Р. А. Либис
A5088918067- Healthcare Systems and Public Health
- Blood Pressure and Hypertension Studies
- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Human Health and Disease
- Cardiac Health and Mental Health
- Cardiovascular Disease and Adiposity
- Heart Failure Treatment and Management
- Lipoproteins and Cardiovascular Health
- Cardiovascular Health and Disease Prevention
- Diet and metabolism studies
- Obesity, Physical Activity, Diet
- Hormonal Regulation and Hypertension
- Sodium Intake and Health
- Atrial Fibrillation Management and Outcomes
- Heart Rate Variability and Autonomic Control
- Diabetes Treatment and Management
- Cardiovascular Health and Risk Factors
- Nutritional Studies and Diet
- Cardiac, Anesthesia and Surgical Outcomes
- Neurological Disorders and Treatments
- Diet, Metabolism, and Disease
- Genetic Associations and Epidemiology
- Cerebrovascular and Carotid Artery Diseases
- Heart rate and cardiovascular health
Orenburg State Medical Academy
2015-2024
Samara State Medical University
2022
Orenburg State Pedagogical University
2021
Russian Society of Cardiology
2020
University of Leeds
2019
Leeds Teaching Hospitals NHS Trust
2019
Sir Ganga Ram Hospital
2018
KLE Society Hospital
2018
Duke Medical Center
2016
Arterial hypertension in adults. Clinical guidelines 2020
In the frame of Multicenter observational study ECVD-RF (Epidemiology Cardiovascular Diseases and their Risk Factors in Regions Russian Federation) by unique protocol investigation representative selections adult population at age 25-64 y.o. 11 regions RF (n=18305, including males, n=6919 females n=11386): Volgograd, Vologda, Voronezh, Ivanovo, Kemerovo, Orenburg, Samara, Tomsk, Tyumen, Saint-Petersburg Northern Osetia-Alania. The prevalence following risk factors (RF) cardiovascular...
Aim. To study prevalence of arterial hypertension (AH), mean values systolic and diastolic blood pressure (SBP, DBP), awareness patients about their disease, medication consumption (MC) efficacy treatment in several regions Russia. Material methods. Representative selections were made 9 Russia: men (n=5563), women (n=9737) 25–64 y.o., studied 2012–2013 with the response 80%. Systematic stratified multilevel random selection was formed localilty criteria (Kisch method). The Questionnaire on...
The Russian Society of Cardiology (RKO) With the participation of: Scientific Medical Internal Medicine (RSMSIM) Approved by Research and Practical Council Ministry Health Federation (12.09.2024)
Russian Society of Cardiology (RSC) With the participation: National Myocardial Diseases and Heart Failure, Failure Specialists, Scientific Medical Internal Medicine Endorsed by Research Practical Council Ministry Health Federation (12.09.2024)
To study the prevalence of anxiety and depression by psychometric methods (the Hospital Anxiety Depression Scale (HADS) in different regions Russian Federation (RF), which are characterized various climatic, geographic, economic, demographic indicators.The investigation used data multicenter epidemiological survey cardiovascular diseases Federation--the ESSE-RF study. The subjects were representative samples from unorganized male female populations aged 25-64 years 10 RF regions. included a...
High plasma triglyceride (TG) is an independent risk factor for cardiovascular disease. Fibrates lower TG levels through peroxisome proliferator-activated receptor α (PPARα) agonism. Currently available fibrates, however, have relatively low selectivity PPARα. The aim of this trial was to assess the safety, tolerability, and efficacy K-877 (pemafibrate), a selective PPARα modulator, in statin-treated European patients with hypertriglyceridemia.A total 408 adults were recruited from 68 sites...
Aim. To study the prevalence of hyperuricemia in Russian regions, depending on climatic, geographical, socio-demographic characteristics and some cardiometabolic risk factors. Material methods. Data from ESSE-RF 10 regions theRussian Federationare presented. All participants were examined according to a uniform protocol. Measurements standardized, biochemical tests carried out three Federal centers using same methodology. The was approved by independent Ethics committees, all signed informed...
Abstract The population of Russia consists more than 150 local ethnicities. ethnic diversity and geographic origins, which extend from eastern Europe to Asia, make the uniquely positioned investigate shared properties inherited disease risks between European Asian ancestries. We present analysis genetic phenotypic data a cohort 4,145 individuals collected in three metro areas western Russia. show presence multiple admixed ancestry clusters spanning primarily high identity-by-descent sharing...
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Physical activity (PA) is an important behavioral factor associated with the quality of life and healthy longevity. We hypothesize that extremely low high levels daily PA (including occupational PA) may have a negative impact on sleep psychological well-being.The aim study to investigate association between level type problems in adult population.The sample consisted participants from population-based cohort The Epidemiology Cardiovascular Risk Factors Diseases Regions Russian Federation...
