A5110364388- Cancer-related molecular mechanisms research
- Prostate Cancer Treatment and Research
- Phytochemistry and Bioactive Compounds
- Bioactive Compounds and Antitumor Agents
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Fibroblast Growth Factor Research
- Lipid metabolism and disorders
- Advanced Glycation End Products research
- Corneal Surgery and Treatments
- Metabolism and Genetic Disorders
- Metabolomics and Mass Spectrometry Studies
- Mesenchymal stem cell research
- Alcohol Consumption and Health Effects
- Circular RNAs in diseases
- Mitochondrial Function and Pathology
- Phytochemical compounds biological activities
- Genetic Associations and Epidemiology
- Kruppel-like factors research
- Acute Kidney Injury Research
Changzhi Medical College
2017-2021
Ningxia Medical University
2020
Changzhi Medical College Peace Hospital
2019
Ophiopogonin D (OP-D) is the principal pharmacologically active ingredient from Ophiopogon japonicas, which has been demonstrated to have numerous pharmacological activities. However, its protective effect against renal damage in streptozotocin (STZ)-induced diabetic nephropathy (DN) rats remains unclear. The present study was performed investigate of OP-D STZ-induced DN rat model. showed dysfunction, as evidenced by decreased serum albumin and creatinine clearance, along with increases...
Long non-coding RNA psoriasis-susceptibilityrelated gene induced by stress (PRINS) is known to be involved in kidney ischemia reperfusion injury. The aim of the current study was investigate potential role PRINS diabetic nephropathy. relative mRNA expression level and SMAD family member 7 (Smad7) examined patients with diabetes, including without obvious complications (n=43), nephropathy (n=33), retinopathy (n=37), cardiomyopathy (n=29), lung disease (n=38) healthy controls (n=48)....
Limonin is one of the major active ingredients citrus. In present study, anti-angiogenic and anti-metastatic effects limonin were investigated.The Molecular docking assay was carried out to assess binding ability with VEGFR2 receptor. MTS used detect effect on proliferation breast cancer cells (MDA-MB-231, MCF-7). The Wound-healing Transwell chamber invasion assays inhibition migration HUVECs or cells. capillary-like tube formation Matrixgel plug experiment further measure in vivo activity...
Purpose: To investigate the preventive effect of resveratrol against renal pathological changes in a rat model chronic kidney disease (CKD).Methods: CKD was induced by daily intragastric administration adenine (200 mg/kg) for 1 month. The 10, 15, and 20 mg/kg doses on levels parathyroid hormone, phosphorous, fibroblast growth factor-23 (FGF-23) urine samples after 2 months were analyzed using an auto-analyzer.Results: Resveratrol treatment significantly inhibited adenine-mediated increase...
MiR-429 was reported to be downregulated in contrast-induced acute kidney injury (CI-AKI). However, whether miR-429 is functionally relevant with CI-AKI needs further investigation. Human renal tubular epithelial cell (HK-2) cells were stimulated contrast media iodixanol establish vitro model. Cell Counting Kit-8 (CCK-8) applied access viability. Flow cytometry performed determine apoptosis. Quantitative real-time polymerase chain reaction (qRT-PCR) evaluate level of programmed death 4...