In Brief Objective: The present study evaluated the oncological safety and technical outcomes following nipple areola skin-sparing mastectomy (NASSM), (SSM), mastectomy. Summary Background Data: Cosmetic issues associated with breast cancer surgery are important. original SSM technique included removal of gland complex (NAC). However, risk tumor involvement NAC has been overestimated. Patients Methods: This retrospective 520 patients who underwent (368 patients) or NASSM (152 immediate...

Among hundreds of pathophysiologic factors that impair healing the diabetic foot, diminished perfusion and neovascularization are critical. This study aimed to show effect human adipose-derived stem cells on ischemic wounds in nude mice thus estimate possibilities for wound care.Sixty were assigned randomly into group Ia (diabetic control, n = 20), Ib experimental, or II (nondiabetic 20). After creation an limb, injected locally. Gross histologic observations made after 3, 7, 25 days, plasma...

Background: Immediate breast reconstruction using the transverse rectus abdominis musculocutaneous (TRAM) flap is associated with multiple risk factors for pulmonary thromboembolism, incidence of which has been reported to be as high 6.3 percent. The authors conducted a prospective study efficacy prophylactic use low-molecular-weight heparin prevent thromboembolism. Methods: Six hundred fifty consecutive patients who underwent immediate TRAM flaps between August 2001 and April 2007 were...

Abstract Background and Objectives Skin sparing mastectomy (SSM) has been demonstrated as an oncologically safe procedure for early breast cancer in several studies. But few studies concerned the safety of SSM patients with locally advanced cancer; therefore, its these is less clear. The purpose this study to examine oncological followed by immediate reconstruction cancer. Methods We retrospectively analyzed 897 who underwent stage IIB (T3N0)‐III between 1996 2005. Of 897, 87 (n = 73) or...

Background: A serious drawback of the deep inferior epigastric perforator (DIEP) flap is an abdominal scar that too high. Because umbilicus should be incorporated into territory, lowering very difficult. This report describes a new DIEP design where placed in lowermost part abdomen, well below umbilicus, similar to mini-abdominoplasty. Methods: The low was used only for cases with moderately sized breasts and reliable perforators way umbilicus. flap's lower border on pubic rim upper usually...

Abstract Extracellular matrix (ECM) remodeling dynamically occurs to accommodate adipose tissue expansion during obesity. One non-fibrillar component of ECM, biglycan, is released from the in response stress; soluble form biglycan binds toll-like receptor 2/4 on macrophages, causing proinflammatory cytokine secretion. To investigate pattern and regulatory properties expression human tissues context obesity its related diseases, we recruited 21 non-diabetic obese women, 11 type 2 diabetic 59...

In Brief Fat necrosis in transverse rectus abdominis musculocutaneous (TRAM) flap is considered to be mainly affected by blood supply. This prospective study compares the incidence of fat between zones II and III 400 consecutive patients who had undergone unipedicled TRAM breast reconstruction. Fifty-eight (14.5%) suffered from necrosis, 7 2 separate nodules. Fifty-four occurred zone II, 10 III, 1 I. The was significantly higher than (P < 0.001). weight mastectomy specimen relative amount...

Although free flap has largely replaced pedicled transverse rectus abdominis musculocutaneous (TRAM) flap, the latter also evolved by increased understanding of anatomy and physiology. We report outcomes in 500 consecutive TRAM Asian patients performed a single surgeon, providing incidences complications ideas prevention. Fascia was minimally harvested with full width muscle. The eighth intercostals nerve severed back-cut made at lateral belly. Anterior sheath directly repaired. Breast...

Nipple-sparing mastectomy (NSM) is gaining popularity due to its superior aesthetic results. When reconstructing the breast with free abdominal tissue transfer, we must readdress recipient vessel, because NSM can cause difficulty in access chest vessel.Between June 2006 and March 2011, a total of 92 women underwent transfer. A lateral oblique incision was used for nipple-sparing mastectomy. For vessels, internal mammary vessels were chosen if flap did not block vessels. If it did,...

Background No consensus has been reached regarding the outcome of management local recurrence after transverse rectus abdominis myocutaneous (TRAM) flap breast reconstruction. This study demonstrated presentation, management, and outcomes immediate TRAM Methods A comparison was conducted among 1,000 consecutive patients who underwent reconstruction with a pedicled (TRAM group) 3,183 only modified radical mastectomy without (MRM from January 2001 to December 2009. The treatment, including...

