A5031484852- HIV, Drug Use, Sexual Risk
- Opioid Use Disorder Treatment
- HIV/AIDS Research and Interventions
- Substance Abuse Treatment and Outcomes
- Hepatitis C virus research
- Prenatal Substance Exposure Effects
- HIV-related health complications and treatments
- Homelessness and Social Issues
- Adolescent Sexual and Reproductive Health
- Health Policy Implementation Science
- Cannabis and Cannabinoid Research
- Hepatitis B Virus Studies
- Forensic Toxicology and Drug Analysis
- Liver Disease Diagnosis and Treatment
- HIV Research and Treatment
- COVID-19 epidemiological studies
- Suicide and Self-Harm Studies
- Criminal Justice and Corrections Analysis
- Digital Mental Health Interventions
- Cardiac Arrest and Resuscitation
- Meta-analysis and systematic reviews
- COVID-19 Clinical Research Studies
- Health Systems, Economic Evaluations, Quality of Life
- Primary Care and Health Outcomes
- Medication Adherence and Compliance
Cornell University
2017-2025
Weill Cornell Medicine
2021-2024
Northern National College
2022
New York University
2020
National Institute on Drug Abuse
2020
E Ink (South Korea)
2020
Gilead Sciences (United States)
2020
Northwestern University
2020
Wellcome / EPSRC Centre for Interventional and Surgical Sciences
2018
Josef Meissner (Germany)
2018
Many US states are substantially increasing community-based naloxone distribution, supported in part through settlements from opioid manufacturers and distributors. To evaluate the potential impact of increased availability on overdose deaths (OODs) explore strategies to enhance this by integrating interventions address solitary drug use. This decision analytical modeling study used PROFOUND (Prevention Rescue Fentanyl Other Opioid Overdoses Using Optimized Naloxone Distribution Strategies),...
Abstract Background Widespread viral and serological testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may present a unique opportunity to also test human immunodeficiency virus (HIV) infection. We estimated the potential impact of adding linked, opt-out HIV alongside SARS-CoV-2 on incidence cost-effectiveness this strategy in 6 US cities. Methods Using previously calibrated dynamic transmission model, we constructed 3 sets scenarios each city: (1) sustained current...
Objective: Effective interventions to reduce the public health burden of HIV/AIDS can vary in their ability deliver value at different levels scale and epidemiological contexts. Our objective was determine cost-effectiveness HIV treatment prevention implemented previously documented scales delivery six US cities with diverse microepidemics. Design: Dynamic transmission model-based analysis. Methods: We identified estimated costs for 16 evidence-based from CDC's Compendium Evidence-Based...
Abstract We estimated human immunodeficiency virus incidence and rate ratios (IRRs) for black Hispanic vs white populations in 6 cities the United States (2020–2030). Large reductions are possible, but without elimination of disparities healthcare access, we found that wide persisted compared with particular (lowest IRR, 1.69 [95% credible interval, 1.19–2.30]).
US overdose deaths have reached a record high. Syringe services programs (SSPs) play critical role in addressing this crisis by providing multiple to people who use drugs (PWUD) that help prevent death. This study examined the perspectives of leadership and staff from geographically diverse sample SSPs on factors contributing surge, their organization's response, ongoing barriers preventing
Syringe services programs (SSPs) provide critical evidence-based public health that decrease harms from drug use for people who drugs (PWUD). Many SSPs have experienced significant and evolving COVID-19-related disruptions. We aimed to characterize the impacts of COVID-19 on SSP operations in United States approximately two years into pandemic. Participating sites, selected a national sample SSPs, completed semi-structured interview via teleconference brief electronic survey evaluating...
Background. Heterogeneity in HIV microepidemics across US cities necessitates locally oriented, combination implementation strategies to prioritize resources. We calibrated and validated a dynamic, compartmental transmission model establish status quo treatment scenario, holding constant current levels of care for 6 cities. Methods. Built off comprehensive evidence synthesis, we adapted extended previously published replicate the transmission, progression, clinical each microepidemic....
In 2021, the state of Rhode Island distributed 10 000 additional naloxone kits compared with prior year through partnerships community-based organizations. To compare various strategies to increase distribution programs in identify one most effective and efficient strategy preventing opioid overdose deaths (OODs). this decision analytical model study conducted from January 2016 December 2022, a spatial microsimulation an integrated tree was developed calibrated outcomes alternative for...
Syringe service programs (SSPs) deliver critical harm reduction services to people who inject drugs (PWID). Some SSPs in New York State received enhanced funding provide additional combat opioid overdose fatalities. These SSPs, known as Drug User Health Hubs, buprenorphine for the treatment of use disorder and other health-related addition their syringe services. While COVID-19 pandemic posed widespread challenges delivery health nationwide, effect on uniquely impacts PWID. This study...
Early diagnosis of human immunodeficiency virus (HIV) infection and initiation antiretroviral treatment (ART) improves health outcomes prevents HIV transmission. Before 2010, testing was available to inmates in the California state prison system upon request. In Correctional Health Care Services (CCHCS) integrated opt-out screening into assessment for entering prisons. Under this system, a medical care provider informs inmate that an test is routinely done, along with sexually transmitted,...
Abstract We estimated 10-year (2020–2030) trajectories for human immunodeficiency virus incidence in 6 US cities. Estimated will only decrease 2 of cities, with the overall population-weighted decreasing 3.1% (95% credible interval [CrI], ˗1.0% to 8.5%) by 2025, and 4.3% CrI, ˗2.6% 12.7%) 2030 across Targeted, context-specific combination implementation strategies be necessary meet newly established national targets.
Abstract Background Persons involved in the justice system are at high risk for HIV and drug overdose upon release to community. This manuscript describes a randomized controlled trial of two evidence-based linkage interventions provision prevention treatment substance use disorder (SUD) services four communities assess which is more effective addressing these needs reentry community from system. Methods 5-year hybrid type 1 effectiveness-implementation that compares models (Patient...