A5065760891- Neural and Behavioral Psychology Studies
- Decision-Making and Behavioral Economics
- Neural dynamics and brain function
- Economic and Environmental Valuation
- Epigenetics and DNA Methylation
- RNA regulation and disease
- Ethics and Legal Issues in Pediatric Healthcare
- Wastewater Treatment and Nitrogen Removal
- Microbial Fuel Cells and Bioremediation
- Neonatal Respiratory Health Research
- MicroRNA in disease regulation
- EEG and Brain-Computer Interfaces
- Cancer-related molecular mechanisms research
- Autophagy in Disease and Therapy
- Pancreatic function and diabetes
- Neuroscience and Neural Engineering
- Lymphoma Diagnosis and Treatment
- Nerve injury and regeneration
- Functional Brain Connectivity Studies
- Autism Spectrum Disorder Research
- Chronic Lymphocytic Leukemia Research
- Monoclonal and Polyclonal Antibodies Research
- Genetics and Neurodevelopmental Disorders
- Capital Investment and Risk Analysis
- Microbial bioremediation and biosurfactants
Johns Hopkins University
2013-2023
Allen Institute for Brain Science
2020-2023
The First People's Hospital of Wenling
2017-2018
Wenzhou Medical University
2018
Children's Hospital of Zhejiang University
2017
National Medical Products Administration
2017
Zhejiang University
2007-2017
Zhejiang Cancer Hospital
2016
Johns Hopkins Medicine
2013
Abstract In humans, risk attitude is highly context-dependent, varying with wealth levels or for different potential outcomes, such as gains losses. These behavioral effects have been modelled using prospect theory, the key assumption that humans represent value of each available option asymmetrically a gain loss relative to reference point. It remains unknown how these computations are implemented at neuronal level. Here we show macaques, like change their across and gain/loss contexts...
Understanding how the brain reflects and shapes mood requires resolving disconnect between behavioral measures of that can only be made in humans (typically based on subjective reports happiness) detailed activity available animals. To achieve this, we developed a universal model to predict fluctuations human happiness as individuals experienced wins losses during gambling task. Next, investigated this operationalization was reflected brains two monkeys engaged same We found remarkable...
Journal Article Formation and microbial community analysis of chloroanilines‐degrading aerobic granules in the sequencing airlift bioreactor Get access L. Zhu, Zhu Department Environmental Engineering, Zhejiang University, Hangzhou, China Search for other works by this author on: Oxford Academic Google Scholar X. Xu, Xu 268 Kaixuan Road, Hangzhou 310029, China. E‐mail: xuxy@zju.edu.cn W. Luo, Luo D. Cao, Cao Y. Yang Applied Microbiology, Volume 104, Issue 1, 1 January 2008, Pages 152–160,...
Background: Numerous reports have shown that a combination of two or more drugs leads to better cancer treatment. Inhibitors zeste homology 2 and epidermal growth factor receptor been widely used in treatments. However, the mechanisms combined use these remain elusive. Methods: Sulforhodamine B assays Alexa Fluor ® -488 Annexin V/Dead Cell Apoptosis Kit were detect cell proliferation apoptosis vitro, respectively. Western blotting analysis was relative protein expression, xenografted tumor...
Abstract Autism spectrum disorder (ASD) is a complex neurodevelopmental that has strong genetic component. Disruptions of FOXP1, transcription factor expressed in the developing cerebral cortex, were associated with ASD. FOXP1(R525X) de novo heterozygous mutation found patients autism and severe mental retardation. To explore neuronal basis ASD, we created Foxp1(R521X), mouse homolog human variant. Ectopic expression Foxp1(R521X) led to cytoplasmic aggregates activated macroautophagy...
Abstract Real-life decisions typically involve multiple options, each with attributes affecting value. In such complex cases, sequential shifts of attention to specific options and are thought guide the decision process. We designed a task that allowed us monitor in monkeys engaged multi-attribute decisions. recorded pre-supplementary motor area neurons encoding action value signals reflecting Attention guides this process through two mechanisms. First, enhances activity representing...
<title>Abstract</title> Models of multi-attribute decision making vary on whether all or only part the information available is being processed, as well preference formation based within-option within-attribute processing. Here we carry out a combined empirical and computational study in which rely lottery-options with varying task complexities. We monitor eye-gaze during to determine decision-relevant participants attend, when. then compare large set models, different levels complexity...
Abstract In humans, risk attitude is highly context-dependent, varying with wealth levels or for different potential outcomes, such as gains losses. These behavioral effects are well described by Prospect Theory, the key assumption that humans represent value of each available option asymmetrically gain loss relative to a reference point. However, it remains unknown how these computations implemented at neuronal level. Using new token gambling task, we found macaques, like change their...
Abstract Traditional models of decision making under uncertainty explain human behavior in simple situations with a minimal set alternatives and attributes. Some them, such as prospect theory, have been proven successful robust situations. Yet, less is known about the preference formation during more complex cases. Furthermore, it generally accepted that attention plays role process but most theories make simplifying assumptions where deployed. In this study, we replace these by measuring...