About
Contact & Profiles
A5061621445
Research Areas
- Bioinformatics and Genomic Networks
- Computational Drug Discovery Methods
- Microbial Natural Products and Biosynthesis
Union Catholic Regional High School
2016
Target-based screening is one of the major approaches in drug discovery. Besides intended target, unexpected off-target interactions often occur, and many them have not been recognized characterized. The can be responsible for either therapeutic or side effects. Thus, identifying genome-wide off-targets lead compounds existing drugs will critical designing effective safe drugs, providing new opportunities repurposing. Although computational methods developed to predict drug-target...
10.1371/journal.pcbi.1005135
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PLoS Computational Biology
2016-10-07
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