- Supramolecular Self-Assembly in Materials
- Surface Chemistry and Catalysis
- Lipid Membrane Structure and Behavior
- Cancer-related gene regulation
- Lanthanide and Transition Metal Complexes
- Radioactive element chemistry and processing
- Advanced Polymer Synthesis and Characterization
- Peptidase Inhibition and Analysis
- Synthesis and Properties of Aromatic Compounds
- X-ray Diffraction in Crystallography
- Zeolite Catalysis and Synthesis
- Luminescence and Fluorescent Materials
- Mitochondrial Function and Pathology
- Catalysis and Oxidation Reactions
- Metabolomics and Mass Spectrometry Studies
- Crystallization and Solubility Studies
- Bioinformatics and Genomic Networks
- Ubiquitin and proteasome pathways
- Catalytic Processes in Materials Science
Beijing National Laboratory for Molecular Sciences
2023-2024
Chinese Academy of Sciences
2002-2024
Institute of Chemistry
2023-2024
University of Chinese Academy of Sciences
2023
Peking University
2016-2021
University of Tennessee at Knoxville
2016
Dalian Institute of Chemical Physics
2002
The need to secure future supplies of energy attracts researchers in several countries a vast resource nuclear fuel: uranium seawater (estimated at 4.5 billion tons seawater). In this study, we developed effective adsorbent fibers for the recovery from via atom-transfer radical polymerization (ATRP) poly(vinyl chloride)-co-chlorinated chloride) (PVC-co-CPVC) fiber. ATRP was employed surface graft acrylonitrile (AN) and tert-butyl acrylate (tBA), precursors uranium-interacting functional...
Abstract The phase evolution of zirconia (ZrO 2 ), sulfated (SO 4 2− /ZrO ) and yttrium oxide incorporated (Y O 3 –ZrO from the tetrahedral to monoclinic was studied using UV Raman spectroscopy, visible spectroscopy x‐ray diffraction (XRD). It is clearly observed that there are discrepancies between results spectra, spectra XRD patterns. change tetragonal always earlier or at lower calcination temperatures as by than XRD. found be more sensitive surface region while supply information mainly...
Abstract N-terminal acetylation (Nt-acetylation), carried out by acetyltransferases (NATs), is a conserved and primary modification of nascent peptide chains. Naa60 (also named NatF) recently identified NAT found only in multicellular eukaryotes. This protein was shown to locate on the Golgi apparatus mainly catalyze Nt-acetylation transmembrane proteins, it also harbors lysine N ε -acetyltransferase (KAT) activity ε-amine. Here, we report crystal structures human (hNaa60) complex with...
Abstract Here we designed enantiomeric lipid‐mimetic glutamic acid derivatives ( L/D ‐UG) and investigated their self‐assembled chiral nanostructures’ interaction with the protein adsorption as well osteogenesis. It was found that L or D ‐UG molecules can self‐assemble into vesicle bilayers two‐dimensional (2D) nanocrystals via a kinetic thermodynamic control, respectively. These vesicles 2D crystals showed differentiated of proteins, determined by curvature chirality. Specifically,...
Abstract Chiroptical inversion of amyloid fibrils is a novel phenomenon and fundamental importance; however, the underlying structural basis remains poorly understood. Here, co‐assembly Thioflavin T (ThT) with T1 fibril induced supramolecular chirality investigated by circular dichroism (ICD) circularly polarized luminescence (CPL), followed direct morphological helicity observation an atomic force microscope (AFM). ThT exhibits negative ICD CPL when assembled on left‐handed fibril....
Abstract Here we designed enantiomeric lipid‐mimetic glutamic acid derivatives ( L/D ‐UG) and investigated their self‐assembled chiral nanostructures’ interaction with the protein adsorption as well osteogenesis. It was found that L or D ‐UG molecules can self‐assemble into vesicle bilayers two‐dimensional (2D) nanocrystals via a kinetic thermodynamic control, respectively. These vesicles 2D crystals showed differentiated of proteins, determined by curvature chirality. Specifically,...
Abstract Chirality‐directed stem‐cell‐fate determination involves coordinated transcriptional and metabolomics programming that is only partially understood. Here, using high‐throughput transcriptional‐metabolic profiling pipeline network analysis, the molecular architecture of chirality‐guided mesenchymal stem cell lineage diversification revealed. A total 4769 genes 250 metabolites are identified significantly biased by biomimetic chiral extracellular microenvironment (ECM)....