A5067376073- Circular RNAs in diseases
- Advanced Nanomaterials in Catalysis
- RNA modifications and cancer
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Graphene and Nanomaterials Applications
- Cancer Mechanisms and Therapy
- Metabolism, Diabetes, and Cancer
- Liver physiology and pathology
- Carbon and Quantum Dots Applications
- Cancer, Lipids, and Metabolism
- Pancreatic function and diabetes
- Mercury impact and mitigation studies
- Oral microbiology and periodontitis research
- Advanced Drug Delivery Systems
- Bone Tissue Engineering Materials
- MicroRNA in disease regulation
- Nanoplatforms for cancer theranostics
- Autophagy in Disease and Therapy
- Cancer-related molecular mechanisms research
Guangxi Medical University
2024-2025
Eighth Affiliated Hospital of Sun Yat-sen University
2021-2024
Sun Yat-sen University
2021-2024
First Affiliated Hospital of Guangzhou Medical University
2015
Guangzhou Medical University
2015
Introduction Diabetes mellitus often leads to bone metabolism disorders, hindering regeneration and delaying the healing of defects. β-Ecdysone, a plant-derived hormone known for its wide range physiological activities, possesses hypoglycemic effects promotes osteogenic differentiation. This study developed composite PLGA slow-release scaffold loaded with β-ecdysone enhance bioavailability through topical administration investigate potential heal diabetic Methods The scaffolds were...
Background: Periodontitis, one of the most common oral diseases caused by bacterial infection which affects gums, periodontal ligament and alveolar bone, is a leading cause tooth loss in adults. Current clinical treatments, such as scaling or antibiotics, often result incomplete biofilm removal can contribute to drug resistance. Methods: To address these limitations, nanozyme comprising platinum, copper, selenium was developed, then incorporated into thermoresponsive hydrogel. Results: When...
Emerging evidence has demonstrated that circular RNAs (circRNAs) take part in the initiation and development of pancreatic ductal adenocarcinoma (PDA), a deadly neoplasm with an extremely low 5-year survival rate. Reprogrammed glucose metabolism is key feature tumour development, including PDA. In this research, we evaluated role circRNAs reprogrammed RNA sequencing under various incubation circumstances was performed. A new circMYOF identified. Sanger RNase R treatment confirmed its...
Abstract Background Somatic mutations of the TP53 gene occur frequently in pancreatic ductal adenocarcinoma (PDA). Solute carrier family 45 member A4 (SLC45A4) is a H + ‐dependent sugar cotransporter. The role SLC45A4 PDA, especially mutant remains poorly understood. Methods We explored TCGA datasets to identify oncogenes PDA. MTS [3‐(4,5‐dimethylthiazol‐2‐yl)‐5‐(3‐carboxymethoxyphenyl)‐2‐(4‐sulfophenyl)‐2H‐tetrazolium], colony formation and 5‐ethynyl‐2′‐deoxyuridine (Edu) assays were...
Abstract Emerging evidences has revealed that circular RNAs (circRNAs) participate in the initiation and development of pancreatic ductal adenocarcinoma (PDAC), a deadly malignancy with extremely low 5-year survival rate. Reprogrammed glucose metabolism is key feature tumor development, including PDAC. In this study, we aimed to investigate role circRNAs reprogrammed RNA sequencing under various incubation circumstance was performed. A new circMYOF identified. Sanger RNase R treatment...