Fang Huang

ORCID: 0000-0003-3883-0520
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About
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Research Areas
  • Immune cells in cancer
  • Atherosclerosis and Cardiovascular Diseases
  • Psoriasis: Treatment and Pathogenesis
  • Ferroptosis and cancer prognosis
  • Food Chemistry and Fat Analysis
  • Neuroinflammation and Neurodegeneration Mechanisms
  • GDF15 and Related Biomarkers
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Dermatology and Skin Diseases
  • Microbial Metabolism and Applications
  • Genetics, Aging, and Longevity in Model Organisms
  • interferon and immune responses
  • Nutritional Studies and Diet
  • Muscle Physiology and Disorders
  • Glioma Diagnosis and Treatment
  • Extracellular vesicles in disease
  • Diabetic Foot Ulcer Assessment and Management
  • Head and Neck Cancer Studies
  • Wound Healing and Treatments
  • Cancer-related molecular mechanisms research
  • Immune Response and Inflammation
  • Nutrition, Genetics, and Disease
  • Salivary Gland Tumors Diagnosis and Treatment
  • Proteins in Food Systems
  • Vitamin D Research Studies

Central South University
2023-2024

Zhuhai People's Hospital
2022-2024

Jinan University
2022-2024

Central South University of Forestry and Technology
2023-2024

Union Hospital
2024

Huazhong University of Science and Technology
2024

Abstract Reciprocal interactions between the tumor microenvironment (TME) and cancer cells play important roles in tumorigenesis progression of glioma. Glioma-associated macrophages (GAMs), either peripheral origin or representing brain-intrinsic microglia, are majority population infiltrating immune GAMs, usually classified into M1 M2 phenotypes, have remarkable plasticity regulate through different metabolic pathways. Recently, research efforts increasingly focused on GAMs metabolism as...

10.1186/s13578-024-01231-7 article EN cc-by Cell & Bioscience 2024-04-17

Diabetic foot ulcer (DFU) is a break in the skin of caused by diabetes. It one most serious and debilitating complications The previous study suggested that dominant M1 polarization during DFU could be leading reason behind impaired wound healing. This concluded macrophage predominates tissue. iNOS was increased HG-induced M1-polarized macrophages; conversely, Arg-1 decreased. Macrophage pellets after HG stimulation can impair endothelial cell (EC) function inhibiting viability, tube...

10.3389/fimmu.2023.1104890 article EN cc-by Frontiers in Immunology 2023-05-23

Psoriasis is a systemic inflammatory disease, and the mechanism that links psoriasis to depression still elusive. Hence, this study aimed elucidate potential pathogenesis of comorbidity.The gene expression profiles (GSE34248, GSE78097 GSE161683) (GSE39653) were downloaded from Gene Expression Omnibus (GEO) DataSets. Functional annotation, protein-protein interaction (PPI) network module construction, hub identification co-expression analysis performed, following common differentially...

10.2147/ccid.s413887 article EN cc-by-nc Clinical Cosmetic and Investigational Dermatology 2023-05-01

The polarization of macrophages plays a crucial regulatory role in range physiological and pathological processes involving macrophages. There are numerous concerns with macrophage atherosclerosis; however, most focus on modulating to improve the microenvironment, mechanism action remains unknown. In recent years, advantages natural low-toxicity side effects food medicine homology-derived substances have been widely explored. Few reports started from ingredients homology regulate so that...

10.1021/acs.jafc.3c06375 article EN Journal of Agricultural and Food Chemistry 2023-12-18

Multiple sclerosis (MS) is a common autoimmunity disease of the central nervous system (CNS) that mostly happens in young adults. The chronic clinical features MS include inflammatory demyelination, infiltration immune cells, and secretion cytokines, which have been proved to be associated with CD4+ T cells. Ferroptosis newly discovered programmed cell death mediated by massive lipid peroxidation more sensitive However, effect ferroptosis cells on occurrence progression retains unclear....

10.1016/j.bbrc.2022.12.034 article EN cc-by-nc-nd Biochemical and Biophysical Research Communications 2022-12-17

Background. The objective of this study is to determine the prognostic factors keratinizing squamous cell carcinoma tongue (KTSCC) and establish a nomogram KTSCC assist clinical diagnosis treatment. Methods. This identified 3874 patients with from Surveillance, Epidemiology, End Results (SEER) database, these were randomly divided into training (70%, (n = 2711) validation (30%, n 1163) cohorts. Cox regression was then used filter variables. Nomograms constructed based on meaningful Finally,...

10.1155/2023/3016994 article EN cc-by International Journal of Clinical Practice 2023-02-24

<strong>Background and aims:</strong> Dexamethasone is a common glucocorticoid medication with adverse effects that can cause muscle atrophy, but no drug intervention has been approved or recommended for this condition. KF-8 rice bran-derived anti-oxidant peptide extends the life span of <em>Caenorhabditis elegans</em>. <strong>Methods</strong>: We established <em>C. elegans</em> model dexamethasone-induced myopathy to evaluate potential therapeutic in model.<em> C. function was assessed...

10.26599/fshw.2024.9250132 article EN cc-by-nc-nd Deleted Journal 2024-06-01
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