A5044825834- Advanced MRI Techniques and Applications
- EEG and Brain-Computer Interfaces
- Functional Brain Connectivity Studies
- Neural dynamics and brain function
- Electrical and Bioimpedance Tomography
- Neuroscience and Neural Engineering
- Atomic and Subatomic Physics Research
- Blind Source Separation Techniques
- Transcranial Magnetic Stimulation Studies
- Non-Destructive Testing Techniques
- Heart Rate Variability and Autonomic Control
- Characterization and Applications of Magnetic Nanoparticles
- Neonatal and fetal brain pathology
- Cardiac electrophysiology and arrhythmias
- ECG Monitoring and Analysis
- Advanced Neuroimaging Techniques and Applications
- Electromagnetic Fields and Biological Effects
- Muscle activation and electromyography studies
- Glaucoma and retinal disorders
- Numerical methods in inverse problems
- Visual perception and processing mechanisms
- Neural Networks and Applications
- Sparse and Compressive Sensing Techniques
- Neuroscience and Music Perception
- Ocular and Laser Science Research
Technische Universität Ilmenau
2016-2025
Jena University Hospital
2015-2025
Max Planck Institute for Human Cognitive and Brain Sciences
2017-2021
Kirchhoff (Germany)
2006-2020
Friedrich Schiller University Jena
2007-2018
University of Information Technology and Management in Rzeszow
2018
Information Technology University
2014
FH Aachen
2013
Walter de Gruyter (Germany)
2013
Karlsruhe Institute of Technology
2013
Pianists often report that pure listening to a well-trained piece of music can involuntarily trigger the respective finger movements. We designed magnetoencephalography (MEG) experiment compare motor activation in pianists and nonpianists while piano pieces. For pianists, we found statistically significant increase activity above region contralateral cortex. Brain surface current density (BSCD) reconstructions revealed spatial dissociation this between notes preferably played by thumb little...
Modeling in magnetoencephalography (MEG) and electroencephalography (EEG) requires knowledge of the vivo tissue resistivities head. The aim this paper is to examine influence resistivity changes on neuromagnetic field electric scalp potential. A high-resolution finite element method (FEM) model (452162 elements, 2-mm resolution) human head with 13 different types employed for purpose. Our main finding was that magnetic fields are sensitive vicinity source. In comparison, surface potentials...
Transcranial direct current stimulation (tDCS) is a noninvasive technique for affecting brain dynamics with promising application in the clinical therapy of neurological and psychiatric disorders such as Parkinson's disease, Alzheimer's depression, schizophrenia. Resting state increasingly play role assessment connectivity-based pathologies We systematically applied tDCS large-scale network model 74 cerebral areas, investigating spatiotemporal changes dynamic states function structural...
Stimulation with rhythmic light flicker (photic driving) plays an important role in the diagnosis of schizophrenia, mood disorder, migraine, and epilepsy. In particular, adjustment spontaneous brain rhythms to stimulus frequency (entrainment) is used assess functional flexibility brain. We aim gain deeper understanding mechanisms underlying this technique predict effects intensity. For purpose, a modified Jansen Rit neural mass model (NMM) cortical circuit used. This mean field has been...
We investigated two important means for improving source reconstruction in presurgical epilepsy diagnosis. The first investigation is about the optimal choice of number epileptic spikes averaging to (1) sufficiently reduce noise bias an accurate determination center gravity activity and (2) still get estimation extent irritative zone. second study focuses on differences single modality EEG (80-electrodes) or MEG (275-gradiometers) especially benefits combined EEG/MEG (EMEG) analysis. Both...
Transcranial direct current stimulation (tDCS), a neuromodulatory non-invasive brain technique, has shown promising results in basic and clinical studies. The known interindividual variability of the effects, however, limits efficacy technique. Recently we reported neurophysiological effects tDCS applied over primary motor cortex at group level, based on data from twenty-nine participants who received 15min either sham, 0.5, 1.0, 1.5 or 2.0 mA anodal, cathodal tDCS. were evaluated via...
