Gamma titanium-aluminum intermetallic compounds (γ-TiAl) have gained considerable attentions in the aerospace industry due to their exceptional thermal resilience and comprehensive attributes, making them a prime example of lightweight advanced materials. To address frequent occurrence burns severe tool deterioration during process high-efficiency deep grinding (HEDG) on γ-TiAl alloys, ultrasonic vibration-assisted (UVHEDG) has been emerged. Results indicate that UVHEDG, temperature is...

Gypenoside XVII (GP‑17), one of the dominant active components <em>Gynostemma pentaphyllum</em>, has been studied extensively and found to have a variety pharmacological effects, including neuroprotective properties. However, effects GP‑17 against spinal cord injury (SCI), as well its underlying mechanisms action remain unknown. The present study aimed investigate on motor recovery histopathological changes following SCI elucidate in mouse model SCI. Motor was evaluated using Basso, Beattie...

Abstract This paper evaluates the reliability of laser ball soldering under different materials (silicon, ceramics, PCB), solders (lead-free SAC305, leaded SnPb6337), and various sizes solder balls (200, 350, 450 μm) through application design experiment method. The welding process parameters are systematically optimized by coplanarity, shear strength, intermetallic compound alloy layer thickness. We obtained a large amount reference experimental data confirmed innovation practicality...

The present study explored the ways to prepare thickened liquids of different consistencies using lotus root starch (LRS) powder and evaluated their efficacy in treating post-stroke dysphagic patients. Thickened matching four consistency levels advocated by International Dysphagia Diet Standardization Initiative (IDDSI) guidelines were prepared. To assess clinical applicability, 76 patients randomly divided into three groups: a xanthan gum (XG) group (n=26), an LRS control (n=24). All groups...

The tumor microenvironment (TME) has an essential role in tumorigenesis, progression, and therapeutic response many cancers. Currently, the of TME acute myeloid leukemia (AML) is unclear. This study investigated correlation between immune-related genes prognosis AML patients.Transcriptome RNA-Seq data for 151 samples were downloaded from TCGA database (https://portal.gdc.cancer.gov/), immune related (irgs) selected Immport database. Bioinformatics screening was used to identify irgs AML,...

Purpose The transistor circuit based on Moore's Law is approaching the performance limit. three-dimensional integrated (3-D IC) an important way to implement More than Moore. main problems in development of 3-D IC are Joule heating and stress. stresses strains generated ICs will affect electronic products, leading various reliability issues. intermetallic compound (IMC) joint materials structures factors affecting purpose this paper optimize design IC. Design/methodology/approach To IC,...

Aquaporins (AQPs) have been found to be associated with a number of diseases. However, the role AQP‑1 in pathogenesis osteoarthritis remains unclear. We previously that expression was upregulated osteoarthritic cartilage and strongly correlated caspase‑3 activity. The aim this study further investigate association chondrocyte apoptosis rat model osteoarthritis, using RNA interference knock down AQP‑1. For purspose, 72 male Sprague‑Dawley rats were randomly assigned 3 groups as follows:...

Almost 50% of esophageal adenocarcinoma (EAC) patients progressed from Barrett's esophagus (BE). EAC is often diagnosed at late stages and related to dismal prognosis. However, there are still no effective methods for stratification therapy in BE EAC. Two public datasets (GSE26886 GSE37200) were analyzed identify differentially expressed genes (DEGs) between Then, a series bioinformatics analyses performed explore potential biomarkers associated with BE-EAC. 27 up- 104 down-regulated...

&lt;b&gt;&lt;i&gt;Introduction:&lt;/i&gt;&lt;/b&gt; Consistency of liquid food plays an important role in managing patients with dysphagia, which can be objectively evaluated by using International Dysphagia Diet Standardisation Initiative (IDDSI) Flow Test and consistometry. The present study established the relationship between IDDSI consistometric measures examined measurement limitations each test associated thickened liquids prepared starch-based xanthan gum-based thickening agents....

Femoral head necrosis (FHN) is a clinically progressive disease that leads to overwhelming complications without an effective therapeutic approach. In recent decades, transplantation of mesenchymal stem cells (MSCs) has played promising role in the treatment FHN initial stage; however, success rate still low because unsuitable cell carriers and abridged osteogenic differentiation transplanted MSCs. Biopolymeric-derived hydrogels have been extensively applied as drug vesicles; they provide...

Osteoporosis and diabetes have become serious health problems worldwide. Previous studies suggested that is associated with osteoporosis increased fracture risk. However, the mechanism underlying diabetes‑induced remains to be elucidated. Therefore, present study aimed examine osteoporosis, determine protective effects of zinc, which known closely diabetes. The results demonstrated zinc inhibited advanced glycation end product (AGE)‑induced MC3T3‑E1 cell apoptosis by attenuating production...

In this study, the effects of Cu nanoparticles on melting characteristics, wettability, interfacial reaction and mechanical properties [Formula: see text]–[Formula: text] text], composite solders were investigated. Results show that solder containing improved effectively. With addition nanoparticles, point decreased significantly, spreading area shear strength increased by 10.3% 23.2%, respectively. For performance, optimal was 0.7%. addition, growth intermetallic compounds in joints...

Background: Osteosarcoma (OS) is a highly prevalent bone malignancy with poor clinical outcomes. Expression of the circular RNA, hsa_circ_0078767 (circFAM120B) elevated in OS, however, its mechanisms OS are unclear. Methods: CircFAM120B levels were detected tissue and cell lines. Silenced circFAM120B experiments performed to assess effects on vitro cancer phenotypes vivo tumor growth. Then, bioinformatics analyses used predict target microRNAs (miRNAs) associated genes. Results:...

The microstructure and properties of Sn lead-free solders with various carbon nanotubes (CNTs) contents (0, 0.025, 0.05, 0.075, 0.1, 0.125, wt. %) were studied. results indicate that the wettability mechanical solder joints both effectively improved when content CNTs was 0.075 %. Furthermore, adding % can refine structure inhibit formation brittle intermetallic compounds (IMCs). fracture mode specimen mainly ductile addition

Studies have revealed that consistency of liquid food changes with temperature. Yet, the exact relationship between temperature and bolus is still not known. The present study examined change in Water thickened at four thickness levels (slightly thick, mildly moderately extremely thick) using starch-based xanthan-gum-based thickeners was studied. Consistency measured a Bostwick consistometer different points 5 °C 85 °C. Regression analyses were subsequently carried out. Results indicated...