Background Numerous procedures are available for nipple reconstruction without a single gold standard. This study presents method reducing donor-site morbidity in using composite graft after transverse rectus abdominis musculocutaneous flap breast reconstruction. Methods Thirty-five patients who underwent technique between July of 2001 and December 2009 were enrolled this study. To reduce the donor site morbidity, superior or superior-medial half dome harvesting was applied preserving...

Arteriovenous malformations are high flow lesions that remain a challenge in the field of plastic surgery, interventional radiology, and neurosurgery. This is especially true for large requiring comprehensive team approach. From March 2001 to August 2004, six patients with arteriovenous malformation having extensive involvement skin underwent selective embolization followed by resection reconstruction anterolateral thigh perforator flap. The age ranged from 22 43 years (average, 29 years);...

Objective The traditional unilateral or bilateral buccogingival bicoronal approach often seems to impose limitations on achieving complete resection and reconstruction of the extensive midfacial fibrous dysplasia. Therefore, we hypothesized that degloving could be used for correction maxillary dysplasia, which has been primarily paranasal sinus lesions nasopharyngeal tumor. Methods study involved 5 maxillofacial dysplasia patients who underwent a surgical procedure. There were 4 male 1...

Topical anesthetics, such as eutectic mixture of local anesthetics (EMLA) cream, can be applied to reduce pain before minor procedure. This trial evaluated EMLA pretreatment for facial lacerations and compared pain, discomfort overall satisfaction.This included consecutive emergency department patients ≥16 years age who presented with simple lacerations. At triage, were allotted either the routine processing group or according date admission. Initially, doctors inspected each laceration,...

This study aimed to compare the oncologic outcomes of nipple-sparing mastectomy (NSM)/skin-sparing (SSM) followed by immediate reconstruction with those conventional (CM) in young patients aged under 35 years old breast cancer.We analyzed retrospectively 2889 who underwent for cancer at Asan Medical Center from January 2003 December 2008. We compared NSM/SSM CM analyzing clinicopathologic features, specific survival rate (BCSS), distant metastasis free (DMFS), and local recurrence (LRR).Out...

To clarify the clinical features of microform cleft lip and to establish ultrastructural characteristics orbicularis muscle.Clinical observations characteristic deformities associated anomalies were made. Muscle biopsies harvested for histologic analyses.Seventy-one consecutive patients with included in study. investigated 11 among them.Nasal deformity, a ridge or groove from vermilion nostril sill, interruption "white roll" present all patients. Lack philtral column free border notch was...

To evaluate the oncological outcomes of patients with breast cancer after nipple-sparing mastectomy (NSM)/skin-sparing (SSM), followed by immediate reconstruction, as compared to conventional (CM). SSM/NSM has been increasingly used treat women who wish preserve overlying skin, but concern exist regarding its safety due potential for residual tissue. We report our experience performing treatment CM a long follow-up period. All consecutive underwent at Asan Medical Center between January 1993...

Background Microvascular complications after free-flap breast reconstructions are potentially devastating problems that can increase patient morbidity and lead to flap loss. To date, no comprehensive study has examined the rates of salvage methods microvascular revision in reconstruction. We reviewed treatment reconstruction procedures over a seven-year period. Methods A retrospective review all patients who underwent at our institution between April 2006 December 2013 was conducted. Based...

A number of investigators have reported on the clinically significant relationship between diabetes mellitus and impaired wound healing. Diabetic patients an increased frequency infection, delayed scar formation, poor bony union. Investigations completed in our laboratory demonstrated that insulin-like growth factor type 1 (IGF-1), a somatomedin C, has shown promise for accelerating repair. The purpose this study was to examine effects recombinant IGF-1 standardized, critical-size calvarial...

Bromidrosis is a condition of abnormal offensive body odor caused mostly by apocrine gland secretion from the axilla. Although no morbid sequelae are known, can be disturbing enough to cause social impairment and psychological distress. Medical care available but temporary yields limited clinical benefit. Surgical treatment may provide more definite remedy through reduction gland. However, there risks for complication following surgical such as subdermal excision, subcutaneous shaving, en...

Abdominal wall free flaps are used most frequently in autologous breast reconstruction, and these require intact robust deep inferior epigastric perforator (DIEP) vessels. Pfannenstiel incisions often present during preoperative visits for reconstruction could potentially signal compromised blood supply to the lower abdominal wall. In this study, we compared number of DIEP vessels between patients with without undergoing reconstruction.A retrospective review medical records was performed...