Abstract Background The structure of the anatomical surfaces, e.g., CSF and gray white matter, could severely influence flow volume currents in a head model. This, turn, will also scalp potentials inverse source localizations. This was examined detail with four different human models. Methods Four finite element models constructed from segmented MR images an adult male subject were used for this study. These were: (1) Model 1: full model eleven tissues that included detailed scalp, hard soft...
The current dipole is a widely used source model in forward and inverse electroencephalography magnetoencephalography applications. Analytic solutions to the governing field equations have been developed for several approximations of human head using ideal dipoles as model. Numeric approaches such finite-element finite-difference methods become popular because they allow use anatomically realistic models increased computational power that require has readily available. Although numeric can...
Abstract Neither music nor spoken language form uniform auditory streams, rather, they are structured into phrases. For the perception of such structures, detection phrase boundaries is crucial. We discovered electroencephalography (EEG) and magnetoencephalography (MEG) correlates for in music. In EEG, this process was marked by a positive wave approximately between 500 600 ms after offset boundary with centroparietal maximum. MEG, we found major activity an even broader time window (400–700...
Ventricular tachycardia (VT) provoking sudden cardiac death (SCD) are a major cause of mortality in the developed countries. The most efficient therapy for SCD prevention implantable cardioverter defibrillators (ICD). In this study heart rate variability (HRV) measures were analyzed short-term forecasting VT order to improve sensing and enable patient warning forth-coming shocks.The last 1000 normal beat-to-beat intervals before 50 episodes stored by ICD compared individually acquired...
The time-resolved autofluorescence of the eye is used for detection metabolic alteration in diabetic patients who have no signs retinopathy. One from 37 phakic and 11 pseudophakic with type 2 diabetes, one 25 23 healthy subjects were included study. After a three-exponential fit decay autofluorescence, histograms lifetimes τi, amplitudes αi, relative contributions Qi statistically compared between corresponding groups two spectral channels (490<ch1<560 nm, 560<ch2<700 nm). change single...
In state-of-the-art electroencephalography (EEG) Silver/Silver-Chloride electrodes are applied together with electrolyte gels or pastes. Their application requires extensive preparation, trained medical staff and limits measurement time mobility. We recently proposed a novel multichannel cap system for dry EEG mobile out-of-the-lab acquisition. During the tests these polymer-based multipin electrodes, we observed that quality of recording depends on normal force resulting contact pressure....
Novel state-of-the-art amplifier and cap systems enable Electroencephalography (EEG) recording outside of stationary lab during physical exercise body motion. However, extensive preparation time, cleaning, limited long-term stability conventional gel-based electrode pose significant limitations in out-of-the-lab conditions. Dry may contribute to rapid repetitive mobile EEG acquisition with significantly reduced cleaning requirements, possible self-application by the volunteer but are known...
Abstract High‐density electroencephalography (HD‐EEG) is currently limited to laboratory environments since state‐of‐the‐art electrode caps require skilled staff and extensive preparation. We propose evaluate a 256‐channel cap with dry multipin electrodes for HD‐EEG. describe the designs of made from polyurethane coated Ag/AgCl. compare in study 30 volunteers novel HD‐EEG conventional gel‐based electrode‐skin impedances, resting state EEG, visual evoked potentials (VEP). perform wearing...
The aim of this study was to investigate the hypothesis that fetal beat-to-beat heart rate variability (fHRV) displays different time scales sympatho-vagal development prior and after 32 weeks gestation (wks GA). Ninety-two magnetocardiograms singletons with normal courses pregnancy between 24 + 1 41 6 wks GA were studied. Heart patterns either quiet/non-accelerative (fHRP I) or active/accelerative II) recording quality sufficient for fHRV. sample divided into groups <32 GA/>32 GA. Linear...