Aim. To assess rate of familiarity and specifics treatment with statins among the citizens economically active age various cardiovascular risk by data from epidemiological study ESSE-RF (Epidemiology Cardiovascular Diseases in Different Russian Federation Regions). Material methods. In work was used, representative selection non-organized male female inhabitants aged 25-64 y.o. 13 regions, investigated during 2012-2014. Responded ~80%. The included questionning standard scale that on...
Aim . To study the contribution of hypertension (HTN) to survival and mortality in Russian population. Material methods This prospective observational cohort included representative samples from 11 regions (men women aged 25-64 years, n=18251) examined 2012-2014 as part Epidemiology Cardiovascular Diseases their Risk Factors Regions Federation (ESSE-RF) study. The examination a questionnaire (12 modules), anthropometric blood pressure (BP) measurements, well biochemical tests. HTN was...
In recent years, there has been a tendency for the population to change in different age categories. The age-related resonance is due, among other things, continuing high cardiovascular morbidity. Metabolic predictors play key role development of this pathology. aim study was identify specifics changes and combinations metabolic disorders risk developing events. Materials methods: 499 people aged 35 74 years participated study. follow-up period 36 months. All patients underwent an analysis...
Aim of the RUssian hoSpital Heart Failure Registry (RUS-HFR) was to analyze clinical and epidemiological characteristics, application modern drug non-drug therapy among hospitalized patients with systolic chronic heart failure (CHF) in 3 subjects Russian Federation.We conducted a prospective multicenter observational study cardiological centers (Petersburg, Orenburg, Samara) which we recruited aged 18-75 years left ventricular ejection fraction less or equal 40% without ongoing myocardial...
Aim. To study the prevalence of ischemic heart disease as one most common cardiovascular disorders, together with arterial hypertension (AH), diabetes mellitus (DM) and liver diseases (LD) in adult (25-64 y.o.) population selected RF regions, variance those gender age, association risk factors (FR). Material methods. Into analysis we included results representative selections studies from 13 studied according to program multicenter ESSE-RF during years 20122014; totally 21923 patients...
Aim. To study the prevalence of familial hypercholesterolemia (FH), characteristics clinical features and treatment disease in selected regions Russian Federation, this article describes design initial patients included study. Material methods. The participants were among those “Epidemiology cardiovascular risk factors diseases Federation” (ESSE-RF) different Federation. individuals with lowdensity lipoprotein cholesterol (LDL-C) levels >4.9 mmol/l or LDL-C >1.8 mmol/l, but ≤4.9 during...
Aim . To study the associations of subclinical and clinical anxiety depression, assesed by Hospital Anxiety Depression Scale (HADS), ≥8 points ≥11 points, respectively, with all-cause mortality cardiovascular mortality, as well total number nonfatal events (CVEs) in Russia. Material methods The included male female population aged 25-64 years from Epidemiology Cardiovascular Diseases their Risk Factors Regions Russian Federation (ESSE-RF) who signed an informed consent. 16941 people (men,...
Aim. To study social and economic gradients — educational occupational statuses, wealth level, behavioral risk factors (FR) in Russian population by the ESSE-RF data. Material methods. The data for analysis consisted of representative selections 13 regions RF (n=22906) participants study, incl. men (n=8353) women (n=13553) 25-64 y.o., with response 80%. We calculated odds ratios presence FR: smoking, excessive alcohol consumption, insufficient physical activity (IPA), nonrational food...
Abstract The population of Russia consists more than 150 local ethnicities. ethnic diversity and geographic origins, which extend from eastern Europe to Asia, make the uniquely positioned investigate shared properties inherited disease risks between European Asian We present analysis genetic phenotypic data a cohort 4,145 individuals collected in three metro areas western Russia. show presence multiple admixed ancestry clusters spanning primarily high identity-by-descent sharing with Finnish...
Aim. To evaluate 10-year risk of potential development type 2 diabetes (DM) in Russian population with the FINDRISC score, and to assess its associations social, demographic behavioral factors by data from epidemiological study ESSE-RF. Material methods. In work, used, multi-center (Epidemiology cardiovascular diseases various regions Federation: ESSE-RF). Totally, 21923 persons investigated, age 25-64 y.o., those 1045 (3,76% males, 5,39% females) had DM. final analysis 20878 included (8058...
Aim. To study the association of heart rate (HR) with health parameters obtained in ESSE-RF study. Material and methods . The data multicenter epidemiological were used work. 8,343 men 13,531 women aged 25-64 years examined. response to survey was about 80%. analysis is performed depending on elevated rate. Education, place residence, region, lipid profile, levels C-reactive protein (CRP) glucose, history diabetes, anxiety depression, blood pressure analyzed as factors possibly associated...
Aim . To perform a population analysis of Non-High Density Lipoprotein Cholesterol level (non-HDL-c) in Russian and to evaluate its association with cardiovascular events. Material Methods The material consisted results obtained from 11 regions the ESSE-RF1 Study 4 ESSE-RF2 Study. protocols were identical. studies performed 2012-2014 2017, respectively. Endpoints assessed 19041 people aged 35-64 years. median follow-up was 6.5 years ESSE RF (1) 3.8 RF(2). Analysis for three lipid variables:...