A5084438200- Neurological Disorders and Treatments
- Diabetes Management and Research
- Diabetes Treatment and Management
- Diet, Metabolism, and Disease
- Diabetes and associated disorders
- GDF15 and Related Biomarkers
- Healthcare Systems and Public Health
- Nutrition, Genetics, and Disease
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Neuroblastoma Research and Treatments
- Neuroendocrine Tumor Research Advances
- Pancreatic function and diabetes
- Heart Rate Variability and Autonomic Control
- Cardiovascular Health and Risk Factors
- Vascular Tumors and Angiosarcomas
- Parathyroid Disorders and Treatments
- Macrophage Migration Inhibitory Factor
Krasnoyarsk Regional Clinical Hospital
2009-2025
Novosibirsk State Medical University
2021-2023
BACKGROUND : Type 2 diabetes mellitus (T2DM) is a disease with high prevalence and early mortality, identifying groups at risk for adverse outcomes important in secondary prevention. AIM To study clinical, metabolic genetic factors deaths various clinical phenotypes patients type the Novosibirsk region. MATERIALS AND METHODS: A prospective cohort was conducted of 2507 T2DM. The follow-up duration 6.3±2.5 years. Depending on level C-peptide HOMA-IR index, were divided into 3 phenotypes:...
BACKGROUND: There are no large-scale epidemiological studies on primary hyperparathyroidism (PHPT) in Russia. The high prevalence of the disease, risk disability and death this cohort patients requires study clinical structure PHPT to determine extent medical care. AIM: Evaluate frequency detection characterize its forms Russia using an online registry. METHODS: object is database State Register Patients with 1914 from 71 regions Russian Federation. New cases as well dynamic indicators...
Recently, a large number of studies have been conducted to investigate the variability response in treatment diabetes mellitus (T2DM), which make personalized medicine possible. However, available data are insufficient decide on choice sugar-lowering drugs T2DM. The search for phenotypic and clinical factors pharmacogenetic therapy continues. Aim study was relationship between effectiveness sulfonylurea structural variants ABCC8 (rs757110) KCNJ11 (rs5219) genes T2DM patients with phenotypes....
BACKGROUND: Diabetes mellitus (T2DM) is a serious medical and social problem. Now they are studying the possibility of new stratification diabetes. The cluster analysis for different durations diabetes, in cohorts to identify phenotypic clusters T2DM validation by reproducing relevant. AIM: Identify type 2 diabetes patients with disease duration based on five variables: HbA1c, age at diagnosis, BMI, HOMA-IR, HOMA-B study clinical features complication rates each Novosibirsk region. MATERIALS...
The results of the international multicenter study EMPEROR-Reduced have been discussed on October 31, 2020, at online expert meeting. Considering positive cardiovascular and renal effects empagliflozin, experts supported use empagliflozin in clinical practice to treat patients with chronic heart failure.
Hypoglycemic syndrome occurs not only in endocrine diseases but can complicate the course of many somatic and tumors pancreatic extra-pancreatic localization. Development hypoglycemia liver is associated with a decrease volume functioning tissue, increased consumption, utilization glucose by tumor inhibition gluconeogenesis glycogenolysis, secretion insulin-like peptides. Hypoglycemia rarely first symptom disease usually patients large sizes symptoms intoxication. Epithelioid...
Introduction . In recent years, there has been an increase in the prevalence and incidence diabetes type 1. The high-quality glycemic control is critical reducing risk of developing progression vascular complications adverse outcomes diabetes. Self-monitoring blood glucose (SMBG) professional continuous monitoring (PCGM) provide data set which must be interpreted using multiple indicators control. A number researchers have demonstrated relationship between time range (TIR) both micro-...
Rationale. The genetic aspects influencing the effectiveness of metformin (MF) therapy in patients with type 2 diabetes mellitus (DMT2) have recently been intensively studied. Objective — to study association between rs11212617 polymorphism ATM gene and response DMT2 Novosibirsk region conduct a metaanalysis previously reported data. Material methods. 460 (97 males 363 females) who received MF, both as part monotherapy combination sulfonylurea (SU) drugs, were subjected cross-sectional...
BACKGROUND : Type 2 diabetes mellitus (T2DM) is a heterogeneous disease. Determination of different T2DM phenotypes will improve the prediction metabolic disorders, risk complications and individual therapy. AIM: To identify clusters in patients with duration study frequency diabetic drug therapy Novosibirsk region. MATERIALS AND METHODS The was carried out at Diamodul period 2013–2017 K-means cluster analysis performed 2805 aged 44 to 75 years 7.84±6.53 based on 5 variables — HbA 1c , age...
The effects of Dibicor (taurine) were studied in 20 patients with type 2 diabetes (T2D) a disease duration 1 to 9 years and mean body weight 93.8±16 kg who received concomitant therapy (monotherapy sulfonylurea (n = 7), novonorm 1), metformin 7); one patient was on diet therapy). Addition the following 3 months caused statistically significant reduction fasting postprandial glycemia (from 7.9 6.3 mmol/l from 6.9 mmol/l, respectively). Glycated hemoglobin decreased 7.8 7.05% (p 0.062). Lipid...