A5011766444- Diet and metabolism studies
- Cardiovascular Health and Disease Prevention
- Human Health and Disease
- Genetic Associations and Epidemiology
- Nutritional Studies and Diet
- Birth, Development, and Health
- Gut microbiota and health
- Tryptophan and brain disorders
- GDF15 and Related Biomarkers
- Forensic and Genetic Research
- Public Health and Nutrition
- Cultural Differences and Values
- Cardiovascular Disease and Adiposity
- Cardiac, Anesthesia and Surgical Outcomes
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Genomics and Rare Diseases
- Biomarkers in Disease Mechanisms
- Diabetes Management and Research
- Health, psychology, and well-being
Federal Almazov North-West Medical Research Centre
2023-2024
First Pavlov State Medical University of St. Petersburg
2023
Abstract The population of Russia consists more than 150 local ethnicities. ethnic diversity and geographic origins, which extend from eastern Europe to Asia, make the uniquely positioned investigate shared properties inherited disease risks between European Asian ancestries. We present analysis genetic phenotypic data a cohort 4,145 individuals collected in three metro areas western Russia. show presence multiple admixed ancestry clusters spanning primarily high identity-by-descent sharing...
Abstract The population of Russia consists more than 150 local ethnicities. ethnic diversity and geographic origins, which extend from eastern Europe to Asia, make the uniquely positioned investigate shared properties inherited disease risks between European Asian We present analysis genetic phenotypic data a cohort 4,145 individuals collected in three metro areas western Russia. show presence multiple admixed ancestry clusters spanning primarily high identity-by-descent sharing with Finnish...
The impact of adverse factors in the early life can affect rate vascular aging adulthood and be passed on to next generations. Aim. To study characteristics arterial stiffness phenotypes two generations descendants (children grandchildren) siege Leningrad survivors, compared a control group. Material methods. Residents who experienced famine during childhood Great Patriotic War (19411944) underwent examination between 2009 2014. In 2020-2021, 76 aged 18 63 years — 54 (first generation)...
Surrogate markers quantifying the severity of intestinal inflammation (fecal calprotectin) and permeability zonulin) are currently considered nontraditional cardiovascular risk factors. Aim. To study associations fecal zonulin calprotectin levels with factors target organ damage among participants metabolic disorders from a population sample St. Petersburg residents aged 35-75 years. Material methods. In-depth phenotyping was performed on patients cohort (overweight, hyperglycemia) invited...
Objective: We aimed to compare the new body indices against traditional mass index in their ability predict diabetes development patients with fasting hyperglycemia. Design and method: Baseline examination of population-based cohort was performed 2012-2013 framework epidemiological study ESSE-RF which included questionnaires, anthropometry (weight, height, waist hip circumference), laboratory tests (fasting glucose, glycated hemoglobin, lipids) target organ damage assessment. In 2022-2023...
Objective: To identify associations of fecal zonulin with cardiovascular risk factors including vascular damage in population-based sample. Design and method: 77 patients without disease from a sample were randomly invited signed informed consent. All underwent questionnaire (eating habits, physical activity, smoking, alcohol consumption, stress, anxiety, depression, quality life, EFPQ), anthropometry, blood pressure pulse measurement, laboratory examination (biochemical test, lipids,...
Objective: To identify associations of fecal calprotectin with cardiovascular risk factors including vascular damage in population-based sample. Design and method: 77 patients without diseases from sample were randomly invited signed informed consent. All underwent a questionnaire (eating habits, physical activity, smoking, alcohol consumption, stress, anxiety depression, quality life, EFPQ), anthropometry, blood pressure pulse measurement, laboratory examination (biochemical test, lipids,...
In recent years, an increasing number of studies have shown a close relationship between the composition and function microbiota human health, including cardiovascular diseases (CVD). Increased intestinal permeability is one factors that can influence state also lead to penetration bacteria their toxins into bloodstream, causing systemic inflammation. Chronic inflammation, in turn, accompanied by increased levels cytokines, which cause endothelial damage dysfunction. Metabolites some reduce...