological activities
- Psoriasis: Treatment and Pathogenesis
- Polysaccharides and Plant Cell Walls
- Pharmacological Effects of Medicinal Plants
- Pharmacological Effects of Natural Compounds
- Mangiferin and Mango Extracts
- Hibiscus Plant Research Studies
- Phytochemistry and biological activities of Ficus species
- Diverse Scientific Research Studies
- Adipokines, Inflammation, and Metabolic Diseases
- Ziziphus Jujuba Studies and Applications
- Natural Antidiabetic Agents Studies
- Ginger and Zingiberaceae research
University of Cape Coast
2017-2024
Kwame Nkrumah University of Science and Technology
2016
University for Development Studies
2016
Cordia vignei plant is used in folkloric medicine to treat numerous inflammatory disorders. The bowel disease incidence rate steadily increasing developing countries and mostly characterized by recurrent inflammation along with major problems. current study aimed establish the acute oral safety of leaf extract evaluated its antiulcerogenic activities a DSS-induced colitis model mice. phytomedicinal efficacy CVE (30, 100, 300 mg/kg, p.o) on was assessed inducing 5% () dextran sodium sulfate...
Objective: To assess the effect of leaf extract Persicaria lanigera on cotton pellet-induced granuloma tissue formation and acetic acid-induced ulcerative colitis. Methods: Rats were randomly divided into six groups: normal control, negative positive control (dexamethasone or sulfasalazine) as well (100-600 mg/kg)-treated groups. The effects extracts body weight, antioxidant, hematological parameters, mast cell proliferation, assessed. In addition, a histological evaluation was conducted....
Background: Lannea microcarpa Engl. and K. Krause (Family Anacardiaceae), a tropical tree is used traditionally in Africa for both medicinal non-medicinal purposes. Folkoric uses of the plant include wound healing, conjunctivitis, stomatitis gingivitis among others. Inflammatory reactions are involved several diseases which this to manage. This study was therefore aimed at investigating antiinflammatory effects aqueous extract microcapa.Methods: Oedema induced right hind paws Sprague Dawley...
Plant species have been used traditionally to treat numerous inflammatory disorders because of their known medicinal properties. This study aimed assess the anti-inflammatory effect aqueous ethanolic leaf extract Persicaria lanigera using acute models. The safety profile was assessed an toxicity model. (100-600 mg·kg-1, p.o.) studied in carrageenan-induced paw oedema, zymosan-induced knee joint arthritis, and histamine-induced oedema Sprague-Dawley rats (n = 5). It observed that administered...
Background: Trichilia monadelpha is used either alone or in combination with other plants to treat many diseases West Africa. Earlier, the anti-inflammatory, analgesic and anti-parasitic effects of plant have been investigated confirm its folkloric use. The current study aimed at investigating sub-acute toxicity profile as well hypno-sedative effect aqueous extract (TAE).Methods: For pentobarbitone-induced sleeping test, rats (150-200 g, n=5) were pre-treated TAE (100, 300 1000 mg/kg, p.o.)...
Abstract Objectives Ziziphus abyssinica (ZA) is employed in managing several ailments Traditional African Medicine. Scientific evaluations are necessary to ascertain the medicinal potential of ZA as a source new drug molecules. This study investigated possible therapeutic benefit leaf (ZAL) and root bark (ZARB) extracts an experimental model multi-organ injuries induced by phenylhydrazine (PHZ). Methods Hyperbilirubinaemia, hepatotoxicity, nephrotoxicity splenic were pretreating albino rats...
Bombax costatum (Bombacaceae) is traditionally used as a decoction of the leaves, stem, and root to treat headaches, fever, oedema that may be associated with inflammatory conditions. Thus, aim this study was evaluate effect 70%v/v ethanolic extract stem bark on acute chronic inflammation. The (10, 50, 100 mg kg-1, p.o) studied in prostaglandin E2-induced paw Sprague-Dawley rats (n = 5). Subsequently, clonidine haloperidol-induced catalepsy also investigated ICR mice Finally, ability inhibit...
Hyperlipidaemia is a major risk factor for cardiovascular diseases, the leading cause of death globally. Celecoxib attenuated hypercholesterolaemia associated with CCl 4 -induced hepatic injury in rats without improving liver function our previous study. This present study investigated lipid lowering potential celecoxib normal fed coconut oil subjected to five deep-frying episodes. Male Sprague Dawley were randomly assigned groups (n = 6 rats/group) which received physiological saline (10...
Knowledge, Attitude and Practice of Malaysian Public University Students on Risk Factors for Cardiovascular DiseasesMardhiah Mahada Ibrahim, Nor Azlina A. Rahman, Iza Mainul Haque
Abstract Hyperlipidaemia is a major risk factor for cardiovascular diseases, the leading cause of death globally. Celecoxib attenuated hypercholesterolemia associated with CCl 4 -induced hepatic injury in rats without improving liver function our previous study. This present study investigated lipid lowering potential celecoxib normal fed coconut oil subjected to five deep-frying episodes. Male Sprague Dawley were randomly assigned groups (n=6 rats/group) which received physiological saline...